Best TWAS P=2.52e-09 · Best GWAS P=1.39e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RP11-513M16.8 | 0.23 | 0.14 | lasso | 4 | 0.13 | 1.1e-09 | 5.6 | 5.5 | 3.8e-08 | 0.99 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Colon Transverse | RPS6 | 0.13 | 0.04 | lasso | 2 | 0.01 | 8.6e-02 | 5.4 | -5.1 | 2.8e-07 | -0.86 | 0.03 | 0.86 | FALSE |
| 3 | GTEx | Stomach | RP11-513M16.7 | 0.20 | 0.10 | lasso | 4 | 0.09 | 6.2e-05 | 4.8 | 5.1 | 2.7e-07 | 0.94 | 0.04 | 0.95 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | RPS6 | 0.11 | 0.08 | lasso | 5 | 0.07 | 8.0e-10 | 5.7 | -6.0 | 2.5e-09 | -0.98 | 0.00 | 1.00 | TRUE |