[Hub]/) : Traits : Height :

chr12:69,045,442-70,687,630

Best TWAS P=3.3e-83 · Best GWAS P=8.29e-108 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex YEATS4 0.37 0.23 lasso 7 0.45 4.6e-61 8.32 -6.3 2.6e-10 0.06 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous LYZ 0.15 0.08 lasso 3 0.09 5.4e-08 -7.13 -7.4 1.6e-13 -0.06 1.00 0.00 TRUE
3 GTEx Adipose Subcutaneous YEATS4 0.32 0.28 enet 17 0.30 1.0e-24 8.32 -8.7 2.3e-18 -0.06 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous RP11-1143G9.4 0.12 0.04 lasso 4 0.04 5.0e-04 -7.13 -7.0 1.9e-12 -0.03 0.81 0.01 FALSE
5 GTEx Adipose Visceral Omentum LYZ 0.17 0.12 enet 12 0.12 5.2e-07 7.56 -7.2 8.3e-13 -0.11 0.98 0.00 FALSE
6 GTEx Adipose Visceral Omentum YEATS4 0.32 0.30 lasso 3 0.29 2.7e-15 8.32 -8.2 1.8e-16 -0.10 1.00 0.00 FALSE
7 GTEx Adipose Visceral Omentum RP11-1143G9.4 0.16 0.13 enet 10 0.13 2.3e-07 7.56 -7.9 2.3e-15 -0.15 0.99 0.00 FALSE
8 GTEx Adrenal Gland LYZ 0.24 0.22 enet 14 0.23 6.9e-09 7.59 -8.1 7.1e-16 -0.17 0.97 0.00 FALSE
9 GTEx Adrenal Gland RP11-1143G9.4 0.18 0.15 enet 11 0.17 8.5e-07 8.32 -7.7 1.2e-14 -0.15 0.88 0.01 FALSE
10 GTEx Artery Aorta LYZ 0.22 0.08 lasso 6 0.11 1.1e-06 -2.05 -6.5 9.1e-11 -0.14 0.94 0.00 FALSE
11 GTEx Artery Aorta YEATS4 0.25 0.12 enet 11 0.21 5.0e-12 -2.35 -5.7 1.5e-08 0.10 0.99 0.00 FALSE
12 GTEx Artery Aorta RP11-1143G9.4 0.20 0.06 lasso 5 0.08 2.2e-05 9.35 -7.6 4.3e-14 -0.15 0.76 0.01 FALSE
13 GTEx Artery Tibial LYZ 0.18 0.12 enet 22 0.13 2.3e-10 7.64 -5.3 1.1e-07 -0.01 1.00 0.00 FALSE
14 GTEx Artery Tibial YEATS4 0.37 0.23 enet 21 0.35 3.2e-28 8.32 -7.4 1.1e-13 -0.01 1.00 0.00 FALSE
15 GTEx Artery Tibial RP11-1143G9.4 0.15 0.11 lasso 5 0.11 7.5e-09 8.32 -6.1 1.1e-09 -0.06 1.00 0.00 TRUE
16 GTEx Brain Cerebellar Hemisphere FRS2 0.34 -0.01 enet 25 0.07 9.2e-03 -0.24 8.6 6.1e-18 0.15 0.08 0.10 FALSE
17 GTEx Brain Cortex YEATS4 0.22 0.11 enet 18 0.09 1.8e-03 8.83 -9.3 1.5e-20 -0.08 0.36 0.05 FALSE
18 GTEx Brain Frontal Cortex BA9 YEATS4 0.28 0.00 lasso 4 0.08 4.1e-03 8.32 -6.8 9.2e-12 0.03 0.13 0.05 FALSE
19 GTEx Brain Hypothalamus YEATS4 0.21 0.00 enet 21 0.03 6.1e-02 -7.08 -9.7 4.9e-22 -0.23 0.08 0.06 TRUE
20 GTEx Brain Nucleus accumbens basal ganglia YEATS4 0.29 0.25 enet 8 0.17 2.6e-05 8.32 -8.5 2.0e-17 -0.07 0.42 0.03 FALSE
21 GTEx Breast Mammary Tissue YEATS4 0.44 0.30 lasso 9 0.29 2.9e-15 8.32 -7.5 5.6e-14 -0.08 1.00 0.00 FALSE
22 GTEx Breast Mammary Tissue (Male) YEATS4 0.25 0.20 lasso 6 0.13 6.1e-04 7.56 -7.5 8.1e-14 -0.17 0.10 0.27 FALSE
23 GTEx Breast Mammary Tissue (Female) YEATS4 0.28 0.26 enet 12 0.19 2.2e-06 8.32 -7.5 5.6e-14 -0.08 0.74 0.02 FALSE
