Best TWAS P=3.58e-09 · Best GWAS P=1.91e-34 conditioned to 2.08e-33
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | HADH | 0.06 | 0.02 | bslmm | 380 | 0.03 | 8.1e-05 | 4.4 | 5.9 | 3.6e-09 | 0.03 | 0.97 | 0.0 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HADH | 0.05 | 0.01 | blup | 55 | 0.02 | 1.7e-03 | 5.9 | 5.8 | 8.7e-09 | 0.03 | 0.02 | 0.6 | FALSE |