[Hub]/) : Traits : Height : ← →

chr10:130,566,749-132,263,732

Best TWAS P=7.83e-19 · Best GWAS P=7.29e-18 conditioned to 0.132

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MGMT	0.29	0.27	lasso	14	0.31	6.0e-38	-8.1	7.9	3.6e-15	-0.82	0.15	0.85	FALSE
2	GTEx	Adipose Subcutaneous	MGMT	0.39	0.27	enet	30	0.48	1.2e-44	-8.4	7.6	3.9e-14	-0.84	0.03	0.97	FALSE
3	GTEx	Adipose Visceral Omentum	MGMT	0.39	0.16	enet	11	0.24	9.1e-13	-7.5	7.8	4.3e-15	-0.87	0.25	0.75	FALSE
4	GTEx	Adrenal Gland	MGMT	0.39	0.25	lasso	6	0.30	1.5e-11	-8.1	8.3	7.7e-17	-0.82	0.08	0.92	FALSE
5	GTEx	Artery Aorta	MGMT	0.50	0.28	enet	60	0.37	1.2e-21	-8.1	7.3	3.2e-13	-0.72	0.15	0.85	FALSE
6	GTEx	Artery Tibial	MGMT	0.42	0.30	enet	22	0.46	1.9e-40	-7.8	7.8	8.7e-15	-0.82	0.67	0.33	FALSE
7	GTEx	Brain Caudate basal ganglia	MGMT	0.40	0.40	lasso	2	0.36	4.7e-11	-7.5	7.5	5.3e-14	-0.84	0.14	0.86	FALSE
8	GTEx	Brain Cerebellar Hemisphere	MGMT	0.53	0.15	lasso	8	0.19	1.3e-05	-8.1	8.2	1.7e-16	-0.86	0.02	0.94	FALSE
9	GTEx	Brain Cerebellum	MGMT	0.38	0.17	enet	18	0.27	1.1e-08	-8.4	6.9	3.8e-12	-0.81	0.06	0.93	FALSE
10	GTEx	Brain Hypothalamus	MGMT	0.46	0.08	enet	46	0.00	3.4e-01	-8.1	5.6	1.9e-08	-0.51	0.07	0.69	FALSE
11	GTEx	Brain Nucleus accumbens basal ganglia	MGMT	0.32	0.29	lasso	1	0.21	2.4e-06	-8.4	8.4	6.0e-17	-0.97	0.02	0.97	FALSE
12	GTEx	Breast Mammary Tissue	MGMT	0.60	0.21	enet	13	0.33	1.6e-17	-7.5	7.8	5.0e-15	-0.84	0.29	0.71	FALSE
13	GTEx	Breast Mammary Tissue (Female)	MGMT	0.46	0.31	lasso	4	0.33	1.1e-10	-7.5	7.5	6.7e-14	-0.83	0.12	0.86	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	MGMT	0.57	0.03	lasso	22	0.20	3.4e-07	-2.2	6.9	4.0e-12	-0.80	0.05	0.94	FALSE
15	GTEx	Cells Transformed fibroblasts	MGMT	0.45	0.30	enet	31	0.42	4.8e-34	-8.4	8.2	3.2e-16	-0.86	0.03	0.97	FALSE
16	GTEx	Colon Sigmoid	MGMT	0.55	0.21	enet	29	0.29	9.1e-11	-7.5	7.1	9.8e-13	-0.69	0.28	0.72	FALSE
17	GTEx	Colon Transverse	MGMT	0.47	0.24	enet	58	0.35	1.6e-17	-7.5	6.7	1.7e-11	-0.78	0.14	0.86	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	MGMT	0.34	0.31	lasso	6	0.28	9.8e-11	-7.8	8.1	5.4e-16	-0.82	0.34	0.66	FALSE
19	GTEx	Esophagus Mucosa	MGMT	0.41	0.33	enet	37	0.38	2.3e-26	-7.5	8.0	1.1e-15	-0.83	0.40	0.60	FALSE
20	GTEx	Esophagus Muscularis	MGMT	0.50	0.29	enet	40	0.34	3.4e-21	-7.5	7.5	9.2e-14	-0.78	0.28	0.72	FALSE
