TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Cardiovascular Disease
:
←
→
chr8:19,064,892-20,521,138
Best TWAS P=2.29e-08 · Best GWAS P=1.04e-08 conditioned to 0.046
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
20.4M
20.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
LPL
0.06
0.07
lasso
2
0.06
6.5e-20
-5.6
-5.6
2.3e-08
0.82
0.01
0.99
TRUE
1
NTR
Blood
LPL
0.08
0.05
bslmm
667
0.06
5.5e-20
-5.7
-5.4
5.3e-08
0.92
0.01
0.99
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
LPL
0.03
0.00
blup
88
0.00
1.3e-01
-3.0
-5.4
5.7e-08
0.59
0.06
0.26
FALSE