24 GTEx Cells EBV-transformed lymphocytes YEATS4 0.47 0.43 lasso 6 0.43 1.8e-15 7.64 7.5 4.7e-14 0.17 1.00 0.00 FALSE
25 GTEx Cells EBV-transformed lymphocytes CCT2 0.27 0.15 lasso 8 0.10 5.0e-04 7.59 -7.2 7.9e-13 -0.18 0.28 0.06 FALSE
26 GTEx Colon Sigmoid YEATS4 0.20 0.26 lasso 2 0.25 2.2e-09 8.32 -8.3 8.8e-17 -0.11 0.95 0.00 FALSE
27 GTEx Colon Transverse YEATS4 0.17 0.06 enet 11 0.10 1.2e-05 7.41 -7.5 8.8e-14 0.01 0.67 0.02 FALSE
28 GTEx Esophagus Mucosa YEATS4 0.26 0.14 lasso 7 0.12 2.2e-08 8.32 -7.5 7.2e-14 -0.07 1.00 0.00 FALSE
29 GTEx Esophagus Muscularis LYZ 0.18 0.13 enet 11 0.21 6.1e-13 7.41 -6.8 1.2e-11 -0.11 1.00 0.00 FALSE
30 GTEx Esophagus Muscularis YEATS4 0.40 0.23 enet 12 0.34 3.7e-21 8.32 -7.1 1.7e-12 0.01 1.00 0.00 FALSE
31 GTEx Esophagus Muscularis RP11-1143G9.4 0.15 0.10 enet 8 0.16 3.4e-10 8.32 -7.1 1.1e-12 -0.11 0.99 0.00 FALSE
32 GTEx Heart Atrial Appendage LYZ 0.20 0.20 enet 17 0.16 1.7e-07 7.41 -9.0 2.4e-19 -0.11 0.98 0.00 FALSE
33 GTEx Heart Atrial Appendage YEATS4 0.28 0.19 lasso 4 0.20 3.7e-09 8.32 -8.1 6.8e-16 -0.05 0.95 0.00 FALSE
34 GTEx Heart Atrial Appendage RP11-1143G9.4 0.14 0.08 enet 12 0.00 3.9e-01 7.41 -7.6 2.1e-14 -0.09 0.67 0.02 FALSE
35 GTEx Heart Left Ventricle YEATS4 0.21 0.18 enet 9 0.11 1.8e-06 -7.13 -8.0 1.0e-15 -0.08 1.00 0.00 FALSE
36 GTEx Lung LYZ 0.30 0.25 enet 22 0.27 1.1e-20 7.56 -7.7 1.8e-14 -0.15 1.00 0.00 FALSE
37 GTEx Lung YEATS4 0.13 0.18 lasso 6 0.16 1.1e-12 8.32 -8.6 1.2e-17 -0.11 1.00 0.00 FALSE
38 GTEx Lung RP11-1143G9.4 0.30 0.24 enet 23 0.27 1.5e-20 8.32 -7.6 3.2e-14 -0.15 1.00 0.00 FALSE
39 GTEx Muscle Skeletal YEATS4 0.24 0.25 lasso 6 0.24 8.3e-24 8.32 -8.2 2.8e-16 -0.10 1.00 0.00 FALSE
40 GTEx Nerve Tibial LYZ 0.11 0.06 enet 28 0.09 5.1e-07 7.59 -5.8 5.9e-09 -0.14 0.98 0.00 FALSE
41 GTEx Nerve Tibial YEATS4 0.32 0.22 enet 15 0.32 2.6e-23 8.32 -6.2 4.8e-10 0.07 1.00 0.00 FALSE
42 GTEx Nerve Tibial RP11-1143G9.4 0.10 0.03 enet 31 0.06 5.2e-05 7.59 -5.1 2.9e-07 -0.10 0.83 0.01 FALSE
43 GTEx Ovary YEATS4 0.28 0.21 lasso 3 0.14 2.9e-04 8.32 -8.3 1.3e-16 -0.08 0.13 0.05 FALSE
44 GTEx Prostate YEATS4 0.40 0.01 lasso 6 0.06 1.6e-02 -1.81 -6.5 7.8e-11 0.07 0.11 0.05 FALSE
45 GTEx Skin Not Sun Exposed Suprapubic YEATS4 0.36 0.37 lasso 3 0.37 3.9e-21 8.32 -8.0 9.9e-16 -0.09 1.00 0.00 FALSE
46 GTEx Skin Not Sun Exposed Suprapubic FRS2 0.20 0.00 lasso 5 0.00 2.4e-01 2.98 5.7 1.2e-08 0.19 0.06 0.52 TRUE
47 GTEx Skin Sun Exposed Lower leg LYZ 0.09 0.10 enet 13 0.10 8.0e-09 8.32 -9.9 2.9e-23 -0.17 1.00 0.00 TRUE
48 GTEx Skin Sun Exposed Lower leg YEATS4 0.30 0.32 enet 19 0.31 6.6e-26 8.32 -8.4 3.3e-17 -0.14 1.00 0.00 FALSE
49 GTEx Skin Sun Exposed Lower leg RP11-1143G9.4 0.08 0.07 lasso 5 0.07 2.1e-06 8.32 -8.7 2.8e-18 -0.11 0.99 0.00 FALSE
