Best TWAS P=2.29e-08 · Best GWAS P=1.04e-08 conditioned to 0.046
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | LPL | 0.08 | 0.05 | bslmm | 667 | 0.06 | 5.5e-20 | -5.7 | -5.4 | 5.3e-08 | 0.92 | 0.01 | 0.99 | FALSE |
2 | YFS | Blood | LPL | 0.06 | 0.07 | lasso | 2 | 0.06 | 6.5e-20 | -5.6 | -5.6 | 2.3e-08 | 0.82 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LPL | 0.03 | 0.00 | blup | 88 | 0.00 | 1.3e-01 | -3.0 | -5.4 | 5.7e-08 | 0.59 | 0.06 | 0.26 | FALSE |