Best TWAS P=1.86e-24 · Best GWAS P=9.55e-39 conditioned to 7.41e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | DAB2 | 0.20 | 0.20 | lasso | 14 | 0.21 | 3.0e-67 | 9.1 | -9.5 | 1.8e-21 | 0.58 | 1.00 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DAB2 | 0.04 | 0.01 | enet | 9 | 0.02 | 3.3e-03 | -12.6 | -10.2 | 1.9e-24 | 0.74 | 0.02 | 0.66 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C9 | 0.04 | 0.00 | blup | 89 | 0.03 | 2.8e-04 | -4.9 | -7.2 | 4.5e-13 | 0.58 | 0.02 | 0.06 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DAB2 | 0.07 | 0.00 | enet | 6 | 0.02 | 2.1e-03 | 2.8 | -7.5 | 6.7e-14 | 0.58 | 0.01 | 0.71 | FALSE |
| 5 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | DAB2 | 0.18 | -0.01 | blup | 83 | 0.05 | 2.0e-02 | 1.2 | -9.2 | 2.5e-20 | 0.48 | 0.02 | 0.14 | FALSE |