Best TWAS P=6.95e-25 · Best GWAS P=2.63e-79 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100272217 | 0.24 | 0.23 | enet | 16 | 0.24 | 1.7e-28 | 5.8 | 5.3 | 8.7e-08 | -0.16 | 1.00 | 0.00 | FALSE |
| 2 | YFS | Blood | EXOSC2 | 0.05 | 0.05 | lasso | 2 | 0.05 | 2.0e-15 | 5.4 | -5.5 | 4.4e-08 | 0.25 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | LOC100272217 | 0.10 | 0.04 | lasso | 8 | 0.07 | 1.8e-06 | 10.3 | 8.0 | 1.1e-15 | -0.13 | 0.44 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LOC100272217 | 0.09 | 0.04 | enet | 11 | 0.06 | 1.6e-11 | 5.8 | 8.4 | 4.1e-17 | -0.18 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | LOC100272217 | 0.09 | 0.04 | lasso | 3 | 0.07 | 1.1e-04 | 10.3 | 9.6 | 9.9e-22 | -0.30 | 0.07 | 0.06 | FALSE |
| 6 | The Cancer Genome Atlas | Esophageal Carcinoma | LOC100272217 | 0.28 | 0.12 | lasso | 4 | 0.09 | 9.3e-04 | 5.8 | 6.4 | 1.4e-10 | -0.20 | 0.08 | 0.06 | FALSE |
| 7 | The Cancer Genome Atlas | Glioblastoma Multiforme | LOC100272217 | 0.29 | 0.14 | blup | 43 | 0.17 | 6.7e-06 | 5.8 | 10.3 | 6.9e-25 | -0.29 | 0.36 | 0.05 | TRUE |
| 8 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LOC100272217 | 0.10 | 0.09 | enet | 9 | 0.09 | 3.3e-10 | 5.8 | 6.7 | 1.6e-11 | -0.17 | 1.00 | 0.00 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC100272217 | 0.15 | 0.17 | lasso | 3 | 0.17 | 8.2e-19 | 5.8 | 5.8 | 5.2e-09 | -0.18 | 1.00 | 0.00 | FALSE |
| 10 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LOC100272217 | 0.09 | 0.07 | lasso | 3 | 0.05 | 1.2e-03 | 5.8 | 5.8 | 5.2e-09 | -0.18 | 0.20 | 0.03 | FALSE |
| 11 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC100272217 | 0.26 | 0.19 | blup | 44 | 0.22 | 2.7e-24 | 5.8 | 5.8 | 7.7e-09 | -0.04 | 1.00 | 0.00 | TRUE |
| 12 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOC100272217 | 0.07 | 0.06 | lasso | 3 | 0.05 | 6.3e-07 | 5.8 | 5.8 | 5.2e-09 | -0.18 | 0.98 | 0.00 | FALSE |
| 13 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LOC100272217 | 0.07 | 0.02 | blup | 44 | 0.02 | 1.5e-03 | 10.3 | 9.0 | 2.5e-19 | -0.17 | 0.52 | 0.02 | FALSE |
| 14 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | LOC100272217 | 0.16 | 0.09 | lasso | 4 | 0.07 | 8.6e-04 | 5.8 | 5.6 | 1.8e-08 | -0.16 | 0.07 | 0.04 | TRUE |
| 15 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | LOC100272217 | 0.33 | 0.16 | lasso | 8 | 0.18 | 8.6e-08 | 5.8 | 7.2 | 5.2e-13 | -0.26 | 0.98 | 0.00 | TRUE |
| 16 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC100272217 | 0.25 | 0.17 | lasso | 6 | 0.17 | 1.5e-17 | 5.8 | 5.8 | 4.8e-09 | -0.15 | 1.00 | 0.00 | FALSE |
| 17 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LOC100272217 | 0.09 | 0.05 | enet | 8 | 0.04 | 3.7e-03 | 5.8 | 8.0 | 1.5e-15 | -0.28 | 0.02 | 0.10 | FALSE |
| 18 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | LOC100272217 | 0.26 | 0.10 | lasso | 4 | 0.13 | 2.1e-04 | 10.5 | -6.7 | 2.9e-11 | 0.65 | 0.02 | 0.49 | TRUE |
| 19 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LOC100272217 | 0.06 | 0.07 | lasso | 3 | 0.07 | 1.5e-05 | 5.8 | 5.8 | 5.2e-09 | -0.18 | 0.47 | 0.02 | FALSE |
| 20 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC100272217 | 0.25 | 0.19 | enet | 13 | 0.22 | 9.0e-21 | 5.8 | 6.4 | 2.0e-10 | -0.08 | 1.00 | 0.00 | FALSE |