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chr5:41,032,998-44,296,986

Best TWAS P=1.14e-31 · Best GWAS P=1.16e-49 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C5orf51	0.03	0.03	lasso	1	0.03	3.0e-04	-6.8	6.8	9.7e-12	-0.22	0.56	0.38	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CCDC152	0.18	0.08	lasso	7	0.07	4.3e-09	5.3	7.3	3.3e-13	-0.27	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	GHR	0.25	0.07	bslmm	382	0.13	2.6e-15	-11.1	11.0	3.0e-28	-0.60	0.02	0.98	FALSE
4	CommonMind	Brain Pre-frontal Cortex	SEPP1	0.06	0.00	blup	330	0.04	1.9e-05	1.7	-7.6	2.9e-14	0.38	0.32	0.22	FALSE
5	CommonMind	Brain Pre-frontal Cortex	ZNF131	0.07	0.02	blup	349	0.02	5.7e-04	1.7	7.9	3.9e-15	-0.53	0.17	0.64	FALSE
6	GTEx	Adipose Subcutaneous	ZNF131	0.09	0.06	lasso	11	0.04	2.1e-04	-5.1	6.7	1.6e-11	-0.18	0.87	0.01	FALSE
7	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	11.0	10.9	1.3e-27	-0.54	0.84	0.05	FALSE
8	GTEx	Adipose Visceral Omentum	ZNF131	0.12	0.02	enet	39	0.04	3.4e-03	4.4	5.9	4.3e-09	-0.45	0.06	0.28	FALSE
9	GTEx	Adipose Visceral Omentum	CCDC152	0.09	0.06	lasso	9	0.05	1.9e-03	10.7	10.4	3.2e-25	-0.57	0.16	0.14	TRUE
10	GTEx	Artery Aorta	CCDC152	0.31	0.24	lasso	8	0.24	2.5e-13	10.7	8.8	1.7e-18	-0.42	1.00	0.00	FALSE
11	GTEx	Artery Coronary	CCDC152	0.20	0.13	lasso	2	0.12	7.7e-05	10.7	10.8	5.4e-27	-0.56	0.63	0.11	FALSE
12	GTEx	Artery Tibial	ZNF131	0.08	0.07	lasso	11	0.06	1.2e-05	-5.3	5.8	6.3e-09	-0.20	0.90	0.00	FALSE
13	GTEx	Artery Tibial	CTD-2201E18.3	0.10	0.05	lasso	4	0.06	1.9e-05	-4.6	5.9	3.9e-09	-0.28	0.92	0.00	FALSE
14	GTEx	Artery Tibial	CCDC152	0.22	0.17	enet	35	0.18	1.8e-14	10.7	9.0	2.4e-19	-0.44	1.00	0.00	FALSE
15	GTEx	Brain Frontal Cortex BA9	ZNF131	0.25	0.17	lasso	10	0.15	8.3e-05	-5.5	5.5	3.0e-08	-0.18	0.14	0.08	FALSE
16	GTEx	Breast Mammary Tissue	CTD-2201E18.3	0.10	0.06	lasso	1	0.02	4.3e-02	5.3	5.3	1.1e-07	-0.28	0.23	0.05	FALSE
17	GTEx	Cells Transformed fibroblasts	CTD-2201E18.5	0.06	0.03	enet	10	0.03	1.2e-03	-7.0	-8.2	3.5e-16	0.38	0.55	0.14	TRUE
18	GTEx	Esophagus Mucosa	FBXO4	0.08	0.06	lasso	3	0.04	8.0e-04	-6.8	6.8	1.5e-11	-0.23	0.32	0.03	FALSE
19	GTEx	Esophagus Mucosa	ZNF131	0.09	0.06	enet	8	0.06	1.5e-04	-5.9	7.5	4.5e-14	-0.11	0.44	0.03	TRUE
20	GTEx	Esophagus Mucosa	SEPP1	0.07	0.04	enet	15	0.05	4.7e-04	2.0	5.7	9.2e-09	-0.40	0.15	0.22	FALSE
21	GTEx	Esophagus Muscularis	ZNF131	0.16	0.06	lasso	12	0.10	6.4e-07	-5.4	6.0	1.7e-09	-0.21	1.00	0.00	FALSE
22	GTEx	Esophagus Muscularis	CCDC152	0.13	0.09	lasso	8	0.10	7.9e-07	9.5	8.6	1.0e-17	-0.43	0.96	0.00	FALSE
23	GTEx	Lung	NNT-AS1	0.07	0.02	lasso	11	0.02	2.3e-02	-4.9	-5.2	1.8e-07	0.11	0.18	0.46	TRUE