50 GTEx Spleen LYZ 0.30 0.14 enet 25 0.09 2.5e-03 7.56 -7.8 4.4e-15 -0.13 0.36 0.04 FALSE
51 GTEx Spleen RP11-1143G9.4 0.29 0.09 lasso 11 0.09 2.9e-03 7.56 -8.9 4.2e-19 -0.15 0.32 0.04 FALSE
52 GTEx Stomach YEATS4 0.19 0.16 lasso 8 0.12 2.7e-06 8.32 -8.1 7.6e-16 -0.02 0.85 0.02 FALSE
53 GTEx Thyroid LYZ 0.09 0.01 enet 12 0.03 1.9e-03 7.41 -7.5 5.3e-14 -0.04 0.70 0.01 FALSE
54 GTEx Thyroid YEATS4 0.32 0.37 lasso 4 0.37 1.0e-29 8.32 -8.2 1.8e-16 -0.08 1.00 0.00 FALSE
55 GTEx Thyroid FRS2 0.30 0.16 lasso 6 0.17 8.8e-13 22.06 19.3 3.3e-83 0.93 0.00 1.00 TRUE
56 GTEx Thyroid RP11-1143G9.4 0.08 0.04 enet 9 0.02 6.8e-03 7.41 -8.3 1.2e-16 -0.07 0.79 0.01 FALSE
57 GTEx Uterus YEATS4 0.38 0.29 enet 15 0.11 3.2e-03 8.32 -7.7 1.6e-14 -0.08 0.22 0.05 FALSE
58 GTEx Vagina YEATS4 0.45 0.13 lasso 6 0.18 8.2e-05 8.32 -8.2 2.1e-16 -0.14 0.19 0.09 FALSE
59 GTEx Whole Blood LYZ 0.18 0.12 enet 17 0.13 6.0e-12 -7.13 -7.0 2.3e-12 -0.11 1.00 0.00 FALSE
60 GTEx Whole Blood RP11-1143G9.4 0.15 0.08 enet 18 0.08 1.2e-07 -7.13 -7.1 1.2e-12 -0.10 1.00 0.00 FALSE
61 METSIM Adipose LYZ 0.06 0.06 enet 9 0.07 2.5e-10 8.19 -8.3 8.7e-17 -0.17 1.00 0.00 FALSE
62 METSIM Adipose YEATS4 0.24 0.29 lasso 2 0.28 8.4e-42 8.32 -8.2 1.6e-16 -0.10 1.00 0.00 FALSE
63 NTR Blood LYZ 0.19 0.22 lasso 6 0.26 2.6e-83 8.32 -8.7 2.7e-18 -0.07 1.00 0.00 FALSE
64 YFS Blood LYZ 0.57 0.68 enet 49 0.73 0.0e+00 7.41 -8.1 3.7e-16 -0.11 1.00 0.00 FALSE
65 YFS Blood YEATS4 0.28 0.26 lasso 6 0.32 1.5e-108 8.32 -6.7 2.9e-11 -0.05 1.00 0.00 FALSE
66 The Cancer Genome Atlas Bladder Urothelial Carcinoma LYZ 0.06 0.03 blup 42 0.05 6.9e-05 8.37 -8.4 3.5e-17 -0.09 0.04 0.96 FALSE
67 The Cancer Genome Atlas Breast Invasive Carcinoma LYZ 0.08 0.12 enet 7 0.14 1.4e-27 -7.13 -8.6 1.0e-17 -0.10 0.00 1.00 FALSE
68 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LYZ 0.20 0.07 enet 22 0.08 6.9e-05 7.41 -5.9 4.2e-09 -0.05 0.03 0.96 FALSE
69 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma YEATS4 0.11 0.02 blup 74 0.03 9.0e-03 11.94 9.2 3.8e-20 0.18 0.09 0.03 FALSE
70 The Cancer Genome Atlas Colon Adenocarcinoma YEATS4 0.10 0.00 blup 73 0.01 9.1e-02 14.85 5.8 8.5e-09 0.45 0.04 0.51 FALSE
71 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CPSF6 0.05 0.03 lasso 4 0.03 3.0e-04 -6.77 7.8 5.1e-15 0.12 0.03 0.97 FALSE
72 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LYZ 0.08 0.10 enet 9 0.12 1.4e-13 8.80 -8.4 3.0e-17 -0.09 0.00 1.00 FALSE
73 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LYZ 0.13 0.16 enet 8 0.17 2.6e-18 -7.13 -8.4 3.0e-17 -0.13 0.08 0.92 FALSE
