TWAS hub - MET

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0770	0.0240	5.2e-06	0.073	0.048	0.066	0.053	0.072	3.2e-09	1.5e-06	2.0e-08	5.0e-07	4.5e-09
2	GTEx	Artery Aorta	0.2120	0.0510	8.2e-08	0.226	NA	0.193	NA	0.218	1.1e-12	NA	7.2e-11	NA	3.0e-12
3	GTEx	Artery Tibial	0.1321	0.0405	2.3e-06	0.108	NA	0.078	NA	0.095	8.4e-09	NA	1.0e-06	NA	6.4e-08
4	GTEx	Brain Caudate basal ganglia	0.3850	0.0780	6.0e-08	0.346	NA	0.304	NA	0.291	9.4e-11	NA	2.1e-09	NA	5.1e-09
5	GTEx	Brain Putamen basal ganglia	0.2090	0.0750	2.3e-03	0.122	NA	0.004	NA	0.055	8.3e-04	NA	2.5e-01	NA	2.0e-02
6	GTEx	Testis	0.6820	0.0840	3.5e-04	-0.006	NA	-0.006	NA	-0.002	8.0e-01	NA	7.8e-01	NA	4.0e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0686	0.0267	4.7e-04	0.018	0.019	0.019	0.023	0.019	2.2e-03	1.4e-03	1.4e-03	5.5e-04	1.3e-03
8	TCGA	Brain Lower Grade Glioma	0.0587	0.0241	9.6e-08	0.082	0.070	0.078	NA	0.075	1.4e-09	2.1e-08	3.3e-09	NA	7.7e-09
9	TCGA	Prostate Adenocarcinoma	0.0848	0.0338	2.3e-06	0.017	0.065	0.054	NA	0.049	6.4e-03	2.3e-07	2.5e-06	NA	7.6e-06
10	TCGA	Thyroid Carcinoma	0.0520	0.0300	1.8e-03	0.066	0.025	0.058	NA	0.067	5.6e-07	1.6e-03	2.5e-06	NA	4.4e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Pulse rate, automated reading	10.7	34.4	51.8	7.2	-6.1	-6.5	7.1	7.2	0.4	5.2	7.1	-3.3	-4.7
Medication: Atenolol	9.1	11.4	21.8	3.5	-4.7	-4.7	3.7	3.6	-0.4	3.1	3.3	-2.4	-2.4
Pulse rate	7.2	12.1	20.2	4.1	-4.3	-4.5	4.0	4.0	1.5	3.0	3.8	-1.2	-2.6
HDL Cholesterol	6.9	11.5	16.4	-3.8	3.1	3.2	-3.9	-4.1	-1.9	-3.6	-3.7	2.7	3.4
Supplements: Vitamin C	6.6	7.8	14.4	3.0	-3.7	-3.8	2.4	2.9	1.1	3.5	2.8	-2.0	-1.0
Mineral and other dietary supplements	6.5	8.7	14.6	-3.1	3.7	3.8	-2.8	-3.1	0.5	-3.7	-2.7	3.2	0.8
Triglycerides	6.1	10.0	12.4	3.5	-3.2	-3.3	3.4	3.4	0.4	3.2	3.1	-3.3	-3.5
Supplements: Fish oil (including cod liver oil)	6.0	7.9	15.9	2.5	-4.0	-4.0	2.3	2.6	-1.3	3.4	2.3	-3.1	-0.3
Supplements: Zinc	5.9	6.4	15.7	2.5	-2.6	-2.6	2.5	2.4	-4.0	2.7	2.0	-0.7	-2.4
Medication: Simvastatin	5.7	8.4	14.8	3.1	-3.6	-3.9	2.8	2.9	0.5	2.7	2.8	-2.0	-3.2
Medication: Omeprazole	5.6	6.7	10.3	2.8	-2.4	-2.8	2.7	2.9	0.5	2.8	3.2	-2.9	-1.9
Average weekly champagne plus white wine intake	5.1	7.0	11.3	-2.9	2.3	2.7	-2.8	-2.9	-0.8	-2.9	-2.8	3.4	2.1
High cholesterol (Self-reported)	5.0	8.8	19.6	2.9	-4.2	-4.4	2.9	2.8	0.3	2.6	2.9	-1.4	-3.1
Lung FEV1/FVC ratio	4.9	24.8	47.5	5.7	-6.9	-6.6	5.7	6.0	-0.8	3.4	5.1	-2.6	-3.6
Eye problems/disorders: Glaucoma	4.9	5.8	10.2	2.6	-3.2	-3.0	2.8	2.5	-1.0	2.6	2.2	-1.4	-1.6
Cholesterol lowering medication	4.6	6.7	13.4	2.6	-3.4	-3.7	2.6	2.4	1.1	2.3	2.6	-1.9	-2.4
Hypertension (Self-reported)	4.5	12.6	24.7	3.2	-5.0	-4.9	3.6	3.3	-2.5	2.7	3.4	-3.1	-2.8
Hayfever/allergic rhinitis (self-reported)	4.4	5.9	9.9	-2.9	1.7	1.8	-3.1	-3.0	-1.9	-2.8	-2.7	1.4	2.1
Vascular/heart problems diagnosed by doctor	4.2	11.5	23.0	-3.2	4.8	4.8	-3.5	-3.2	1.7	-2.8	-3.4	2.8	2.6
Vitamin and mineral supplements	4.1	5.5	14.1	-2.4	3.8	3.7	-1.9	-2.4	0.6	-2.5	-1.9	1.2	-0.7
Schizophrenia vs Biploar Disorder	4.0	5.2	8.7	-2.7	2.1	2.1	-2.9	-2.9	0.6	-2.1	-2.3	1.9	2.3
High blood pressure	4.0	11.1	22.6	3.0	-4.8	-4.7	3.3	3.0	-2.1	2.6	3.2	-2.9	-2.8
Noisy workplace	4.0	4.9	15.4	2.0	-3.9	-3.8	2.0	2.0	0.1	1.2	1.8	-0.8	-1.4
Cardiovascular Disease	3.9	12.9	27.0	3.4	-5.1	-5.2	3.5	3.4	-1.8	3.1	3.3	-2.9	-2.8
Systolic blood pressure, automated reading	3.8	11.1	24.1	3.0	-3.4	-3.6	3.1	2.9	-0.6	4.9	3.0	-4.9	-1.4
Number of treatments/medications taken	3.7	6.6	11.7	2.6	-3.4	-3.4	2.5	2.6	0.7	2.8	2.5	-2.6	-1.3
Ever highly irritable/argumentative for 2 days	3.6	4.4	8.9	2.1	-3.0	-2.9	2.4	2.1	-0.9	1.4	2.0	-1.4	-1.8
Medication for cholesterol, blood pressure or diabetes	3.6	6.0	12.8	-2.2	3.6	3.4	-2.3	-2.4	0.4	-2.7	-1.6	1.8	2.5
Fluid intelligence score	3.4	7.1	11.4	-2.8	2.0	2.2	-3.0	-2.9	-0.8	-3.3	-3.3	3.4	1.8