21	GTEx	Heart Atrial Appendage	MGMT	0.41	0.17	enet	33	0.22	4.6e-10	-7.5	8.4	3.5e-17	-0.84	0.22	0.78	FALSE
22	GTEx	Heart Left Ventricle	MGMT	0.27	0.20	lasso	7	0.22	6.3e-12	-7.5	7.7	1.8e-14	-0.83	0.43	0.57	FALSE
23	GTEx	Liver	MGMT	0.46	0.39	lasso	4	0.42	8.2e-13	-7.5	8.3	9.9e-17	-0.93	0.01	0.99	FALSE
24	GTEx	Lung	MGMT	0.39	0.24	enet	28	0.33	5.5e-26	-7.5	8.0	1.6e-15	-0.81	0.73	0.27	FALSE
25	GTEx	Muscle Skeletal	MGMT	0.30	0.15	lasso	7	0.27	2.0e-26	-8.4	7.2	6.5e-13	-0.85	0.02	0.98	FALSE
26	GTEx	Nerve Tibial	MGMT	0.50	0.23	enet	46	0.42	6.9e-32	-8.4	7.6	2.3e-14	-0.81	0.04	0.96	FALSE
27	GTEx	Ovary	MGMT	0.52	0.09	enet	59	0.12	8.6e-04	-8.4	7.2	6.3e-13	-0.72	0.03	0.94	FALSE
28	GTEx	Pancreas	MGMT	0.32	0.03	lasso	7	0.17	8.0e-08	-7.5	7.8	9.2e-15	-0.72	0.06	0.91	FALSE
29	GTEx	Pituitary	MGMT	0.40	0.19	enet	9	0.23	1.9e-06	-8.4	7.3	2.5e-13	-0.85	0.05	0.91	FALSE
30	GTEx	Prostate	MGMT	0.25	0.13	lasso	4	0.20	9.4e-06	-8.1	8.5	1.8e-17	-0.85	0.07	0.82	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	MGMT	0.61	0.37	enet	93	0.45	5.4e-27	-7.5	6.7	2.3e-11	-0.70	0.74	0.26	FALSE
32	GTEx	Skin Sun Exposed Lower leg	MGMT	0.45	0.30	enet	42	0.46	1.6e-41	-7.8	8.3	1.3e-16	-0.83	0.51	0.49	FALSE
33	GTEx	Small Intestine Terminal Ileum	MGMT	0.31	0.14	enet	11	0.21	1.6e-05	-7.8	8.3	1.0e-16	-0.87	0.08	0.80	FALSE
34	GTEx	Spleen	MGMT	0.49	0.15	enet	53	0.04	4.1e-02	-7.8	5.6	2.3e-08	-0.74	0.10	0.71	FALSE
35	GTEx	Stomach	MGMT	0.33	0.20	enet	9	0.25	2.3e-12	-8.5	8.9	7.8e-19	-0.90	0.02	0.98	TRUE
36	GTEx	Testis	MGMT	0.49	0.34	lasso	5	0.35	2.8e-16	-7.5	7.8	5.8e-15	-0.88	0.57	0.43	FALSE
37	GTEx	Thyroid	MGMT	0.44	0.35	lasso	11	0.43	1.9e-35	-8.1	8.3	9.9e-17	-0.86	0.21	0.79	FALSE
38	GTEx	Vagina	MGMT	0.33	0.23	lasso	4	0.24	3.3e-06	-8.4	8.6	1.0e-17	-0.92	0.03	0.92	FALSE
39	GTEx	Whole Blood	MGMT	0.10	0.03	enet	10	0.04	2.5e-04	5.9	7.8	5.6e-15	-0.76	0.14	0.85	FALSE
40	METSIM	Adipose	MGMT	0.18	0.11	lasso	9	0.18	1.5e-25	-5.8	7.5	7.7e-14	-0.84	0.29	0.71	FALSE
41	NTR	Blood	MGMT	0.08	0.07	lasso	8	0.08	3.7e-24	-7.5	7.7	1.0e-14	-0.87	0.89	0.11	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	MGMT	0.41	0.38	enet	46	0.48	3.6e-69	-7.5	8.3	1.1e-16	-0.83	0.39	0.61	FALSE
43	YFS	Blood	MGMT	0.50	0.40	enet	94	0.55	1.6e-218	-7.5	8.0	8.7e-16	-0.76	0.97	0.03	FALSE
