Best TWAS P=6.08e-11 · Best GWAS P=1.69e-11 conditioned to 7.17e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | C15orf65 | 0.14 | 0.04 | enet | 30 | 0.08 | 1.8e-06 | -5.7 | -6.3 | 3.6e-10 | 0.01 | 0.61 | 0.36 | FALSE |
| 2 | GTEx | Pancreas | C15orf65 | 0.13 | 0.07 | enet | 5 | 0.05 | 4.3e-03 | -4.6 | -5.8 | 7.4e-09 | -0.01 | 0.24 | 0.21 | FALSE |
| 3 | GTEx | Uterus | C15orf65 | 0.33 | 0.02 | lasso | 13 | 0.02 | 1.1e-01 | -5.9 | -6.2 | 6.8e-10 | -0.09 | 0.06 | 0.07 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PIGB | 0.06 | 0.00 | blup | 47 | 0.02 | 4.4e-03 | 4.9 | -6.5 | 6.1e-11 | 0.03 | 0.01 | 0.34 | TRUE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PIGB | 0.03 | 0.01 | blup | 47 | 0.02 | 1.6e-03 | 4.9 | -6.5 | 1.0e-10 | 0.06 | 0.06 | 0.27 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PIGB | 0.12 | 0.05 | blup | 47 | 0.08 | 6.8e-08 | 4.9 | -5.4 | 6.2e-08 | 0.07 | 0.58 | 0.18 | FALSE |