Arm fat-free mass (right)	3.4	17.5	27.8	4.2	-5.0	-5.3	4.2	4.2	-2.6	4.5	4.6	-4.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	3.4	4.2	6.5	2.2	-2.1	-2.4	2.0	2.3	0.4	2.2	2.5	-2.2	-1.1
Shortness of breath walking on level ground	3.3	3.9	6.1	1.9	-2.0	-1.9	2.1	2.0	-0.9	2.1	1.8	-2.2	-2.5
Qualifications: College or University degree	3.3	10.4	24.2	-2.6	4.9	4.7	-2.7	-2.7	-1.1	-3.3	-2.3	3.9	1.8
Leg fat mass (right)	3.3	12.8	21.1	4.0	-4.3	-4.6	4.3	4.2	-1.0	2.7	4.2	-2.3	-2.3
Respiratory disease	3.2	7.2	11.4	-2.9	2.6	2.7	-3.4	-3.1	0.2	-2.6	-3.1	1.4	3.1
Leg fat percentage (right)	3.2	11.7	19.8	4.2	-3.4	-3.8	4.5	4.3	-0.1	2.2	4.3	-1.4	-3.2
Commuting to job workplace: Walk	3.2	3.5	6.6	-2.2	1.3	1.3	-2.3	-2.4	0.5	-2.6	-2.2	1.7	0.8
Fractured/broken bones in last 5 years	3.2	4.1	8.5	1.7	-2.9	-2.9	1.8	1.7	0.6	1.7	1.6	-2.5	-1.8
Smoking Status	3.1	7.3	21.5	1.9	-4.6	-4.4	2.3	2.0	-0.3	2.5	2.4	-2.7	0.1
Supplements: Glucosamine	3.1	4.0	7.8	1.8	-2.7	-2.8	1.8	1.7	0.9	2.4	1.4	-2.5	-1.0
Arm predicted mass (right)	3.1	15.9	26.2	3.9	-4.9	-5.1	4.0	3.9	-2.6	4.3	4.3	-4.3	-0.5
Arm predicted mass (left)	3.1	15.9	27.2	3.8	-5.0	-5.2	3.9	3.8	-2.9	4.2	4.3	-4.2	-0.4
Systolic Blood Pressure	3.0	15.1	25.5	3.6	-4.5	-4.6	3.8	3.5	-1.3	4.9	3.5	-5.0	-2.8
Allergy or Eczema	3.0	7.9	15.7	-3.7	2.2	2.4	-4.0	-3.8	-0.1	-1.7	-3.3	0.2	3.1
Asthma	3.0	5.8	8.9	-2.7	1.9	2.2	-3.0	-2.8	0.5	-2.8	-3.0	1.9	2.2
Asthma (self-reported)	3.0	6.1	9.5	-2.8	2.0	2.3	-3.1	-2.9	0.5	-2.8	-3.1	1.9	2.2
Medication: Blood pressure	3.0	5.7	8.7	2.8	-2.6	-2.7	3.0	2.9	-2.0	1.7	2.9	-1.0	-1.7
Arm fat-free mass (left)	3.0	15.2	25.1	3.9	-4.8	-5.0	4.0	3.9	-2.4	4.1	4.3	-4.1	-0.6
Hayfever, allergic rhinitis or eczema	2.9	6.3	12.8	-3.4	1.8	2.0	-3.6	-3.5	-0.4	-1.8	-3.1	0.5	2.6
Qualifications: A levels/AS levels or equivalent	2.9	6.4	16.1	-2.1	4.0	4.0	-2.3	-2.0	-0.2	-2.3	-2.2	2.7	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.9	3.5	4.3	-1.8	1.8	2.0	-2.0	-1.8	1.9	-2.1	-2.0	1.5	1.6
Waist circumference	2.8	10.4	16.1	3.5	-3.8	-4.0	3.8	3.6	-0.7	3.0	3.7	-2.5	-2.0
Leg pain on walking	2.8	3.5	4.9	2.0	-1.9	-1.9	2.1	2.1	-0.2	1.7	2.0	-1.5	-2.2
Impedance of arm (right)	2.7	12.7	20.9	-3.2	4.0	4.2	-3.4	-3.2	3.2	-3.9	-3.7	4.6	1.1
Qualifications: O levels/GCSEs or equivalent	2.7	4.2	6.9	-1.8	2.5	2.6	-2.1	-1.8	-1.7	-2.2	-1.9	1.6	2.1
Leg fat mass (left)	2.7	10.7	19.0	3.5	-4.2	-4.4	3.8	3.7	-0.8	2.5	3.8	-2.3	-1.9
Taking other prescription medications	2.6	4.0	5.9	2.0	-2.3	-2.4	2.2	1.9	-0.3	1.8	2.2	-2.2	-1.9
Medication: Cholesterol lowering	2.6	4.0	7.4	1.8	-2.7	-2.6	1.9	1.9	-0.1	2.5	1.5	-1.5	-2.2
Supplements: Calcium	2.6	2.9	6.6	2.0	-1.5	-1.7	1.8	1.7	0.7	2.6	1.5	-1.2	-1.7
Maternal smoking around birth	2.5	3.6	8.3	1.4	-2.9	-2.9	1.6	1.3	0.8	1.5	1.4	-1.8	-2.2
Multivitamins +/- minerals	2.5	3.2	9.7	1.4	-3.1	-3.0	1.2	1.5	-2.1	1.1	1.0	-0.3	0.9
Tinnitus: Yes, now most or all of the time	2.5	2.9	5.9	1.6	-2.4	-2.3	1.8	1.9	0.3	1.5	1.5	-0.5	-1.9
Qualifications: None of the above	2.4	5.2	11.0	2.0	-3.3	-3.1	2.1	2.2	0.9	2.2	1.8	-2.8	-1.2
Impedance of arm (left)	2.4	11.2	19.6	-2.8	3.8	4.1	-3.0	-2.8	3.4	-3.5	-3.5	4.4	0.3
Medication for pain relief, constipation, heartburn	2.4	4.1	10.4	-2.0	3.2	3.1	-1.8	-2.0	-1.2	-2.0	-1.7	1.2	0.2
Qualifications: NVQ or HND or HNC or equivalent	2.4	2.8	7.3	1.3	-2.0	-2.1	1.4	1.2	-0.5	2.0	1.6	-2.7	-0.9
Depression (Nagel 2018)	2.3	3.4	10.9	0.9	-3.3	-3.0	1.1	1.1	-2.1	1.0	1.1	-2.0	-0.3
Allergy	2.3	5.3	11.0	3.0	-1.2	-1.5	3.3	3.1	-0.5	1.6	2.9	-0.6	-2.9
Weight	2.3	11.2	19.6	3.5	-4.2	-4.4	3.7	3.6	-1.3	3.0	3.9	-2.8	-1.1
Prospective memory result	2.3	2.8	6.3	1.5	-1.1	-1.4	1.8	1.4	-0.8	2.4	2.2	-2.5	0.5
Medication: Blood pressure	2.3	4.1	12.0	1.5	-3.5	-3.1	1.6	1.6	-0.3	1.8	1.2	-2.2	-1.3
Whole body fat mass	2.3	9.8	16.2	3.5	-3.9	-4.0	3.8	3.7	-0.3	2.3	3.7	-1.9	-2.0
Leg fat percentage (left)	2.3	8.2	13.6	3.3	-3.2	-3.4	3.7	3.5	0.1	1.9	3.5	-1.4	-2.4
Past tobacco smoking	2.2	4.0	13.7	-1.2	3.7	3.5	-1.5	-1.2	-1.0	-1.9	-1.2	1.7	0.2
