Best TWAS P=2.92e-41 · Best GWAS P=1.02e-40 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -13.4 | -13.5 | 2.9e-41 | 0.98 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -13.4 | -13.2 | 9.3e-40 | 0.94 | 0.00 | 1.00 | FALSE |
| 1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -12.9 | -11.3 | 1.8e-29 | 0.86 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | TMEM133 | 0.30 | 0.15 | enet | 34 | 0.19 | 7.1e-11 | -13.4 | -10.6 | 4.2e-26 | 0.72 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ARHGAP42 | 0.04 | 0.01 | blup | 266 | 0.02 | 1.1e-04 | 4.8 | -7.6 | 3.4e-14 | 0.57 | 0.04 | 0.88 | FALSE |
| 5 | GTEx | Cells Transformed fibroblasts | ARHGAP42 | 0.15 | 0.10 | enet | 20 | 0.08 | 2.6e-06 | 6.5 | -6.6 | 4.9e-11 | 0.46 | 0.71 | 0.23 | FALSE |