Best TWAS P=5.9e-08 · Best GWAS P=3.77e-07 conditioned to 0.0641
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | HRCT1 | 0.11 | 0.02 | enet | 22 | 0.05 | 4.4e-04 | 4.8 | 5.4 | 5.9e-08 | 0.69 | 0.01 | 0.81 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HRCT1 | 0.14 | 0.01 | blup | 49 | 0.09 | 2.7e-10 | -3.1 | 5.2 | 2.2e-07 | 0.61 | 0.21 | 0.46 | FALSE |