Body mass index (BMI)	2.1	8.8	14.4	3.1	-3.6	-3.8	3.5	3.2	-1.1	2.4	3.5	-2.5	-1.8
Number of full brothers	2.1	2.6	4.1	1.7	-1.8	-1.8	1.7	1.7	0.0	2.0	1.5	-1.7	-1.3
Medication for cholesterol	2.1	3.1	6.4	-1.9	2.4	2.5	-1.8	-1.8	1.1	-1.2	-2.0	1.4	0.6
Smoking status: Current	2.1	3.3	7.7	1.3	-2.8	-2.8	1.6	1.4	-0.6	1.7	2.0	-2.1	0.2
Financial situation satisfaction	2.1	2.6	7.3	0.9	-2.7	-2.7	1.0	0.8	-2.0	1.0	1.1	-1.7	0.2
Heart disease (siblings)	2.1	2.6	5.0	1.8	-2.1	-2.2	1.6	1.7	1.4	1.0	1.4	-0.4	-1.4
Glaucoma (self-reported)	2.0	2.4	6.6	1.5	-2.6	-2.3	1.6	1.3	-0.4	1.4	1.2	-1.2	-0.7
Neck or shoulder pain in last month	2.0	2.9	10.6	0.9	-2.0	-2.0	0.8	0.9	1.0	2.2	1.1	-3.3	-0.9
Whole body fat-free mass	2.0	11.2	21.3	3.0	-4.5	-4.6	3.0	3.0	-2.9	3.5	3.3	-3.5	0.3
Basal metabolic rate	2.0	11.1	21.5	3.1	-4.5	-4.6	3.1	3.1	-2.6	3.3	3.4	-3.3	0.0
Coronary Artery Disease (CAD)	1.9	2.3	5.6	1.3	-2.2	-2.1	1.1	1.2	2.4	1.0	0.8	-1.1	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.6	7.4	1.2	-2.7	-2.7	1.3	1.3	-1.7	0.5	1.5	-1.0	-0.3
Qualifications: CSEs or equivalent	1.9	2.5	7.8	-1.2	1.2	1.2	-1.6	-1.5	0.8	-1.9	-1.4	1.1	2.8
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	5.5	-2.4	2.0	2.2	-2.3	-2.2	-1.3	-2.0	-2.3	1.6	2.3
Trunk fat-free mass	1.9	11.1	20.7	3.0	-4.4	-4.5	3.0	3.0	-2.9	3.5	3.3	-3.5	0.3
Trunk predicted mass	1.9	11.1	20.4	3.0	-4.3	-4.5	3.0	3.0	-2.9	3.5	3.4	-3.5	0.4
Blood Platelet Count	1.8	21.2	41.0	-6.4	-0.6	-0.1	-6.4	-6.3	2.9	-1.8	-5.5	-2.9	6.4
Chronotype (morning person)	1.8	4.1	6.5	-2.2	2.3	2.2	-2.1	-2.2	-2.3	-2.6	-1.8	1.0	0.7
Current tobacco smoking	1.8	3.0	7.5	1.2	-2.7	-2.7	1.6	1.3	-0.2	1.6	1.8	-2.0	-0.2
Trunk fat mass	1.8	7.8	13.2	3.1	-3.5	-3.6	3.4	3.3	0.2	2.0	3.3	-1.5	-1.8
Arm fat mass (right)	1.8	7.3	13.9	2.9	-3.6	-3.7	3.1	3.0	-0.7	1.9	3.2	-1.9	-1.3
Age at first live birth	1.8	3.1	4.8	-1.9	2.0	2.2	-1.9	-1.9	0.3	-1.8	-1.7	2.1	1.2
Whole body water mass	1.8	10.5	20.5	2.9	-4.4	-4.5	2.9	2.8	-2.7	3.3	3.2	-3.4	0.4
Pain type(s) experienced in last month: Hip pain	1.8	2.2	4.9	-2.1	-0.0	0.0	-2.1	-2.2	1.3	-1.4	-1.7	0.0	1.4
Ulcerative Colitis	1.7	2.5	5.3	-2.3	0.6	1.0	-2.1	-2.1	0.4	-1.1	-2.3	1.2	1.2
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	7.0	1.1	-2.6	-2.6	1.3	1.1	-0.7	0.7	1.1	-0.6	-0.3
Hip circumference	1.7	7.1	11.5	3.0	-2.8	-3.1	3.2	3.0	-1.3	2.4	3.4	-2.1	-1.5
Medication: Ventolin 100micrograms inhaler	1.7	2.1	3.5	-1.8	1.5	1.7	-1.9	-1.7	1.4	-1.0	-1.8	-0.2	1.0
Health satisfaction	1.7	2.2	4.4	1.7	-2.1	-2.0	1.5	1.6	0.7	0.9	1.3	-1.2	-1.3
Diabetes diagnosed by doctor	1.7	2.9	9.7	1.2	-3.1	-2.9	1.6	1.2	-1.1	0.2	1.2	-0.4	-1.4
Number of operations (self-reported)	1.7	2.5	5.0	1.7	-1.6	-1.7	1.8	1.8	-0.1	1.0	1.7	-1.0	-2.2
Medication for hormone replacement therapy	1.6	1.7	4.8	-1.4	0.7	0.9	-1.5	-1.4	-2.2	-1.5	-1.2	-0.0	1.0
Hearing difficulty/problems with background noise	1.6	2.5	9.3	1.1	-3.1	-2.7	1.4	1.3	0.2	1.0	0.8	0.1	-1.3
Hair/balding pattern: Pattern 3	1.6	2.4	5.8	1.5	-1.0	-1.1	1.5	1.4	-1.1	2.4	1.6	-2.1	-1.0
Medication: Amlodipine	1.6	2.2	5.8	0.3	-2.4	-2.3	0.6	0.2	-1.9	1.4	0.6	-2.0	0.7
Medication: Aspirin	1.6	2.1	4.6	1.4	-2.1	-2.1	1.5	1.3	-0.2	1.4	1.1	-0.8	-1.5
Intelligence (Savage-Jansen 2018)	1.5	4.6	7.0	-2.2	2.3	2.5	-2.4	-2.3	0.1	-2.0	-2.5	2.6	1.4
Body Mass Index (BMI) (2010)	1.5	2.1	3.6	1.4	-1.8	-1.9	1.6	1.5	-1.0	0.8	1.9	-1.4	-0.3
LDL Cholesterol	1.5	2.3	4.9	1.7	-0.8	-1.1	1.6	1.5	-1.2	2.0	1.8	-2.2	-0.7
Had other major operations	1.5	1.9	4.0	2.0	-0.6	-0.9	1.8	1.9	-0.3	-0.0	1.7	0.1	-1.9
Pain all over the body in last month	1.5	1.6	6.9	-1.3	-0.2	0.1	-1.3	-1.2	-2.6	-1.0	-1.6	0.5	0.3
Illnesses of siblings	1.5	2.1	4.3	-1.5	1.6	1.7	-1.1	-1.4	-0.4	-1.8	-1.0	2.1	1.3
Body fat percentage	1.5	5.8	9.6	2.8	-2.5	-2.7	3.1	3.0	0.8	1.3	3.0	-0.8	-2.3
Overall health rating	1.5	3.2	8.7	1.4	-2.9	-2.9	1.3	1.5	1.1	1.4	1.4	-1.9	-0.8
Smoking status: Previous	1.5	2.3	9.6	0.6	-3.1	-2.8	0.9	0.6	1.2	1.2	0.4	-0.9	-0.2
