Best TWAS P=8.33e-08 · Best GWAS P=4.69e-11 conditioned to 5.56e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | UGGT2 | 0.16 | 0.02 | enet | 8 | 0.05 | 1.2e-02 | 3.7 | -5.2 | 2.3e-07 | -0.87 | 0.05 | 0.82 | FALSE |
2 | GTEx | Artery Tibial | UGGT2 | 0.07 | 0.02 | lasso | 6 | 0.03 | 1.7e-03 | -4.2 | -5.4 | 8.3e-08 | -0.67 | 0.32 | 0.61 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UGGT2 | 0.09 | 0.10 | blup | 82 | 0.12 | 5.7e-14 | 3.7 | -5.3 | 1.3e-07 | -0.84 | 0.09 | 0.91 | FALSE |