Best TWAS P=2.68e-16 · Best GWAS P=1.61e-19 conditioned to 4.69e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | SWAP70 | 0.18 | 0.04 | enet | 19 | 0.12 | 5.0e-09 | -2.8 | -5.3 | 1.1e-07 | 0.29 | 0.52 | 0.26 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | SWAP70 | 0.17 | 0.05 | lasso | 6 | 0.10 | 1.3e-08 | -8.9 | -6.9 | 5.3e-12 | 0.61 | 0.01 | 0.99 | FALSE |
3 | YFS | Blood | SWAP70 | 0.09 | 0.07 | bslmm | 379 | 0.08 | 1.6e-24 | -8.9 | -8.2 | 2.7e-16 | 0.71 | 0.00 | 1.00 | TRUE |
4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SWAP70 | 0.17 | 0.02 | blup | 77 | 0.06 | 1.9e-03 | -8.7 | -7.2 | 8.0e-13 | 0.81 | 0.01 | 0.79 | FALSE |