Osteoporosis (self-reported)	1.5	1.8	3.4	-1.5	0.9	0.9	-1.8	-1.7	1.7	-0.6	-1.6	-0.6	1.4
Number of self-reported non-cancer illnesses	1.5	2.6	5.0	1.6	-2.2	-2.2	1.6	1.5	-1.6	0.6	1.4	-1.0	-1.6
Ever smoked	1.5	2.5	8.0	1.1	-2.8	-2.7	1.3	1.1	1.1	1.6	1.0	-1.2	0.2
Neuroticism (2016)	1.4	2.0	5.4	-1.6	-0.4	-0.2	-1.6	-1.7	-0.6	-2.3	-1.9	1.4	1.0
Leg fat-free mass (left)	1.4	7.3	15.4	2.4	-3.8	-3.9	2.4	2.4	-2.4	2.5	2.7	-2.6	0.3
Diabetes (self-reported)	1.4	2.2	8.4	1.0	-2.9	-2.7	1.3	0.9	-0.9	-0.4	0.9	0.2	-1.2
Arm fat mass (left)	1.4	5.9	11.3	2.6	-3.2	-3.4	2.8	2.7	-0.6	1.6	2.9	-1.7	-1.3
Myopia	1.4	2.0	3.8	-1.8	-0.1	0.0	-1.9	-1.8	-0.8	-1.9	-1.6	-0.1	1.7
Average weekly spirits intake	1.3	1.7	3.8	0.8	-1.8	-1.9	0.5	0.6	-0.1	1.4	0.9	-1.9	1.3
Medication: Metformin	1.3	1.8	6.8	1.1	-2.6	-2.4	1.1	1.0	-1.1	-0.2	0.7	0.5	-0.8
Trunk fat percentage	1.3	5.3	8.8	2.7	-2.5	-2.6	3.0	2.9	1.1	1.3	2.8	-0.6	-2.2
Serious illness, injury or assault to yourself	1.3	1.6	3.6	-1.9	0.8	1.0	-1.7	-1.8	-0.3	-0.8	-1.7	-0.9	0.5
Leg predicted mass (left)	1.3	7.1	14.8	2.3	-3.7	-3.9	2.3	2.3	-2.5	2.5	2.6	-2.6	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	2.9	1.5	-1.1	-1.2	1.4	1.4	-1.1	1.3	1.7	-1.1	-0.4
Breast Cancer	1.2	2.9	6.3	2.3	-1.4	-1.4	2.1	2.2	-2.5	0.4	1.9	-0.4	-0.6
Schizophrenia (2014)	1.2	2.6	11.1	-0.7	2.2	2.1	-0.8	-0.8	3.3	-0.6	-0.6	1.7	0.5
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.7	1.2	-0.8	-1.0	1.6	1.3	-0.3	1.0	1.4	0.2	-1.5
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.4	1.2	-1.8	-1.7	1.1	1.1	0.0	0.9	0.6	-0.6	-1.6
Chronic bronchitis/emphysema (father)	1.2	1.4	2.4	-1.4	0.8	0.9	-1.4	-1.5	-1.4	-1.5	-1.4	0.6	0.2
Number of live births	1.2	1.7	3.4	0.8	-1.6	-1.6	1.0	1.0	1.3	1.8	0.9	-1.5	-0.9
Loud music exposure frequency	1.2	1.3	6.0	0.4	-2.4	-2.2	0.5	0.4	-0.6	0.3	0.6	-0.2	0.9
Blood clot in the leg (DVT)	1.2	1.5	3.5	1.3	-0.6	-0.6	1.2	1.4	-1.3	1.2	1.2	-1.9	-1.0
Number of full sisters	1.2	1.4	2.4	1.5	-0.9	-1.0	1.3	1.5	1.6	0.8	1.4	-0.9	-0.8
Chest pain or discomfort	1.2	1.7	6.4	0.1	-2.1	-2.1	0.2	0.1	-0.3	1.2	0.4	-2.5	-0.1
Age at last live birth	1.2	1.8	3.3	-1.5	1.1	1.3	-1.3	-1.4	1.3	-1.3	-1.4	1.8	0.8
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	5.2	-0.7	2.3	2.1	-0.9	-0.8	1.0	-1.7	-0.5	1.8	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	3.4	1.2	-1.7	-1.6	0.9	1.0	-1.9	0.6	1.1	-0.9	-0.3
Impedance of whole body	1.2	6.2	12.1	-1.4	3.3	3.4	-1.5	-1.3	3.3	-2.5	-2.0	3.5	-0.6
Crohns Disease (2012)	1.1	1.8	4.0	1.4	-2.0	-1.8	1.4	1.5	0.4	0.9	0.8	0.5	-1.7
Heel T-Score	1.1	9.0	16.4	-3.3	3.8	4.0	-2.8	-3.2	-0.3	-3.6	-2.8	2.9	1.1
Type 2 Diabetes (T2D) (2018)	1.1	2.0	9.8	0.7	-3.1	-2.7	0.9	0.7	-1.0	-0.2	0.4	-0.0	-0.4
Illnesses of mother	1.1	1.4	5.4	-0.4	1.6	1.6	-0.6	-0.5	-0.3	-1.6	-0.5	2.3	0.3
Qualifications: nursing, teaching	1.1	1.7	6.2	-0.4	2.5	2.4	-0.6	-0.4	-1.5	-1.0	-0.8	1.1	-0.1
Unable to work because of sickness or disability	1.1	1.5	5.4	-0.1	-2.3	-2.0	0.2	0.0	-0.3	0.6	-0.1	-1.5	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.2	1.2	-0.3	-0.4	1.0	1.3	-1.4	1.3	1.1	-2.0	-0.8
Verbal and Numeric Reasoning (VNR)	1.0	2.4	6.4	-1.4	1.5	1.6	-1.5	-1.4	-1.1	-1.4	-1.6	2.5	1.1
Age at First Birth	1.0	1.5	4.5	0.4	2.1	1.9	0.2	0.4	0.1	-0.7	0.1	2.0	-1.4
BMI	1.0	5.5	9.2	2.8	-2.7	-2.9	2.9	2.9	-1.2	1.3	3.0	-1.5	-0.6
Hand grip strength (left)	1.0	2.6	8.7	1.4	0.7	0.5	1.2	1.5	-1.8	2.2	1.4	-3.0	-0.5
Hearing difficulty/problems: Yes	1.0	1.5	3.3	1.4	-0.8	-1.0	1.5	1.4	1.0	0.7	1.3	0.3	-1.8
Ever had hysterectomy (womb removed)	1.0	1.1	2.5	0.9	-0.5	-0.7	1.0	0.9	0.7	1.6	1.2	-1.5	-1.2
Angina	1.0	1.3	3.6	0.9	-1.9	-1.9	1.0	0.9	-0.4	1.2	1.0	-0.8	0.5
Medication: Co-codamol	1.0	1.2	2.6	1.0	-0.7	-0.6	1.0	1.1	0.5	1.5	0.9	-1.6	-1.5
Medication: Lansoprazole	1.0	1.1	3.2	0.9	-1.0	-0.8	0.7	0.8	1.1	0.6	0.6	-1.8	-1.5
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	6.0	-0.8	2.4	2.3	-0.9	-0.8	0.5	-1.7	-0.5	1.5	-0.0
