[Hub]/) : Traits : Cardiovascular Disease : ← →

chr11:1,213,806-2,705,175

Best TWAS P=2.05e-20 · Best GWAS P=1.09e-22 conditioned to 0.0286

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LSP1	0.07	0.03	lasso	4	0.03	2.4e-04	8.1	-9.3	2.1e-20	0.63	0.11	0.08	TRUE
4	GTEx	Cells Transformed fibroblasts	LSP1	0.21	0.04	enet	28	0.06	3.4e-05	9.5	7.6	2.6e-14	-0.45	0.04	0.94	TRUE
1	GTEx	Artery Aorta	TNNT3	0.21	-0.01	enet	17	0.00	6.4e-01	-1.7	-5.6	2.6e-08	0.16	0.05	0.06	TRUE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LSP1	0.12	0.08	lasso	5	0.10	5.0e-11	-8.1	-9.1	1.1e-19	0.87	0.00	1.00	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	TNNT3	0.33	0.16	lasso	7	0.17	2.0e-09	7.8	8.3	8.8e-17	-0.45	0.07	0.93	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNNI2	0.11	0.09	lasso	2	0.08	4.1e-06	8.1	-8.1	5.6e-16	0.48	0.34	0.48	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LSP1	0.06	0.04	enet	6	0.04	3.1e-05	8.1	7.5	5.8e-14	-0.50	0.36	0.48	FALSE
11	YFS	Blood	TNNT3	0.02	0.02	lasso	3	0.01	1.9e-05	7.8	-6.9	5.3e-12	0.42	0.24	0.71	FALSE
3	GTEx	Brain Frontal Cortex BA9	MRPL23-AS1	0.36	0.23	lasso	3	0.21	3.8e-06	6.6	6.6	5.4e-11	-0.33	0.42	0.13	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	MRPL23-AS1	0.33	0.19	enet	30	0.21	9.5e-12	5.8	6.5	8.7e-11	-0.25	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC100133545	0.03	0.01	blup	49	0.01	1.1e-02	5.8	5.9	2.9e-09	-0.30	0.00	0.93	FALSE
10	GTEx	Skin Sun Exposed Lower leg	MRPL23-AS1	0.19	0.19	enet	9	0.21	5.3e-17	4.7	5.8	8.1e-09	-0.30	1.00	0.00	FALSE
2	GTEx	Artery Aorta	MRPL23-AS1	0.22	0.07	enet	10	0.12	2.9e-07	6.6	5.6	1.7e-08	-0.29	0.97	0.00	FALSE
6	GTEx	Nerve Tibial	MRPL23-AS1	0.18	0.11	lasso	4	0.16	1.2e-11	5.8	5.4	7.3e-08	-0.28	1.00	0.00	FALSE
9	GTEx	Skin Sun Exposed Lower leg	TNNT3	0.63	0.02	lasso	20	0.00	3.5e-01	-5.3	5.2	2.3e-07	-0.50	0.02	0.64	FALSE
5	GTEx	Colon Sigmoid	MRPL23-AS1	0.39	0.13	lasso	6	0.23	9.8e-09	4.7	5.1	2.9e-07	-0.31	0.92	0.01	FALSE