[Hub]/) : Traits : Cardiovascular Disease : ← →

chr7:6,502,367-7,988,091

Best TWAS P=3.84e-16 · Best GWAS P=8.92e-16 conditioned to 0.0299

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C1GALT1	0.26	0.15	enet	20	0.23	1.1e-27	5.159	7.5	4.9e-14	0.68	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	C1GALT1	0.20	0.14	enet	18	0.15	1.5e-12	5.167	5.5	4.2e-08	0.48	1.00	0.00	FALSE
3	GTEx	Brain Caudate basal ganglia	C1GALT1	0.27	0.18	enet	8	0.20	2.4e-06	8.041	7.8	6.0e-15	0.93	0.00	0.99	FALSE
4	GTEx	Brain Cerebellar Hemisphere	C1GALT1	0.33	0.24	lasso	4	0.20	6.1e-06	6.484	6.2	5.1e-10	0.66	0.12	0.77	FALSE
5	GTEx	Brain Cortex	C1GALT1	0.32	0.10	lasso	13	0.13	1.9e-04	8.041	7.2	5.5e-13	0.90	0.01	0.97	FALSE
6	GTEx	Brain Frontal Cortex BA9	C1GALT1	0.38	0.28	enet	21	0.16	5.2e-05	5.167	5.7	1.3e-08	0.54	0.28	0.54	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	C1GALT1	0.28	0.00	enet	28	0.01	1.8e-01	8.041	7.8	8.8e-15	0.86	0.01	0.93	FALSE
8	GTEx	Breast Mammary Tissue	C1GALT1	0.23	0.15	lasso	8	0.15	5.1e-08	7.805	7.6	2.4e-14	0.97	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue (Male)	C1GALT1	0.00	0.03	lasso	1	0.09	4.0e-03	7.805	7.8	6.0e-15	0.99	0.03	0.44	FALSE
10	GTEx	Cells Transformed fibroblasts	C1GALT1	0.12	0.03	lasso	3	0.05	1.0e-04	5.167	6.7	2.2e-11	0.73	0.01	0.97	FALSE
11	GTEx	Colon Sigmoid	C1GALT1	0.52	0.25	enet	38	0.31	1.0e-11	8.041	7.5	5.4e-14	0.84	0.00	1.00	FALSE
12	GTEx	Colon Transverse	C1GALT1	0.32	0.23	lasso	4	0.30	8.0e-15	6.993	7.6	3.0e-14	0.78	0.34	0.66	FALSE
13	GTEx	Esophagus Mucosa	C1GALT1	0.33	0.19	lasso	6	0.18	2.8e-12	7.278	8.1	4.1e-16	0.85	0.06	0.94	TRUE
14	GTEx	Esophagus Muscularis	C1GALT1	0.36	0.16	lasso	8	0.27	1.9e-16	6.082	7.3	2.1e-13	0.74	0.57	0.43	FALSE
15	GTEx	Heart Left Ventricle	C1GALT1	0.17	0.04	enet	23	0.05	1.5e-03	7.278	7.3	2.1e-13	0.69	0.02	0.94	FALSE
16	GTEx	Lung	C1GALT1	0.18	0.13	lasso	3	0.15	1.1e-11	6.082	8.1	4.8e-16	0.80	0.01	0.99	FALSE
17	GTEx	Nerve Tibial	C1GALT1	0.44	0.28	lasso	12	0.40	2.0e-30	5.167	7.4	1.1e-13	0.76	0.97	0.03	FALSE
18	GTEx	Ovary	C1GALT1	0.22	0.14	enet	11	0.15	1.8e-04	6.476	7.0	3.7e-12	0.81	0.10	0.61	FALSE
19	GTEx	Pancreas	C1GALT1	0.44	0.11	enet	24	0.22	8.8e-10	5.167	7.2	7.4e-13	0.76	0.11	0.89	FALSE
20	GTEx	Skin Sun Exposed Lower leg	C1GALT1	0.22	0.04	lasso	9	0.10	4.8e-09	6.484	8.0	1.1e-15	0.78	0.02	0.98	FALSE
21	GTEx	Spleen	C1GALT1	0.56	0.29	lasso	6	0.46	3.2e-13	6.906	5.9	3.3e-09	0.70	0.04	0.95	FALSE
22	GTEx	Stomach	C1GALT1	0.24	0.07	enet	17	0.12	1.9e-06	6.906	6.9	4.5e-12	0.75	0.54	0.42	FALSE
23	GTEx	Thyroid	C1GALT1	0.30	0.27	lasso	3	0.31	3.9e-24	5.167	6.9	4.1e-12	0.68	1.00	0.00	FALSE
24	GTEx	Uterus	C1GALT1	0.38	0.28	enet	8	0.32	2.0e-07	6.993	7.3	2.4e-13	0.85	0.09	0.80	FALSE
25	METSIM	Adipose	C1GALT1	0.22	0.16	lasso	9	0.23	5.1e-34	8.041	8.1	5.7e-16	0.85	0.00	1.00	FALSE
26	ROSMAP	Brain Pre-frontal Cortex	C1GALT1	0.24	0.13	lasso	5	0.23	4.6e-29	-0.063	5.5	3.4e-08	0.63	0.69	0.31	FALSE
27	YFS	Blood	C1GALT1	0.35	0.20	enet	45	0.32	4.3e-109	6.082	6.1	1.3e-09	0.64	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1GALT1	0.02	0.01	lasso	4	0.01	1.7e-02	5.159	6.1	1.1e-09	0.52	0.06	0.69	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1GALT1	0.22	0.11	enet	20	0.16	3.4e-18	6.993	5.9	4.5e-09	0.66	0.62	0.38	FALSE
30	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1GALT1	0.16	0.12	lasso	7	0.14	3.7e-08	7.926	8.0	1.2e-15	0.84	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	C1GALT1	0.13	0.06	blup	112	0.10	1.7e-11	8.041	5.3	1.2e-07	0.69	0.00	1.00	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	C1GALT1	0.08	0.03	blup	112	0.06	2.5e-07	-0.750	5.3	1.4e-07	0.63	0.74	0.26	FALSE
33	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C1GALT1	0.27	0.06	enet	22	0.10	8.1e-05	6.903	7.1	9.4e-13	0.58	0.25	0.20	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1GALT1	0.12	0.05	enet	10	0.13	9.9e-14	5.159	6.1	1.2e-09	0.65	0.54	0.46	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	C1GALT1	0.05	0.01	lasso	2	0.01	3.8e-02	7.805	8.1	3.8e-16	0.96	0.00	0.95	FALSE