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.4	-1.5	0.8	0.8	-1.6	-1.5	-0.6	-0.3	-1.2	-0.3	1.3
Heart disease (mother)	1.0	1.2	3.5	0.8	-1.8	-1.9	0.5	0.6	-0.0	1.3	0.6	-1.1	0.8
Family relationship satisfaction	1.0	1.3	2.7	-0.9	1.4	1.4	-1.3	-1.0	-0.2	-1.1	-1.1	0.3	1.6
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.2	-0.7	1.7	1.8	-0.9	-0.8	0.5	0.1	-0.9	1.2	1.3
Ever taken oral contraceptive pill	1.0	1.1	3.0	0.8	-0.6	-0.9	1.0	0.9	1.7	1.0	1.4	-1.2	-0.4
Risk taking	1.0	1.4	10.4	-0.1	-1.2	-0.9	-0.0	0.0	-3.2	-0.1	-0.1	-0.4	1.3
Pack years of smoking	1.0	1.5	5.3	1.0	-2.3	-2.1	1.0	0.9	-0.2	0.7	0.5	0.2	-1.1
Ulcerative Colitis (UC)	0.9	1.7	3.7	-1.9	0.5	0.7	-1.5	-1.7	-0.9	-1.4	-1.4	0.9	1.1
Major Depression (MDD)	0.9	1.1	3.4	-0.6	-1.9	-1.6	-0.3	-0.6	-1.8	-0.3	-0.8	-0.5	-0.4
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.0	0.4	1.3	1.3	-0.0	-0.2	0.9	-1.4	-0.5	1.4	-1.4
Fed-up feelings	0.9	1.7	4.1	1.2	-2.0	-2.0	1.2	1.3	-1.6	-0.2	1.1	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.6	-0.9	-0.1	-0.0	-1.3	-1.0	-0.3	-1.6	-1.0	0.8	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	5.2	0.4	-2.2	-2.3	0.6	0.4	-0.9	0.9	0.8	-1.2	-0.3
Falls in the last year	0.9	1.2	3.3	0.9	-1.1	-1.2	1.2	1.0	0.9	0.6	0.9	-1.0	-1.8
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.0	1.2	-1.4	-1.3	1.0	1.2	1.4	1.0	0.8	0.1	0.6
Birth weight of first child	0.9	1.6	4.9	0.5	-2.2	-2.0	0.8	0.6	-1.1	1.2	0.9	-1.2	0.7
Wheeze or whistling in the chest in last year	0.9	1.5	3.1	1.0	-1.7	-1.8	1.0	1.0	0.8	1.1	1.3	-1.6	0.0
Number of children fathered	0.9	1.0	7.8	0.2	-0.2	-0.4	0.1	0.1	2.8	1.2	0.5	-0.7	0.2
Leg fat-free mass (right)	0.9	5.0	10.9	1.5	-3.3	-3.3	1.6	1.5	-2.4	2.1	1.9	-2.5	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	3.1	-1.6	1.1	1.3	-1.7	-1.4	0.7	-1.8	-1.7	1.1	1.0
Leg predicted mass (right)	0.9	4.9	10.8	1.5	-3.3	-3.3	1.5	1.5	-2.4	2.1	1.9	-2.5	1.1
Guilty feelings	0.9	1.4	2.9	1.2	-1.7	-1.7	1.4	1.2	-0.7	0.9	1.2	-0.5	-0.0
Medication: Bendroflumethiazide	0.9	1.4	2.9	1.3	-1.7	-1.6	1.3	1.2	-1.2	1.1	0.7	-0.3	-0.4
Sensitivity / hurt feelings	0.8	1.3	4.2	0.8	-2.0	-2.1	1.0	0.6	-1.2	-0.1	0.9	-0.5	-0.6
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.6	1.0	-1.2	-1.3	0.9	1.0	-1.1	1.0	1.0	-1.0	-0.5
Hand grip strength (right)	0.8	2.2	4.6	1.5	1.4	1.0	1.1	1.5	-1.5	2.0	1.4	-2.1	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	2.5	-1.6	0.9	1.1	-1.4	-1.4	-1.6	-1.6	-1.5	1.4	1.1
Hair/balding pattern: Pattern 2	0.8	1.0	1.8	-1.0	1.0	1.0	-1.1	-1.0	-0.6	-0.9	-1.0	1.0	1.3
Had menopause	0.8	1.0	1.9	1.2	-1.1	-1.0	1.4	1.3	0.2	1.0	1.2	0.0	-1.0
Length of working week for main job	0.8	0.9	1.9	-1.4	-0.2	-0.0	-1.3	-1.2	0.2	-0.6	-1.3	0.5	1.2
Breastfed as a baby	0.8	0.9	4.3	-0.9	-0.3	0.0	-0.7	-0.6	-0.7	-0.4	-0.8	1.4	2.1
Emphysema/chronic bronchitis	0.8	0.9	2.3	0.4	-0.9	-0.9	0.5	0.5	1.5	1.3	0.8	-1.1	0.3
Illnesses of siblings: Diabetes	0.8	1.0	3.2	0.6	-1.8	-1.7	0.7	0.7	0.3	0.7	0.5	-1.0	-1.0
Loneliness, isolation	0.8	1.2	4.9	0.0	1.2	1.2	-0.1	0.1	-2.2	-1.2	-0.1	1.5	0.5
Long-standing illness, disability or infirmity	0.8	1.2	3.4	0.4	-1.8	-1.8	0.2	0.2	0.2	1.1	0.3	-1.9	-0.8
Eye problems/disorders: Cataract	0.8	1.0	3.1	0.2	1.8	1.6	-0.3	0.2	0.5	-0.5	-0.2	1.7	0.7
Back pain experienced in last month	0.8	1.2	2.7	-1.5	-0.4	-0.3	-1.6	-1.5	1.1	-0.4	-1.4	0.4	1.0
Medication: Aspirin	0.8	1.0	2.5	0.8	-1.5	-1.6	0.8	0.7	0.1	1.2	0.6	-1.0	-0.7
Illnesses of father: None of the above (group 1)	0.8	1.0	3.5	0.7	0.5	0.5	0.9	1.0	0.2	1.9	1.2	-1.3	0.9
Medication: Paracetamol	0.8	1.2	1.9	1.1	-1.4	-1.3	1.0	1.2	1.2	1.3	1.0	-1.0	-0.4
Schizophrenia (2018)	0.7	1.5	5.6	-0.0	2.1	1.8	-0.1	-0.2	2.4	-0.2	0.4	1.1	-0.1
Alzheimer’s Disease (in mother)	0.7	0.8	3.1	0.8	-0.8	-0.7	1.1	1.1	0.6	0.3	0.7	-0.0	-1.8
Alzheimer’s Disease (in father)	0.7	0.8	2.5	0.4	-1.6	-1.6	0.4	0.3	-1.2	0.3	0.2	-1.0	0.1
Bipolar Disorder (2011)	0.7	0.7	2.9	0.5	-1.1	-0.9	0.6	0.4	-0.2	1.7	0.4	-1.0	0.0
