Best TWAS P=1.76e-09 · Best GWAS P=1.21e-46 conditioned to 4.7e-36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | IFI27L2 | 0.11 | 0.01 | enet | 16 | 0.05 | 8.4e-07 | 1.27 | -6.0 | 1.8e-09 | -0.15 | 0.08 | 0.73 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SERPINA1 | 0.07 | 0.01 | enet | 24 | 0.03 | 3.7e-04 | 0.99 | -5.7 | 1.2e-08 | -0.13 | 0.06 | 0.06 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SERPINA5 | 0.04 | 0.01 | blup | 114 | 0.01 | 3.5e-02 | 4.83 | -5.3 | 1.1e-07 | -0.06 | 0.01 | 0.85 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | GSC | 0.08 | 0.07 | lasso | 2 | 0.06 | 2.8e-06 | 5.33 | 5.3 | 8.7e-08 | 0.03 | 0.00 | 1.00 | TRUE |