Best TWAS P=2.52e-10 · Best GWAS P=3.02e-13 conditioned to 3.86e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | CEP41 | 0.24 | 0.13 | enet | 20 | 0.13 | 1.5e-04 | 4.4 | 5.7 | 1.2e-08 | -0.04 | 0.16 | 0.08 | TRUE |
| 2 | GTEx | Thyroid | CEP41 | 0.10 | 0.05 | lasso | 7 | 0.06 | 1.7e-05 | 5.0 | 5.5 | 2.9e-08 | -0.01 | 0.48 | 0.03 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | ZC3HC1 | 0.04 | 0.01 | blup | 48 | 0.02 | 8.1e-03 | 6.1 | 6.3 | 2.5e-10 | -0.59 | 0.02 | 0.21 | TRUE |