HbA1C	0.7	0.8	1.5	1.1	-0.3	-0.3	1.0	1.1	0.3	0.9	0.8	-1.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.1	-1.4	-0.4	-0.2	-1.4	-1.4	-0.4	-0.6	-1.5	-0.2	0.5
Diabetes (father)	0.7	0.9	4.8	0.0	-0.8	-0.6	0.4	0.0	-2.2	0.7	0.0	-1.4	-0.8
Forced vital capacity (FVC)	0.7	2.7	6.4	-1.8	1.0	1.2	-2.1	-1.9	-1.1	-1.2	-1.9	0.7	2.5
Financial difficulties in last 2 years	0.7	0.9	3.4	0.2	-1.8	-1.8	0.2	0.1	-0.9	0.0	0.3	-1.1	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.4	-0.8	-1.5	-1.2	-0.6	-0.6	-0.9	-1.0	-0.7	1.1	1.5
Mouth/teeth dental problems: Dentures	0.7	1.3	4.5	0.4	-2.1	-2.0	0.4	0.5	0.8	1.4	0.3	-0.8	-0.4
Pulse wave reflection index	0.7	0.8	1.6	-1.1	0.3	0.5	-1.2	-1.3	-0.9	-0.6	-1.3	0.7	0.6
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.8	-1.1	0.7	0.6	-1.0	-1.1	1.1	-1.3	-0.7	0.7	0.6
Ever had bowel cancer screening	0.7	0.8	3.7	0.5	-1.9	-1.8	0.3	0.5	-0.5	0.5	0.2	-0.1	-0.7
Bipolar Disorder or Schizophrenia	0.6	1.5	5.7	0.5	2.0	1.6	0.7	0.4	2.4	0.5	1.1	0.3	-0.7
Prostate Cancer	0.6	0.8	3.4	-0.8	0.0	0.1	-0.7	-0.9	-0.4	-1.0	-0.8	1.8	1.1
Mean Putamen Volume	0.6	0.7	1.5	-1.1	-0.3	-0.0	-1.0	-0.9	0.6	-0.4	-1.1	-0.7	1.2
Blood White Count	0.6	4.5	8.9	-3.0	-0.2	-0.1	-2.7	-3.0	1.7	-1.0	-2.3	-1.4	2.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.0	-0.1	-1.7	-1.5	0.0	-0.0	-1.4	-0.5	0.3	-0.6	0.4
Severe depression (siblings)	0.6	0.6	1.0	0.9	-1.0	-0.9	1.0	1.0	0.0	-0.2	0.6	0.8	-0.8
Pack years adult smoking proportion	0.6	0.9	4.0	0.6	-2.0	-1.9	0.6	0.5	-0.5	0.3	0.2	0.3	-0.5
Heart attack	0.6	0.8	2.6	-0.6	-1.1	-1.0	-0.6	-0.5	0.8	0.9	-0.7	0.1	1.6
Angina (self-reported)	0.6	0.7	2.0	0.6	-1.3	-1.4	0.7	0.6	-0.2	0.9	0.8	-0.7	0.7
Migraine (self-reported)	0.6	0.8	2.1	-0.6	1.1	1.1	-0.4	-0.4	0.6	-1.2	-0.3	1.4	0.7
Arm fat percentage (left)	0.6	2.2	3.9	1.6	-1.9	-2.0	1.9	1.8	0.6	0.2	1.8	-0.1	-1.3
Medication: Atorvastatin	0.6	0.7	2.0	0.6	-1.4	-1.4	0.9	0.7	0.2	0.1	0.6	0.7	-0.8
Average weekly beer plus cider intake	0.6	0.9	2.9	-0.8	-0.6	-0.5	-0.7	-0.9	1.3	-0.8	-0.8	-0.6	1.7
Ever depressed for a whole week	0.6	0.7	1.6	-0.8	-0.3	-0.1	-0.6	-0.7	-1.2	-0.7	-0.9	1.3	0.9
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.0	-0.1	-1.4	-1.3	-0.1	-0.0	1.0	1.2	-0.3	0.0	1.1
Bipolar Disorder (2018)	0.5	0.9	1.9	0.8	0.5	0.3	1.1	0.9	0.9	1.0	1.4	-0.9	-1.0
Crohns Disease (2017)	0.5	1.1	3.0	1.1	-1.1	-1.1	1.3	1.2	0.2	-0.0	1.0	0.7	-1.7
Height	0.5	8.9	24.0	2.3	-4.9	-4.7	1.9	2.3	-0.0	3.8	2.1	-2.7	1.4
Townsend deprivation index at recruitment	0.5	0.8	3.1	-0.8	-0.4	-0.3	-0.6	-0.8	0.4	-1.8	-0.4	1.2	0.9
Average weekly fortified wine intake	0.5	0.5	1.3	-1.1	0.2	0.2	-1.1	-1.0	0.8	-0.3	-0.8	-0.2	0.4
Relative age voice broke	0.5	0.8	2.8	-0.0	1.2	1.3	0.1	0.3	1.7	-0.1	-0.3	1.0	-0.9
Medication: Levothyroxine sodium	0.5	0.9	2.1	-0.1	1.5	1.3	0.0	0.0	1.0	-1.2	0.5	1.4	-0.5
Neuroticism score	0.5	1.0	4.6	-0.8	-1.1	-0.9	-0.8	-0.8	-0.5	-2.1	-0.8	0.8	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	3.1	-0.1	0.5	0.4	-0.4	-0.2	-0.8	-1.7	0.1	1.1	0.8
Medication: Paracetamol	0.5	0.9	1.9	0.8	-1.3	-1.2	0.8	0.9	1.4	0.8	0.7	-0.5	0.1
Exposure to tobacco smoke outside home	0.5	0.7	1.7	0.8	-1.3	-1.3	0.8	0.7	-0.2	-0.1	1.1	-0.8	0.3
Comparative body size at age 10	0.5	1.5	3.4	0.3	-1.8	-1.8	0.4	0.3	0.3	0.9	1.0	-1.5	1.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.5	-0.5	-1.1	-0.9	-0.7	-0.6	-1.2	-0.2	-0.9	-1.0	-0.1
Pulse wave peak to peak time	0.5	0.5	2.2	-0.5	-0.5	-0.5	-0.3	-0.5	-0.3	0.3	0.1	-1.4	1.5
Medication: Seretide 50 evohaler	0.5	0.5	1.6	-0.5	1.3	1.2	-0.7	-0.6	0.7	-0.0	-0.7	-0.4	-0.5
Suffer from ‘nerves’	0.5	0.8	3.8	-0.5	-0.8	-0.7	-0.7	-0.5	-1.2	-1.9	-0.3	0.4	0.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.0	0.9	-0.7	-0.7	0.8	1.0	-0.3	1.0	0.8	-0.8	-0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	-0.8	0.4	0.5	-0.9	-0.9	-0.0	-0.8	-0.5	0.6	1.4
Wears glasses or contact lenses	0.5	0.6	2.8	0.1	-0.7	-0.6	0.3	0.2	-1.1	0.8	-0.0	-0.2	-1.7