74 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma YEATS4 0.26 0.18 enet 17 0.29 4.9e-33 7.51 -7.7 9.5e-15 0.04 1.00 0.00 FALSE
75 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LYZ 0.17 0.22 lasso 7 0.25 1.6e-14 -7.13 -8.1 7.7e-16 -0.08 0.11 0.89 FALSE
76 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma YEATS4 0.12 0.12 lasso 5 0.17 3.4e-10 8.37 -7.2 8.1e-13 0.03 0.95 0.00 FALSE
77 The Cancer Genome Atlas Brain Lower Grade Glioma LYZ 0.06 0.06 enet 6 0.06 7.5e-08 -7.13 -7.7 1.5e-14 -0.13 0.11 0.89 FALSE
78 The Cancer Genome Atlas Brain Lower Grade Glioma YEATS4 0.24 0.14 lasso 7 0.26 1.8e-29 -1.74 -6.1 9.8e-10 0.06 1.00 0.00 FALSE
79 The Cancer Genome Atlas Liver Hepatocellular Carcinoma YEATS4 0.14 -0.01 blup 75 0.03 1.3e-02 -2.38 -5.8 8.4e-09 0.09 0.12 0.03 FALSE
80 The Cancer Genome Atlas Lung Adenocarcinoma LYZ 0.12 0.10 lasso 2 0.10 9.5e-12 8.37 -8.0 1.4e-15 -0.12 0.09 0.91 FALSE
81 The Cancer Genome Atlas Lung Adenocarcinoma YEATS4 0.03 0.00 blup 73 0.01 7.3e-03 -2.38 -8.7 4.8e-18 0.03 0.04 0.03 FALSE
82 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LYZ 0.10 0.08 enet 8 0.10 2.4e-11 8.80 -8.3 7.0e-17 -0.13 0.00 1.00 FALSE
83 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LYZ 0.19 0.16 enet 10 0.18 4.5e-12 7.59 -7.8 6.8e-15 -0.15 0.06 0.94 FALSE
84 The Cancer Genome Atlas Pancreatic Adenocarcinoma YEATS4 0.19 0.04 enet 15 0.08 4.2e-04 8.37 -8.0 1.3e-15 -0.01 0.22 0.04 FALSE
85 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LYZ 0.29 0.14 lasso 6 0.26 6.8e-11 8.80 -8.6 1.2e-17 -0.14 0.00 1.00 FALSE
86 The Cancer Genome Atlas Prostate Adenocarcinoma LYZ 0.09 0.12 enet 9 0.14 3.9e-14 7.51 -8.1 4.4e-16 -0.14 0.42 0.58 FALSE
87 The Cancer Genome Atlas Prostate Adenocarcinoma YEATS4 0.18 0.15 lasso 11 0.21 1.1e-21 8.32 -7.6 2.4e-14 0.00 1.00 0.00 FALSE
88 The Cancer Genome Atlas Soft Tissue Sarcoma LYZ 0.06 0.02 blup 43 0.03 7.4e-03 -7.13 -8.7 4.5e-18 -0.07 0.00 0.82 FALSE
89 The Cancer Genome Atlas Skin Cutaneous Melanoma LYZ 0.12 0.09 blup 42 0.07 7.7e-03 -7.13 -7.5 4.5e-14 -0.12 0.02 0.38 FALSE
90 The Cancer Genome Atlas Stomach Adenocarcinoma LYZ 0.07 0.07 enet 6 0.08 4.1e-06 7.41 -7.0 2.7e-12 -0.10 0.38 0.36 FALSE
91 The Cancer Genome Atlas Testicular Germ Cell Tumors LYZ 0.17 0.17 lasso 4 0.19 2.2e-07 7.41 -8.2 2.4e-16 -0.08 0.01 0.99 FALSE
92 The Cancer Genome Atlas Thyroid Carcinoma LYZ 0.05 0.05 lasso 2 0.05 2.1e-05 8.83 -8.8 9.3e-19 -0.11 0.00 1.00 FALSE
93 The Cancer Genome Atlas Thyroid Carcinoma YEATS4 0.39 0.27 enet 12 0.47 1.2e-50 8.37 -6.3 3.8e-10 0.07 1.00 0.00 FALSE
94 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma LYZ 0.16 0.12 enet 13 0.13 2.3e-04 8.32 -7.9 3.2e-15 -0.13 0.02 0.93 FALSE