Best TWAS P=1.94e-10 · Best GWAS P=1.28e-15 conditioned to 0.00951
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NOC3L | 0.10 | 0.11 | lasso | 5 | 0.12 | 4.7e-14 | -4.3 | -5.3 | 1.2e-07 | -0.53 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adrenal Gland | NOC3L | 0.21 | 0.10 | lasso | 5 | 0.18 | 4.4e-07 | -1.4 | -5.5 | 4.0e-08 | -0.52 | 0.82 | 0.04 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | NOC3L | 0.40 | 0.03 | enet | 34 | 0.12 | 8.9e-04 | -5.8 | -5.3 | 8.9e-08 | -0.36 | 0.04 | 0.20 | FALSE |
| 4 | GTEx | Muscle Skeletal | NOC3L | 0.09 | 0.05 | enet | 7 | 0.05 | 7.5e-06 | -4.3 | -6.4 | 1.9e-10 | -0.54 | 0.84 | 0.04 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NOC3L | 0.05 | 0.01 | enet | 5 | 0.03 | 6.3e-04 | 6.4 | -5.8 | 9.0e-09 | -0.76 | 0.01 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NOC3L | 0.08 | 0.06 | lasso | 2 | 0.04 | 5.8e-03 | -5.8 | -5.7 | 1.0e-08 | -0.51 | 0.03 | 0.41 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | HELLS | 0.05 | 0.02 | blup | 47 | 0.03 | 9.6e-04 | -3.3 | -5.3 | 8.9e-08 | -0.54 | 0.09 | 0.77 | TRUE |