Hearing aid user	0.5	0.5	3.4	-0.0	0.5	0.5	0.1	-0.1	1.8	-0.2	-0.0	1.2	-0.2
Commuting to job workplace: Public transport	0.5	0.6	1.5	-0.4	1.1	1.1	-0.0	-0.4	-1.2	-1.0	-0.1	0.8	-0.7
Commuting to job workplace: Cycle	0.5	0.6	1.5	0.4	1.1	1.0	0.1	0.2	-1.0	-0.7	0.1	1.2	0.4
Neuroticism (Nagel 2018)	0.4	1.0	3.0	0.8	-1.7	-1.7	0.7	0.8	-0.8	-0.4	0.6	-0.6	-0.8
Fasting Glucose	0.4	0.5	2.0	-0.4	-0.3	-0.2	-0.6	-0.8	-0.1	0.1	-0.6	-1.4	-1.0
Hypothyroidism (self reported)	0.4	0.9	4.2	-0.2	2.0	1.7	-0.3	-0.1	0.7	-0.3	0.2	0.8	-0.7
Neuroticism	0.4	0.9	2.9	-0.2	-1.7	-1.4	-0.4	-0.3	-0.1	-1.7	-0.5	0.6	0.1
Relative age of first facial hair	0.4	0.9	2.3	0.2	1.1	1.2	0.4	0.5	1.4	-0.2	-0.1	1.5	-1.2
Diabetes (mother)	0.4	0.5	1.1	0.1	-1.1	-1.0	0.1	0.1	-0.9	0.5	0.4	-1.0	0.4
Impedance of leg (right)	0.4	1.8	4.5	1.1	1.2	1.1	0.9	1.1	1.7	-0.8	0.5	2.1	-2.1
Impedance of leg (left)	0.4	1.9	5.5	-0.1	1.7	1.8	-0.2	-0.0	1.9	-1.5	-0.6	2.3	-1.0
Alcohol usually taken with meals	0.4	0.7	2.7	-0.1	1.4	1.2	-0.1	-0.2	-0.5	-0.3	-0.0	1.6	0.2
Arm fat percentage (right)	0.4	1.8	3.7	1.4	-1.8	-1.9	1.6	1.5	0.6	0.1	1.6	-0.1	-0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.2	-1.1	-0.0	0.3	-1.3	-1.1	-1.6	-1.0	-1.3	0.5	2.1
Lung cancer (father)	0.4	0.4	2.8	0.3	-0.4	-0.4	0.3	0.3	1.7	-0.3	0.5	0.4	0.6
Pulse wave Arterial Stiffness index	0.4	0.5	2.0	0.7	0.3	0.3	0.4	0.6	0.2	-0.3	0.1	1.3	-1.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.7	-0.2	-0.2	0.7	0.8	0.6	0.8	0.6	-1.1	-0.7
Gout (self-reported)	0.4	0.5	2.2	-0.6	1.5	1.4	-0.3	-0.5	0.3	0.2	-0.2	-0.4	-0.1
Forced vital capacity (FVC), Best measure	0.4	1.3	5.8	-1.1	0.0	0.2	-1.3	-1.2	-1.3	-0.6	-1.0	0.3	2.4
Eye problems/disorders: None of the above	0.4	0.5	1.6	0.2	-1.3	-1.2	0.2	0.2	-0.4	-0.2	0.3	-1.2	-0.1
Medication: Ibuprofen	0.4	0.4	1.9	0.7	-0.1	-0.1	0.5	0.7	1.4	0.6	0.3	0.5	0.6
Alcohol intake frequency.	0.4	1.0	2.9	1.4	-0.2	-0.3	1.4	1.3	-0.1	-0.7	1.2	-0.0	-1.7
Comparative height size at age 10	0.4	2.3	4.5	1.2	-2.1	-2.1	0.9	1.1	-1.1	1.6	1.6	-1.5	1.4
Had major operations	0.4	0.5	1.7	0.6	-0.3	-0.4	0.9	0.7	0.5	1.3	0.8	0.0	-0.8
Knee pain experienced in last month	0.4	0.6	1.8	-0.3	-1.3	-1.1	-0.3	-0.4	-0.1	0.8	-0.4	-1.3	0.5
Breast cancer (self-reported)	0.4	0.4	1.2	-0.5	1.0	1.1	-0.4	-0.4	0.8	-0.5	-0.4	0.5	-0.5
Miserableness	0.4	0.7	1.9	0.6	-1.4	-1.4	0.6	0.7	-0.6	-1.0	0.6	0.2	-0.4
Medication: Lisinopril	0.4	0.6	1.0	0.8	-0.7	-0.8	1.0	0.7	-0.9	0.7	0.9	-0.6	-0.4
Basal cell carcinoma (self-reported)	0.4	0.5	1.8	0.4	-0.2	-0.4	0.5	0.4	0.4	1.3	0.8	-1.2	0.2
Worry (Nagel 2018)	0.3	0.6	2.0	-0.3	-1.1	-0.9	-0.6	-0.4	0.7	-1.4	-0.6	0.2	0.6
Alzheimer’s Disease (including proxy)	0.3	0.5	1.8	0.1	-1.3	-1.2	0.4	0.2	-0.3	-0.2	0.2	-0.2	-1.0
Ovarian Cancer	0.3	0.4	1.1	0.4	-1.0	-1.0	0.5	0.3	-0.3	0.2	0.2	0.4	-1.1
Lupus	0.3	0.4	1.2	0.3	0.3	0.4	0.4	0.3	-1.0	-0.3	-0.0	1.0	-1.1
Rheumatoid Arthritis	0.3	0.4	2.3	-0.7	0.0	0.1	-0.8	-0.6	0.2	0.2	-0.4	-0.5	1.5
Lung FVC	0.3	1.7	3.8	-1.6	0.7	0.7	-1.6	-1.7	-1.9	-0.5	-1.4	0.3	1.5
Sitting height	0.3	2.1	4.0	0.9	-2.0	-1.9	0.6	0.9	-0.2	1.8	1.2	-1.9	1.8
High blood pressure (mother)	0.3	0.4	0.9	-0.6	-1.0	-0.9	-0.3	-0.6	-0.7	-0.2	-0.6	-0.7	-0.2
Number of incorrect matches in round	0.3	0.4	2.1	-0.1	0.9	0.8	-0.4	-0.2	-1.4	-0.5	-0.1	-0.4	0.4
Medication: Ramipril	0.3	0.4	1.2	-0.2	-1.1	-0.6	-0.1	0.0	-1.0	-0.3	-0.7	-0.2	-0.7
Alcohol intake versus 10 years previously	0.3	0.4	2.3	-0.2	-0.0	0.1	-0.5	-0.3	0.8	-1.5	-0.8	0.6	0.4
Father’s age at death	0.3	0.4	0.8	0.6	0.9	0.8	0.6	0.7	-0.9	0.6	0.5	0.6	0.1
Happiness	0.3	0.4	1.3	0.8	1.1	0.8	0.4	0.5	0.1	-0.0	0.8	-0.3	0.3
Depression (self-reported)	0.3	0.4	1.0	0.3	-1.0	-0.8	0.5	0.4	-0.9	-0.1	0.1	0.7	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	3.1	-0.1	-1.2	-1.0	-0.2	-0.1	-1.8	-0.1	-0.1	-0.2	1.5
Standing height	0.3	2.8	6.0	1.6	-2.4	-2.4	1.2	1.6	-0.8	2.0	1.4	-1.2	1.4
Exposure to tobacco smoke at home	0.3	0.3	1.1	-0.6	-0.4	-0.4	-0.3	-0.7	1.0	-0.3	-0.3	-0.4	-0.3
