TWAS
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Traits
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Cardiovascular Disease
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chr8:102,002,608-103,832,256
Best TWAS P=1.78e-10 · Best GWAS P=1.84e-09 conditioned to 0.0299
102M
102.5M
103M
103.5M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
KB-1107E3.1
0.26
0.08
enet
31
0.10
2.8e-05
-5.7
6.4
1.8e-10
-0.70
0.03
0.95
TRUE
1
GTEx
Testis
NCALD
0.24
0.20
lasso
5
0.19
9.2e-09
-5.7
5.8
7.5e-09
-0.91
0.04
0.95
FALSE