24	GTEx	Muscle Skeletal	OXCT1	0.06	0.06	lasso	3	0.04	4.3e-05	-6.5	-6.6	3.6e-11	0.22	0.74	0.13	FALSE
25	GTEx	Muscle Skeletal	OXCT1-AS1	0.10	0.02	enet	25	0.08	2.9e-08	-6.5	-5.7	8.9e-09	0.09	0.80	0.07	FALSE
26	GTEx	Nerve Tibial	CCDC152	0.16	0.06	enet	25	0.06	2.9e-05	10.7	6.4	1.9e-10	-0.29	0.93	0.00	FALSE
27	GTEx	Skin Sun Exposed Lower leg	NIM1	0.09	0.01	lasso	12	0.03	2.2e-03	-6.7	-5.9	4.8e-09	0.16	0.44	0.02	FALSE
28	GTEx	Spleen	NNT-AS1	0.40	0.01	enet	31	0.23	1.2e-06	-4.9	-6.1	9.4e-10	0.11	0.05	0.65	FALSE
29	GTEx	Stomach	SERBP1P6	0.12	0.03	enet	16	0.01	6.7e-02	-7.7	10.9	7.3e-28	-0.38	0.08	0.15	FALSE
30	GTEx	Thyroid	CCDC152	0.10	0.07	lasso	4	0.04	4.2e-04	10.7	10.8	2.7e-27	-0.56	0.75	0.10	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	CCDC152	0.20	0.09	lasso	10	0.09	5.2e-12	5.3	9.5	2.7e-21	-0.34	1.00	0.00	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	C5orf51	0.03	0.01	bslmm	298	0.02	1.9e-03	-6.8	6.9	6.2e-12	-0.14	0.30	0.05	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	SEPP1	0.18	0.19	lasso	11	0.21	1.3e-26	9.8	-10.6	2.5e-26	0.55	1.00	0.00	FALSE
34	YFS	Blood	CCDC152	0.07	0.06	enet	16	0.06	2.0e-19	11.0	11.6	6.8e-31	-0.60	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	OXCT1	0.04	0.03	blup	58	0.03	1.8e-03	-6.8	-7.0	2.5e-12	0.23	0.02	0.87	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	C5orf39	0.02	0.01	blup	26	0.01	6.2e-03	4.9	-5.2	1.7e-07	0.30	0.01	0.56	FALSE
37	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEPP1	0.01	0.00	enet	7	0.01	1.5e-03	10.4	-8.8	1.7e-18	0.63	0.04	0.12	TRUE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC152	0.06	0.06	blup	40	0.07	1.6e-08	9.4	-11.7	1.1e-31	0.71	0.76	0.24	TRUE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OXCT1	0.04	0.05	blup	58	0.05	9.4e-07	-5.7	-6.0	1.5e-09	0.07	0.93	0.03	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF131	0.04	0.04	lasso	1	0.03	2.2e-04	-5.4	5.4	8.3e-08	-0.19	0.03	0.94	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	C5orf51	0.02	0.01	lasso	3	0.01	5.9e-02	-6.5	6.5	6.0e-11	-0.22	0.01	0.77	FALSE
42	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C5orf51	0.25	0.00	lasso	7	0.00	4.3e-01	-6.3	-7.0	2.3e-12	0.19	0.01	0.32	TRUE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC152	0.15	0.12	lasso	6	0.12	1.0e-12	10.4	-10.6	4.1e-26	0.56	1.00	0.00	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	GHR	0.12	0.11	enet	6	0.13	2.5e-13	-8.6	-9.7	2.6e-22	-0.04	1.00	0.00	TRUE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEPP1	0.06	0.02	blup	38	0.04	5.2e-05	9.5	-11.3	7.8e-30	0.74	0.22	0.70	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF131	0.05	0.03	enet	7	0.04	5.3e-05	-5.9	5.4	6.0e-08	-0.12	0.00	0.98	FALSE