Best TWAS P=1.3e-12 · Best GWAS P=4.54e-17 conditioned to 1.49e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | MEG3 | 0.05 | 0.01 | lasso | 8 | 0.02 | 2.4e-04 | 4.5 | -6.3 | 3.2e-10 | -0.09 | 0.60 | 0.01 | FALSE |
2 | YFS | Blood | MEG3 | 0.15 | 0.14 | lasso | 6 | 0.15 | 4.6e-48 | 7.1 | -7.1 | 1.3e-12 | -0.33 | 0.94 | 0.06 | TRUE |