TWAS
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Traits
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Traits
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Cardiovascular Disease
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chr7:26,871,554-28,401,337
Best TWAS P=5.15e-15 · Best GWAS P=2.09e-17 conditioned to 0.00349
26.8M
27M
27.2M
27.4M
27.6M
27.8M
28M
28.2M
28.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
HOXA10
0.02
0.01
blup
53
0.01
9.0e-03
-8.3
7.8
5.1e-15
-0.85
0
0.85
TRUE
1
GTEx
Muscle Skeletal
HIBADH
0.21
0.18
enet
10
0.22
6.9e-21
5.5
5.6
2.0e-08
-0.06
1
0.00
TRUE