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chr11:106,485,489-108,027,561

Best TWAS P=8.89e-13 · Best GWAS P=4.07e-14 conditioned to 0.00206

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Muscle Skeletal	CWF19L2	0.08	0.05	lasso	3	0.05	1.1e-05	6.8	7.2	8.9e-13	0.80	0.04	0.96	TRUE
11	GTEx	Testis	CWF19L2	0.20	0.09	lasso	6	0.09	1.0e-04	6.8	7.1	1.1e-12	0.72	0.34	0.46	FALSE
5	GTEx	Breast Mammary Tissue (Male)	RP11-819C21.1	0.15	-0.01	lasso	1	-0.01	7.0e-01	6.8	-6.8	8.8e-12	-0.80	0.04	0.19	FALSE
7	GTEx	Heart Left Ventricle	CWF19L2	0.10	0.07	lasso	4	0.05	1.4e-03	5.7	6.5	6.3e-11	0.69	0.46	0.29	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	RP11-819C21.1	0.27	0.10	lasso	5	0.19	9.4e-11	-4.0	-6.4	1.9e-10	-0.81	0.01	0.99	FALSE
2	GTEx	Brain Cerebellum	RP11-819C21.1	0.18	0.08	enet	2	0.02	8.8e-02	6.8	-6.2	6.9e-10	-0.76	0.06	0.48	FALSE
6	GTEx	Cells Transformed fibroblasts	RP11-819C21.1	0.11	0.06	lasso	8	0.05	2.1e-04	5.8	-5.9	3.5e-09	-0.60	0.82	0.10	FALSE
4	GTEx	Breast Mammary Tissue	RP11-819C21.1	0.14	0.09	enet	12	0.09	2.6e-05	6.8	-5.9	4.0e-09	-0.67	0.15	0.80	FALSE
3	GTEx	Brain Nucleus accumbens basal ganglia	RP11-819C21.1	0.39	0.17	enet	26	0.23	1.0e-06	-3.6	-5.7	1.0e-08	-0.61	0.14	0.79	FALSE
13	GTEx	Whole Blood	RP11-819C21.1	0.06	0.03	lasso	2	0.01	4.8e-02	5.5	-5.6	2.3e-08	-0.53	0.15	0.30	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CWF19L2	0.05	0.00	blup	106	0.01	3.4e-02	2.3	5.6	2.3e-08	0.71	0.03	0.05	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	CWF19L2	0.11	0.01	blup	105	0.02	3.0e-02	-2.6	5.5	2.9e-08	0.62	0.06	0.09	FALSE
9	GTEx	Ovary	RP11-819C21.1	0.31	0.11	enet	28	0.22	3.9e-06	5.5	-5.5	3.8e-08	-0.69	0.05	0.86	FALSE
14	METSIM	Adipose	CWF19L2	0.08	0.03	blup	517	0.05	6.5e-08	6.8	5.4	6.3e-08	0.62	0.26	0.74	FALSE
12	GTEx	Thyroid	RP11-819C21.1	0.14	0.11	enet	21	0.13	3.0e-10	-4.0	-5.2	1.6e-07	-0.62	0.46	0.54	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CWF19L2	0.13	0.01	enet	9	0.04	1.4e-02	-3.5	5.2	2.6e-07	0.65	0.03	0.34	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CWF19L2	0.08	0.00	blup	106	0.03	3.0e-04	-4.2	5.1	2.8e-07	0.66	0.39	0.09	FALSE
1	GTEx	Brain Cerebellar Hemisphere	RP11-819C21.1	0.37	0.16	enet	23	0.24	8.8e-07	-2.3	-5.1	2.9e-07	-0.47	0.37	0.18	FALSE