TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Cardiovascular Disease
:
←
→
chr9:35,208,145-36,597,142
Best TWAS P=5.9e-08 · Best GWAS P=3.77e-07 conditioned to 0.0641
35.2M
35.4M
35.6M
35.8M
36M
36.2M
36.4M
36.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
HRCT1
0.11
0.02
enet
22
0.05
4.4e-04
4.8
5.4
5.9e-08
0.69
0.01
0.81
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HRCT1
0.14
0.01
blup
49
0.09
2.7e-10
-3.1
5.2
2.2e-07
0.61
0.21
0.46
FALSE