44	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MGMT	0.16	0.04	blup	235	0.08	2.6e-07	-5.4	6.2	6.1e-10	-0.54	0.24	0.75	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	MGMT	0.16	0.17	enet	22	0.21	2.4e-41	-7.5	7.9	2.3e-15	-0.86	0.93	0.07	FALSE
46	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MGMT	0.18	0.03	blup	239	0.12	2.3e-06	-7.5	6.9	4.6e-12	-0.73	0.17	0.80	FALSE
47	The Cancer Genome Atlas	Colon Adenocarcinoma	MGMT	0.24	0.09	blup	238	0.14	2.3e-08	-7.8	7.0	2.0e-12	-0.63	0.30	0.69	FALSE
48	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MGMT	0.10	0.09	enet	23	0.10	1.9e-11	-8.4	7.0	3.1e-12	-0.83	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MGMT	0.26	0.32	lasso	10	0.37	2.9e-43	-8.1	8.8	1.9e-18	-0.88	0.14	0.86	FALSE
50	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MGMT	0.40	0.24	enet	29	0.37	1.9e-22	-8.1	7.5	6.8e-14	-0.76	0.19	0.81	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	MGMT	0.13	0.07	lasso	5	0.10	2.4e-11	-7.5	7.0	2.2e-12	-0.80	0.40	0.60	FALSE
52	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MGMT	0.25	0.05	blup	234	0.12	1.9e-06	-7.5	7.4	1.4e-13	-0.68	0.05	0.90	FALSE
53	The Cancer Genome Atlas	Lung Adenocarcinoma	MGMT	0.11	0.07	enet	16	0.14	2.8e-16	-7.5	7.4	1.1e-13	-0.84	0.43	0.57	FALSE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MGMT	0.09	0.09	enet	9	0.09	8.4e-11	4.2	6.2	7.4e-10	-0.68	1.00	0.00	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MGMT	0.19	0.06	blup	239	0.09	1.1e-06	-7.5	6.5	6.8e-11	-0.66	0.37	0.62	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	MGMT	0.30	0.12	enet	30	0.22	2.0e-09	4.1	6.8	1.5e-11	-0.74	0.61	0.38	FALSE
57	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	MGMT	0.27	0.24	lasso	7	0.19	3.3e-08	-5.4	5.7	1.5e-08	-0.67	0.35	0.64	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	MGMT	0.39	0.31	enet	60	0.35	1.8e-37	-7.5	7.0	2.2e-12	-0.72	0.96	0.04	FALSE
59	The Cancer Genome Atlas	Soft Tissue Sarcoma	MGMT	0.14	0.05	blup	235	0.11	5.4e-07	-8.0	7.6	2.2e-14	-0.77	0.01	0.99	FALSE
60	The Cancer Genome Atlas	Stomach Adenocarcinoma	MGMT	0.15	0.08	lasso	4	0.10	7.5e-08	-7.5	7.5	6.0e-14	-0.85	0.02	0.98	FALSE
61	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MGMT	0.24	0.10	enet	13	0.13	2.6e-05	-7.5	6.5	8.4e-11	-0.58	0.14	0.46	FALSE
62	The Cancer Genome Atlas	Thyroid Carcinoma	MGMT	0.48	0.37	enet	52	0.48	2.0e-52	-7.5	7.4	1.0e-13	-0.77	0.85	0.15	FALSE