[Hub]/) : Traits : Cardiovascular Disease : ← →

chr8:82,017,372-83,452,091

Best TWAS P=7.97e-10 · Best GWAS P=5.93e-10 conditioned to 0.129

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SNX16	0.36	0.45	enet	30	0.49	7.5e-45	5.6	5.5	3.6e-08	0.94	0.03	0.97	FALSE
2	GTEx	Adipose Visceral Omentum	SNX16	0.33	0.29	lasso	7	0.32	1.9e-17	5.6	5.6	1.7e-08	0.91	0.05	0.95	FALSE
3	GTEx	Adrenal Gland	SNX16	0.40	0.17	lasso	12	0.16	1.7e-06	5.6	6.2	8.0e-10	0.90	0.04	0.96	TRUE
4	GTEx	Artery Coronary	SNX16	0.25	0.21	lasso	11	0.22	6.2e-08	6.2	5.2	1.8e-07	0.94	0.01	0.99	FALSE
5	GTEx	Artery Tibial	SNX16	0.36	0.37	lasso	9	0.42	1.8e-35	5.6	5.5	5.1e-08	0.91	0.08	0.92	FALSE
6	GTEx	Brain Cerebellar Hemisphere	SNX16	0.28	0.13	lasso	9	0.24	8.5e-07	6.2	5.1	3.1e-07	0.91	0.02	0.96	FALSE
7	GTEx	Brain Cerebellum	SNX16	0.24	0.05	lasso	13	0.09	1.3e-03	5.6	5.5	3.4e-08	0.86	0.02	0.95	FALSE
8	GTEx	Breast Mammary Tissue	SNX16	0.27	0.38	enet	24	0.40	8.8e-22	5.6	5.5	3.3e-08	0.90	0.06	0.94	FALSE
9	GTEx	Breast Mammary Tissue (Male)	SNX16	0.16	0.11	lasso	8	0.08	6.9e-03	5.7	5.7	1.2e-08	0.89	0.03	0.69	FALSE
10	GTEx	Cells Transformed fibroblasts	SNX16	0.29	0.38	enet	26	0.40	1.2e-31	6.1	5.7	1.0e-08	0.96	0.02	0.98	FALSE
11	GTEx	Colon Sigmoid	SNX16	0.39	0.31	lasso	11	0.33	3.0e-12	5.6	5.2	1.6e-07	0.92	0.03	0.97	FALSE
12	GTEx	Colon Transverse	SNX16	0.28	0.36	lasso	5	0.38	5.5e-19	5.6	5.9	3.1e-09	0.85	0.05	0.95	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	SNX16	0.37	0.39	lasso	8	0.39	2.6e-15	5.6	5.8	5.4e-09	0.91	0.04	0.96	FALSE
14	GTEx	Esophagus Mucosa	SNX16	0.13	0.18	enet	19	0.17	1.6e-11	5.6	5.2	2.6e-07	0.89	0.07	0.93	FALSE
15	GTEx	Esophagus Muscularis	SNX16	0.36	0.34	enet	35	0.37	1.0e-23	5.6	5.3	1.2e-07	0.90	0.04	0.96	FALSE
16	GTEx	Lung	SNX16	0.40	0.41	lasso	7	0.46	1.8e-38	5.6	5.9	2.8e-09	0.96	0.02	0.98	FALSE
17	GTEx	Nerve Tibial	SNX16	0.29	0.29	lasso	4	0.32	2.6e-23	6.1	5.7	1.0e-08	0.96	0.02	0.98	FALSE
18	GTEx	Pancreas	SNX16	0.20	0.17	enet	22	0.16	4.4e-07	5.6	5.2	1.9e-07	0.88	0.03	0.97	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	SNX16	0.36	0.31	lasso	11	0.32	8.2e-18	6.1	5.6	1.8e-08	0.98	0.01	0.99	FALSE
20	GTEx	Skin Sun Exposed Lower leg	SNX16	0.27	0.32	lasso	7	0.31	8.4e-26	5.7	5.8	8.7e-09	0.91	0.06	0.94	FALSE
21	GTEx	Spleen	SNX16	0.30	0.20	lasso	8	0.14	2.4e-04	5.6	5.1	3.0e-07	0.87	0.04	0.88	FALSE
22	GTEx	Stomach	SNX16	0.26	0.16	lasso	10	0.18	4.5e-09	5.6	5.9	4.3e-09	0.90	0.04	0.96	FALSE
23	GTEx	Testis	SNX16	0.53	0.62	lasso	6	0.63	6.1e-35	5.6	5.8	7.9e-09	0.91	0.06	0.94	FALSE
24	GTEx	Thyroid	SNX16	0.23	0.26	lasso	6	0.27	1.1e-20	5.7	5.6	2.6e-08	0.89	0.06	0.94	FALSE
25	GTEx	Vagina	SNX16	0.25	0.23	lasso	3	0.21	1.3e-05	5.6	5.6	2.1e-08	0.82	0.04	0.74	FALSE
26	GTEx	Whole Blood	SNX16	0.09	0.03	enet	14	0.04	1.7e-04	5.9	5.3	1.1e-07	0.84	0.04	0.96	FALSE
27	METSIM	Adipose	SNX16	0.21	0.32	bslmm	335	0.32	9.9e-49	5.9	5.7	1.4e-08	0.90	0.06	0.94	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNX16	0.10	0.17	lasso	7	0.18	1.1e-35	5.7	5.2	1.9e-07	0.89	0.02	0.98	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	SNX16	0.13	0.14	lasso	11	0.14	1.2e-08	5.9	5.6	1.7e-08	0.91	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	SNX16	0.21	0.34	lasso	11	0.35	7.6e-38	5.6	5.6	2.4e-08	0.91	0.01	0.99	FALSE