Peak expiratory flow (PEF)	0.3	0.7	2.1	-0.3	-1.4	-1.1	-0.4	-0.3	-1.4	-0.8	-0.6	-0.2	1.0
Birth weight	0.3	0.6	4.2	0.4	-0.9	-0.8	0.1	0.4	0.4	0.0	0.1	0.6	2.0
High blood pressure (siblings)	0.3	0.5	1.1	0.8	-0.8	-0.7	0.4	0.7	-1.0	0.3	0.4	-0.8	-0.7
Worry too long after embarrassment	0.3	0.6	2.4	-0.1	-1.5	-1.5	-0.3	-0.2	-0.4	-0.4	-0.1	-0.9	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.7	0.7	-0.6	-0.7	0.6	0.7	-0.3	-0.1	0.6	0.8	-0.8
Medication: Allopurinol	0.3	0.4	1.2	-0.8	0.5	0.7	-0.8	-0.8	-0.2	-0.2	-1.1	0.3	0.5
Mean time to correctly identify matches	0.3	0.6	1.6	0.1	-0.8	-0.7	0.7	0.4	0.2	1.2	0.6	-1.3	-1.1
Friendships satisfaction	0.3	0.4	1.7	0.2	1.3	1.1	0.1	0.1	-0.4	-0.5	0.3	-0.2	-0.5
Osteoarthritis (self-reported)	0.3	0.4	1.2	-0.3	-0.9	-1.1	-0.0	-0.2	-0.1	0.4	0.0	-1.1	0.1
Medication: Gliclazide	0.3	0.4	2.3	0.4	-0.4	-0.3	0.6	0.3	-0.6	-0.1	0.2	-0.4	-1.5
Mother’s age at death	0.3	0.4	1.3	0.0	0.2	0.2	-0.1	-0.0	1.1	0.2	-0.1	1.2	1.1
Irritability	0.3	0.6	2.6	0.9	0.3	0.2	0.5	0.9	-0.2	-0.7	0.4	0.8	-1.6
Age started oral contraceptive pill	0.3	0.4	2.0	0.0	1.4	1.1	0.0	-0.1	0.7	0.3	0.2	0.3	-0.1
Pain experienced in last month	0.3	0.4	1.5	0.4	1.2	1.0	0.5	0.5	-0.7	0.2	0.4	0.7	-0.2
Depressed Affect (Nagel 2018)	0.2	0.5	2.2	0.2	-0.8	-0.7	0.3	0.4	-1.5	-0.9	0.0	0.3	-0.6
Irritable Bowel Disease (IBD)	0.2	0.5	1.8	-0.8	0.1	0.2	-0.4	-0.6	-0.4	-1.1	-0.5	1.4	-0.4
Primary Biliary Cirrhosis	0.2	0.2	0.6	0.3	0.5	0.3	0.4	0.4	0.8	-0.2	0.8	0.0	-0.5
Blood Red Count	0.2	2.4	5.3	1.7	2.3	2.0	1.5	1.6	-0.3	0.6	1.6	1.3	-1.3
Waist Hip Ratio (WHR)	0.2	0.8	1.6	1.1	-0.8	-0.8	1.3	1.2	0.4	0.1	0.8	0.7	-1.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	-0.2	0.2	0.4	-0.1	-0.1	-0.6	-0.9	-0.1	0.6	-0.0
Nervous feelings	0.2	0.4	1.7	-0.1	-0.6	-0.5	-0.2	-0.2	-1.0	-1.3	-0.3	0.5	-0.2
Mouth/teeth dental problems	0.2	0.3	1.9	-0.3	0.4	0.4	-0.1	-0.3	-1.4	-0.1	-0.5	0.4	-0.1
Worrier / anxious feelings	0.2	0.5	0.9	-0.6	-0.5	-0.4	-0.9	-0.8	-0.5	-0.9	-0.9	-0.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.5	-0.3	0.1	0.1	-0.2	-0.3	-0.8	-1.1	-0.2	1.2	0.4
Hair/balding pattern: Pattern 4	0.2	0.5	2.7	-0.4	0.7	0.7	-0.2	-0.2	1.6	-0.8	-0.3	-0.1	-0.1
Headache pain in last month	0.2	0.3	0.9	0.1	0.5	0.2	0.2	-0.1	0.7	-0.7	0.6	1.0	0.4
Illnesses of father: Heart disease	0.2	0.3	0.9	-0.3	0.3	0.3	-0.4	-0.4	0.3	-0.8	-0.5	0.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.9	-0.0	-0.3	-0.3	-0.3	-0.1	-0.1	-0.5	-0.4	1.1	1.4
Mood swings	0.2	0.3	1.5	-0.4	0.0	0.0	-0.3	-0.4	-0.7	-1.2	-0.4	0.6	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.6	0.4	-0.1	0.1	0.4	0.4	-0.5	0.3	-0.1	-0.3	-0.8
Illnesses of father: High blood pressure	0.2	0.2	0.7	0.2	-0.9	-0.8	0.1	0.1	-0.3	-0.6	0.0	0.3	-0.6
Alcohol drinker status: Never	0.2	0.2	1.3	0.1	-0.4	-0.5	0.2	0.0	0.1	-1.1	0.2	0.4	-0.7
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	-0.3	-0.4	-0.1	-0.3	-0.2	0.0	0.2	-0.7	-0.5	-1.0
Reaction Time	0.1	0.2	0.6	-0.2	-0.8	-0.6	0.1	-0.0	-0.4	0.4	0.0	-0.7	-0.5
Blood Eosinophil Count	0.1	0.5	3.0	-0.4	0.9	0.9	-0.2	0.3	0.2	-0.0	-0.0	0.5	1.7
Age when periods started (menarche)	0.1	0.3	1.0	-0.0	0.8	1.0	-0.2	0.2	0.6	-0.6	-0.7	0.5	-0.5
Stomach or abdominal pain in last month	0.1	0.2	0.8	0.0	-0.9	-0.7	-0.0	0.1	-0.6	-0.0	-0.1	0.0	-0.1
Time employed in main current job	0.1	0.2	0.5	-0.4	-0.3	-0.4	0.1	-0.4	0.6	0.7	0.0	-0.5	0.1
Tense / ‘highly strung’	0.1	0.2	1.4	0.1	0.3	0.3	-0.1	0.0	0.2	-1.2	0.1	0.7	-0.0
Average weekly red wine intake	0.1	0.2	1.1	-0.1	-0.5	-0.4	-0.1	-0.1	-1.0	0.4	-0.3	0.3	0.0
Diastolic blood pressure, automated reading	0.1	0.3	0.8	0.3	-0.4	-0.5	0.4	0.3	-0.3	0.9	0.7	-0.9	0.5
Alcohol drinker status: Previous	0.1	0.1	0.6	-0.1	-0.2	-0.2	0.0	-0.2	-0.8	0.1	0.0	-0.4	-0.1
Hair Pigment	0.0	0.8	4.0	-0.6	-0.2	-0.3	0.1	-0.6	2.0	0.4	0.2	-1.2	-1.0
Tanning	0.0	0.4	2.0	0.2	0.5	0.3	0.4	0.2	1.4	0.7	0.8	-0.4	0.1

Hub : Genes

MET

Models

Trait associations