TWAS
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Cardiovascular Disease
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chr7:129,342,404-130,779,678
Best TWAS P=2.52e-10 · Best GWAS P=3.02e-13 conditioned to 3.86e-05
129.4M
129.6M
129.8M
130M
130.2M
130.4M
130.6M
130.8M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
ZC3HC1
0.04
0.01
blup
48
0.02
8.1e-03
6.1
6.3
2.5e-10
-0.59
0.02
0.21
TRUE
1
GTEx
Brain Cerebellum
CEP41
0.24
0.13
enet
20
0.13
1.5e-04
4.4
5.7
1.2e-08
-0.04
0.16
0.08
TRUE
2
GTEx
Thyroid
CEP41
0.10
0.05
lasso
7
0.06
1.7e-05
5.0
5.5
2.9e-08
-0.01
0.48
0.03
FALSE