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chr11:94,805,896-96,276,010

Best TWAS P=6.83e-08 · Best GWAS P=5.82e-12 conditioned to 8.51e-13

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM76B	0.06	0.02	lasso	3	0.01	8.1e-03	5.3	-5.4	7.4e-08	0.07	0.83	0.03	FALSE
2	GTEx	Adipose Subcutaneous	CEP57	0.17	0.12	enet	26	0.14	3.1e-11	5.3	5.2	1.5e-07	-0.05	0.98	0.02	FALSE
3	GTEx	Brain Cerebellar Hemisphere	AP001877.1	0.29	0.24	lasso	7	0.25	5.0e-07	4.8	5.2	2.5e-07	-0.03	0.88	0.02	FALSE
4	GTEx	Brain Frontal Cortex BA9	AP001877.1	0.20	-0.01	enet	21	0.00	4.6e-01	5.3	5.4	7.3e-08	-0.08	0.11	0.07	FALSE
5	GTEx	Colon Transverse	CEP57	0.12	0.11	lasso	3	0.11	6.8e-06	5.3	5.3	1.4e-07	-0.05	0.86	0.05	FALSE
6	GTEx	Esophagus Mucosa	CEP57	0.14	0.14	lasso	3	0.10	6.0e-07	5.3	5.4	6.8e-08	-0.05	0.97	0.03	TRUE
7	GTEx	Esophagus Muscularis	CEP57	0.15	0.05	enet	21	0.06	9.0e-05	5.3	5.4	8.2e-08	-0.06	0.95	0.02	FALSE
8	GTEx	Esophagus Muscularis	AP001877.1	0.17	0.09	lasso	6	0.10	6.2e-07	5.3	5.3	1.0e-07	-0.02	0.94	0.03	FALSE
9	GTEx	Muscle Skeletal	CEP57	0.15	0.18	lasso	9	0.18	1.8e-17	5.2	5.1	2.9e-07	-0.01	0.98	0.02	FALSE
10	GTEx	Nerve Tibial	MTMR2	0.14	0.10	enet	16	0.08	2.0e-06	4.8	-5.3	1.3e-07	0.05	0.98	0.02	FALSE
11	GTEx	Nerve Tibial	CEP57	0.15	0.08	lasso	6	0.07	1.9e-05	5.3	5.3	9.1e-08	-0.04	0.97	0.02	FALSE
12	GTEx	Nerve Tibial	AP001877.1	0.15	0.05	lasso	3	0.05	1.6e-04	5.3	5.2	2.1e-07	-0.03	0.93	0.02	FALSE
13	GTEx	Pancreas	CEP57	0.19	0.10	lasso	13	0.08	3.6e-04	5.4	5.2	1.8e-07	-0.06	0.85	0.03	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CEP57	0.14	0.06	enet	10	0.05	9.6e-04	3.3	5.3	1.1e-07	-0.09	0.95	0.02	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CEP57	0.19	0.14	enet	24	0.16	4.1e-13	5.3	5.2	2.2e-07	-0.02	0.97	0.03	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	AP001877.1	0.17	0.27	lasso	12	0.27	3.6e-35	5.3	5.2	2.0e-07	-0.03	0.98	0.02	FALSE
17	YFS	Blood	FAM76B	0.14	0.25	lasso	10	0.26	8.1e-83	5.1	-5.2	1.7e-07	0.03	0.98	0.02	FALSE