[Hub]/) : Traits : Cardiovascular Disease :

chr8:95,199,215-96,825,195

Best TWAS P=2.34e-10 · Best GWAS P=6.93e-09 conditioned to 0.328

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CCNE2 0.16 0.08 enet 20 0.06 5.8e-04 5.8 -5.2 2.3e-07 -0.89 0.01 0.99 FALSE
2 GTEx Artery Aorta TP53INP1 0.08 0.02 enet 18 0.03 9.7e-03 -5.1 5.2 2.1e-07 0.61 0.09 0.76 FALSE
3 GTEx Brain Cerebellum NDUFAF6 0.28 0.13 lasso 7 0.14 5.8e-05 5.8 -5.7 1.6e-08 -0.95 0.01 0.99 FALSE
4 GTEx Cells Transformed fibroblasts NDUFAF6 0.07 0.03 enet 9 0.01 7.6e-02 5.8 -6.3 2.3e-10 -0.83 0.01 0.97 TRUE
5 GTEx Heart Atrial Appendage NDUFAF6 0.17 0.03 lasso 6 0.04 6.7e-03 -4.6 -5.7 1.5e-08 -0.77 0.05 0.75 FALSE
6 GTEx Heart Left Ventricle NDUFAF6 0.10 0.05 lasso 11 0.07 1.6e-04 4.6 -5.2 1.5e-07 -0.50 0.09 0.87 FALSE
7 GTEx Whole Blood TP53INP1 0.07 0.04 enet 13 0.02 2.9e-03 5.8 5.6 2.1e-08 0.90 0.01 0.99 FALSE
8 YFS Blood TP53INP1 0.03 0.02 lasso 5 0.02 8.0e-07 3.8 5.7 1.2e-08 0.82 0.04 0.96 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TP53INP1 0.04 0.05 blup 56 0.06 4.2e-07 5.8 5.9 4.1e-09 0.95 0.01 0.99 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma TP53INP1 0.06 0.02 lasso 3 0.03 2.8e-03 5.8 5.8 8.0e-09 0.96 0.01 0.97 FALSE