TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Cardiovascular Disease
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chr11:9,003,306-10,471,931
Best TWAS P=2.68e-16 · Best GWAS P=1.61e-19 conditioned to 4.69e-06
9M
9.2M
9.4M
9.6M
9.8M
10M
10.2M
10.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
SWAP70
0.09
0.07
bslmm
379
0.08
1.6e-24
-8.9
-8.2
2.7e-16
0.71
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
SWAP70
0.17
0.02
blup
77
0.06
1.9e-03
-8.7
-7.2
8.0e-13
0.81
0.01
0.79
FALSE
2
GTEx
Skin Sun Exposed Lower leg
SWAP70
0.17
0.05
lasso
6
0.10
1.3e-08
-8.9
-6.9
5.3e-12
0.61
0.01
0.99
FALSE
1
GTEx
Nerve Tibial
SWAP70
0.18
0.04
enet
19
0.12
5.0e-09
-2.8
-5.3
1.1e-07
0.29
0.52
0.26
FALSE