[Hub]/) : Traits : Cardiovascular Disease :

chr7:6,502,367-7,988,091

Best TWAS P=3.84e-16 · Best GWAS P=8.92e-16 conditioned to 0.0299

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C1GALT1 0.26 0.15 enet 20 0.23 1.1e-27 5.159 7.5 4.9e-14 0.68 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous C1GALT1 0.20 0.14 enet 18 0.15 1.5e-12 5.167 5.5 4.2e-08 0.48 1.00 0.00 FALSE
3 GTEx Brain Caudate basal ganglia C1GALT1 0.27 0.18 enet 8 0.20 2.4e-06 8.041 7.8 6.0e-15 0.93 0.00 0.99 FALSE
4 GTEx Brain Cerebellar Hemisphere C1GALT1 0.33 0.24 lasso 4 0.20 6.1e-06 6.484 6.2 5.1e-10 0.66 0.12 0.77 FALSE
5 GTEx Brain Cortex C1GALT1 0.32 0.10 lasso 13 0.13 1.9e-04 8.041 7.2 5.5e-13 0.90 0.01 0.97 FALSE
6 GTEx Brain Frontal Cortex BA9 C1GALT1 0.38 0.28 enet 21 0.16 5.2e-05 5.167 5.7 1.3e-08 0.54 0.28 0.54 FALSE
7 GTEx Brain Nucleus accumbens basal ganglia C1GALT1 0.28 0.00 enet 28 0.01 1.8e-01 8.041 7.8 8.8e-15 0.86 0.01 0.93 FALSE
8 GTEx Breast Mammary Tissue C1GALT1 0.23 0.15 lasso 8 0.15 5.1e-08 7.805 7.6 2.4e-14 0.97 0.00 1.00 FALSE
9 GTEx Breast Mammary Tissue (Male) C1GALT1 0.00 0.03 lasso 1 0.09 4.0e-03 7.805 7.8 6.0e-15 0.99 0.03 0.44 FALSE
10 GTEx Cells Transformed fibroblasts C1GALT1 0.12 0.03 lasso 3 0.05 1.0e-04 5.167 6.7 2.2e-11 0.73 0.01 0.97 FALSE
11 GTEx Colon Sigmoid C1GALT1 0.52 0.25 enet 38 0.31 1.0e-11 8.041 7.5 5.4e-14 0.84 0.00 1.00 FALSE
12 GTEx Colon Transverse C1GALT1 0.32 0.23 lasso 4 0.30 8.0e-15 6.993 7.6 3.0e-14 0.78 0.34 0.66 FALSE
13 GTEx Esophagus Mucosa C1GALT1 0.33 0.19 lasso 6 0.18 2.8e-12 7.278 8.1 4.1e-16 0.85 0.06 0.94 TRUE
14 GTEx Esophagus Muscularis C1GALT1 0.36 0.16 lasso 8 0.27 1.9e-16 6.082 7.3 2.1e-13 0.74 0.57 0.43 FALSE
15 GTEx Heart Left Ventricle C1GALT1 0.17 0.04 enet 23 0.05 1.5e-03 7.278 7.3 2.1e-13 0.69 0.02 0.94 FALSE
16 GTEx Lung C1GALT1 0.18 0.13 lasso 3 0.15 1.1e-11 6.082 8.1 4.8e-16 0.80 0.01 0.99 FALSE
17 GTEx Nerve Tibial C1GALT1 0.44 0.28 lasso 12 0.40 2.0e-30 5.167 7.4 1.1e-13 0.76 0.97 0.03 FALSE
18 GTEx Ovary C1GALT1 0.22 0.14 enet 11 0.15 1.8e-04 6.476 7.0 3.7e-12 0.81 0.10 0.61 FALSE
19 GTEx Pancreas C1GALT1 0.44 0.11 enet 24 0.22 8.8e-10 5.167 7.2 7.4e-13 0.76 0.11 0.89 FALSE
20 GTEx Skin Sun Exposed Lower leg C1GALT1 0.22 0.04 lasso 9 0.10 4.8e-09 6.484 8.0 1.1e-15 0.78 0.02 0.98 FALSE
21 GTEx Spleen C1GALT1 0.56 0.29 lasso 6 0.46 3.2e-13 6.906 5.9 3.3e-09 0.70 0.04 0.95 FALSE
22 GTEx Stomach C1GALT1 0.24 0.07 enet 17 0.12 1.9e-06 6.906 6.9 4.5e-12 0.75 0.54 0.42 FALSE
23 GTEx Thyroid C1GALT1 0.30 0.27 lasso 3 0.31 3.9e-24 5.167 6.9 4.1e-12 0.68 1.00 0.00 FALSE
24 GTEx Uterus C1GALT1 0.38 0.28 enet 8 0.32 2.0e-07 6.993 7.3 2.4e-13 0.85 0.09 0.80 FALSE
25 METSIM Adipose C1GALT1 0.22 0.16 lasso 9 0.23 5.1e-34 8.041 8.1 5.7e-16 0.85 0.00 1.00 FALSE
26 ROSMAP Brain Pre-frontal Cortex C1GALT1 0.24 0.13 lasso 5 0.23 4.6e-29 -0.063 5.5 3.4e-08 0.63 0.69 0.31 FALSE
27 YFS Blood C1GALT1 0.35 0.20 enet 45 0.32 4.3e-109 6.082 6.1 1.3e-09 0.64 1.00 0.00 FALSE
28 The Cancer Genome Atlas Breast Invasive Carcinoma C1GALT1 0.02 0.01 lasso 4 0.01 1.7e-02 5.159 6.1 1.1e-09 0.52 0.06 0.69 FALSE
29 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1GALT1 0.22 0.11 enet 20 0.16 3.4e-18 6.993 5.9 4.5e-09 0.66 0.62 0.38 FALSE
30 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1GALT1 0.16 0.12 lasso 7 0.14 3.7e-08 7.926 8.0 1.2e-15 0.84 0.01 0.99 FALSE
31 The Cancer Genome Atlas Brain Lower Grade Glioma C1GALT1 0.13 0.06 blup 112 0.10 1.7e-11 8.041 5.3 1.2e-07 0.69 0.00 1.00 FALSE
32 The Cancer Genome Atlas Lung Adenocarcinoma C1GALT1 0.08 0.03 blup 112 0.06 2.5e-07 -0.750 5.3 1.4e-07 0.63 0.74 0.26 FALSE
33 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C1GALT1 0.27 0.06 enet 22 0.10 8.1e-05 6.903 7.1 9.4e-13 0.58 0.25 0.20 FALSE
34 The Cancer Genome Atlas Prostate Adenocarcinoma C1GALT1 0.12 0.05 enet 10 0.13 9.9e-14 5.159 6.1 1.2e-09 0.65 0.54 0.46 FALSE
35 The Cancer Genome Atlas Thyroid Carcinoma C1GALT1 0.05 0.01 lasso 2 0.01 3.8e-02 7.805 8.1 3.8e-16 0.96 0.00 0.95 FALSE