[Hub]/) : Traits : Height :

chr11:58,686,121-60,333,566

Best TWAS P=5.98e-13 · Best GWAS P=2.88e-12 conditioned to 0.46

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous STX3 0.13 0.06 lasso 2 0.06 1.2e-05 -5.8 6.0 2.4e-09 -0.79 0.21 0.76 FALSE
2 GTEx Artery Tibial STX3 0.06 0.09 lasso 2 0.08 1.3e-06 -5.8 5.8 7.8e-09 -0.77 0.77 0.22 FALSE
3 GTEx Brain Hippocampus AP000442.1 0.20 0.17 lasso 2 0.09 4.3e-03 -5.7 -5.9 4.4e-09 0.77 0.11 0.28 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia AP000442.1 0.21 0.00 lasso 2 0.02 9.8e-02 -5.8 -5.8 8.6e-09 0.77 0.08 0.75 FALSE
5 GTEx Muscle Skeletal AP000442.1 0.07 0.05 enet 9 0.05 4.9e-06 -6.9 -6.2 4.3e-10 0.84 0.01 0.98 FALSE
6 GTEx Nerve Tibial STX3 0.16 0.15 enet 12 0.15 4.6e-11 -5.8 6.3 3.7e-10 -0.84 0.45 0.55 FALSE
7 GTEx Pituitary AP000442.1 0.24 0.28 enet 15 0.24 1.3e-06 -6.8 -6.5 1.0e-10 0.88 0.02 0.98 FALSE
8 GTEx Testis STX3 0.14 0.03 lasso 6 0.06 9.7e-04 -6.2 5.3 1.4e-07 -0.66 0.46 0.30 FALSE
9 NTR Blood TCN1 0.03 0.02 blup 373 0.02 6.2e-06 -4.7 -7.2 6.0e-13 0.42 0.96 0.01 TRUE
10 ROSMAP Brain Pre-frontal Cortex STX3 0.07 0.08 lasso 9 0.08 1.6e-10 -7.0 6.9 4.3e-12 -0.92 0.02 0.98 FALSE
11 YFS Blood STX3 0.08 0.10 lasso 6 0.09 3.4e-29 -6.9 6.9 4.2e-12 -0.92 0.01 0.99 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma MS4A4A 0.06 0.04 blup 79 0.05 1.1e-03 -5.2 -5.5 3.9e-08 0.19 0.05 0.90 FALSE
13 The Cancer Genome Atlas Esophageal Carcinoma PATL1 0.14 0.04 blup 32 0.06 4.3e-03 -6.9 6.6 3.5e-11 -0.90 0.00 0.87 TRUE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MS4A4A 0.05 0.07 lasso 2 0.06 4.6e-07 -5.1 -5.1 3.0e-07 0.19 0.02 0.98 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma MS4A4A 0.05 0.05 blup 79 0.05 1.3e-06 -4.8 -5.2 2.2e-07 0.20 0.03 0.96 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MS4A4A 0.03 0.02 blup 79 0.02 4.2e-03 -4.8 -5.5 3.1e-08 0.19 0.05 0.85 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MS4A4A 0.06 0.08 lasso 5 0.06 8.2e-05 -5.1 -5.2 2.6e-07 0.18 0.02 0.97 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma MS4A4A 0.07 0.03 blup 79 0.04 2.8e-05 -5.6 -5.2 2.4e-07 0.17 0.00 0.99 FALSE