[Hub]/) : Traits : Height :

chr4:105,373,669-107,092,169

Best TWAS P=6.95e-65 · Best GWAS P=1.53e-85 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPA2 0.08 0.03 bslmm 429 0.04 2.2e-05 -12.25 -14.0 1.1e-44 -0.55 0.18 0.74 TRUE
2 GTEx Adipose Subcutaneous PPA2 0.15 0.02 enet 36 0.06 7.0e-06 10.69 -8.0 1.3e-15 -0.44 0.23 0.24 TRUE
3 GTEx Adipose Visceral Omentum PPA2 0.15 0.04 lasso 6 0.05 9.1e-04 9.60 -6.0 2.6e-09 -0.38 0.14 0.09 FALSE
4 GTEx Artery Aorta PPA2 0.11 -0.01 enet 24 0.01 1.6e-01 -17.55 -11.1 1.3e-28 -0.49 0.06 0.40 FALSE
5 GTEx Artery Tibial PPA2 0.08 0.02 enet 19 0.04 5.0e-04 -12.65 -5.3 1.4e-07 -0.38 0.18 0.16 FALSE
6 GTEx Brain Cerebellum PPA2 0.22 0.01 lasso 4 0.03 3.7e-02 -12.65 -10.0 1.5e-23 -0.44 0.09 0.10 FALSE
7 GTEx Brain Cortex PPA2 0.14 0.09 lasso 9 0.09 1.6e-03 -14.03 -14.2 4.7e-46 -0.54 0.04 0.73 TRUE
8 GTEx Breast Mammary Tissue PPA2 0.26 0.06 lasso 5 0.04 2.7e-03 0.59 -5.5 3.6e-08 -0.28 0.14 0.20 FALSE
9 GTEx Breast Mammary Tissue (Female) PPA2 0.15 0.02 lasso 4 0.00 2.8e-01 -8.02 -5.2 2.5e-07 -0.23 0.05 0.12 TRUE
10 GTEx Cells Transformed fibroblasts PPA2 0.11 0.03 lasso 3 0.01 6.5e-02 -9.92 -11.4 6.5e-30 -0.39 0.40 0.15 FALSE
11 GTEx Esophagus Gastroesophageal Junction PPA2 0.29 0.15 lasso 5 0.14 8.8e-06 -17.55 -17.0 7.0e-65 -0.64 0.03 0.95 TRUE
12 GTEx Esophagus Mucosa PPA2 0.18 0.06 enet 14 0.12 2.5e-08 18.02 -17.0 1.9e-64 -0.76 0.07 0.93 TRUE
13 GTEx Heart Atrial Appendage PPA2 0.15 0.05 lasso 7 0.06 7.4e-04 -14.76 -8.5 2.6e-17 -0.29 0.22 0.43 TRUE
14 GTEx Lung PPA2 0.09 0.02 enet 16 0.03 1.4e-03 2.83 -8.4 3.8e-17 -0.46 0.20 0.31 FALSE
15 GTEx Muscle Skeletal PPA2 0.19 0.06 enet 28 0.11 8.7e-11 -13.76 -10.5 1.1e-25 -0.41 0.93 0.06 FALSE
16 GTEx Nerve Tibial PPA2 0.13 0.07 enet 23 0.07 2.1e-05 -12.65 -12.3 5.1e-35 -0.45 0.38 0.42 FALSE
17 GTEx Ovary PPA2 0.18 0.10 lasso 3 0.14 2.2e-04 -12.65 -15.1 2.3e-51 -0.58 0.05 0.73 TRUE
18 GTEx Skin Sun Exposed Lower leg PPA2 0.09 0.07 lasso 3 0.04 4.3e-04 9.60 -9.7 3.4e-22 -0.46 0.65 0.05 FALSE
19 GTEx Skin Sun Exposed Lower leg TET2 0.09 0.01 enet 18 0.02 3.6e-03 -18.14 -12.1 9.5e-34 -0.49 0.01 0.94 TRUE
20 GTEx Thyroid PPA2 0.22 0.01 enet 18 0.12 2.9e-09 10.57 -9.1 1.1e-19 -0.53 0.74 0.07 FALSE
21 METSIM Adipose PPA2 0.08 0.05 lasso 2 0.04 3.7e-07 9.60 10.1 5.7e-24 0.46 0.96 0.01 TRUE
22 ROSMAP Brain Pre-frontal Cortex PPA2 0.32 0.38 lasso 2 0.38 1.1e-51 9.60 -10.5 6.0e-26 -0.48 1.00 0.00 FALSE
23 YFS Blood PPA2 0.22 0.05 lasso 19 0.12 9.7e-38 -6.23 8.8 9.3e-19 0.33 1.00 0.00 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma ARHGEF38 0.02 0.01 blup 82 0.01 2.0e-03 -3.18 -7.7 1.5e-14 -0.17 0.01 0.06 TRUE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPA2 0.11 0.03 blup 84 0.03 4.7e-04 -12.65 -8.0 1.5e-15 -0.34 0.18 0.68 TRUE
26 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPA2 0.29 0.01 blup 84 0.10 4.3e-06 -8.02 -6.0 1.9e-09 -0.31 0.13 0.12 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma PPA2 0.11 0.02 blup 84 0.02 1.5e-03 -8.02 -6.3 3.9e-10 -0.30 0.48 0.04 TRUE
28 The Cancer Genome Atlas Thyroid Carcinoma PPA2 0.04 0.02 blup 84 0.04 6.1e-05 -13.76 -12.2 5.0e-34 -0.44 0.14 0.65 FALSE