TWAS
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Traits
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Cardiovascular Disease
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chr7:115,619,298-117,135,212
Best TWAS P=1.96e-07 · Best GWAS P=2.08e-07 conditioned to 1
115.6M
115.8M
116M
116.2M
116.4M
116.6M
116.8M
117M
117.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
MET
0.13
0.11
lasso
8
0.10
6.4e-08
5.2
-5.2
2.0e-07
-0.98
0
1
TRUE
1
GTEx
Artery Aorta
MET
0.21
0.23
lasso
5
0.22
3.0e-12
5.2
-5.1
2.8e-07
-0.98
0
1
FALSE