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chr16:11,326,785-13,588,335

Best TWAS P=6.25e-10 · Best GWAS P=6.91e-09 conditioned to 0.298

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-166B2.1	0.49	0.38	enet	9	0.38	4.6e-33	-5.3	-5.5	2.8e-08	-0.78	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	RP11-166B2.1	0.40	0.23	enet	12	0.20	1.6e-10	-5.3	-5.3	1.2e-07	-0.76	0.01	0.99	FALSE
3	GTEx	Adrenal Gland	RP11-166B2.1	0.46	0.43	lasso	3	0.43	1.0e-16	-5.3	-5.2	1.9e-07	-0.70	0.01	0.99	FALSE
4	GTEx	Artery Aorta	RP11-166B2.1	0.42	0.31	lasso	9	0.28	1.5e-15	-5.3	-5.2	1.6e-07	-0.70	0.01	0.99	FALSE
5	GTEx	Artery Tibial	RP11-166B2.1	0.58	0.27	lasso	10	0.22	6.1e-17	-5.3	-5.2	1.6e-07	-0.73	0.01	0.99	FALSE
6	GTEx	Brain Caudate basal ganglia	RP11-166B2.1	0.78	0.59	lasso	9	0.61	8.9e-22	-5.3	-5.6	2.4e-08	-0.78	0.01	0.99	FALSE
7	GTEx	Brain Cerebellar Hemisphere	RP11-166B2.1	0.56	0.48	lasso	4	0.52	1.6e-15	-5.3	-5.3	1.2e-07	-0.77	0.01	0.99	FALSE
8	GTEx	Brain Cerebellum	RP11-166B2.1	0.46	0.33	lasso	6	0.32	4.3e-10	-5.3	-5.3	1.2e-07	-0.72	0.01	0.99	FALSE
9	GTEx	Brain Cortex	RP11-166B2.1	0.64	0.46	enet	19	0.44	1.1e-13	-5.3	-5.5	3.8e-08	-0.76	0.01	0.99	FALSE
10	GTEx	Brain Hippocampus	RP11-166B2.1	0.59	0.31	lasso	7	0.39	2.8e-10	-5.3	-5.8	5.2e-09	-0.84	0.01	0.99	TRUE
11	GTEx	Brain Hypothalamus	RP11-166B2.1	0.61	0.55	lasso	4	0.50	1.3e-13	-5.3	-5.5	3.6e-08	-0.76	0.01	0.99	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	RP11-166B2.1	0.78	0.53	enet	33	0.50	1.6e-15	-5.3	-5.5	4.0e-08	-0.72	0.01	0.99	FALSE
13	GTEx	Brain Putamen basal ganglia	RP11-166B2.1	0.57	0.59	lasso	5	0.56	4.9e-16	-5.3	-5.2	1.7e-07	-0.69	0.01	0.99	FALSE
14	GTEx	Breast Mammary Tissue	RP11-166B2.1	0.55	0.42	lasso	4	0.41	1.1e-22	-5.3	-5.4	6.6e-08	-0.71	0.01	0.99	FALSE
15	GTEx	Breast Mammary Tissue (Male)	RP11-166B2.1	0.39	0.28	lasso	3	0.27	5.5e-07	-5.3	-5.3	1.4e-07	-0.70	0.01	0.90	FALSE
16	GTEx	Breast Mammary Tissue (Female)	RP11-166B2.1	0.39	0.40	lasso	2	0.38	1.9e-12	-5.3	-5.3	1.2e-07	-0.69	0.01	0.99	FALSE
17	GTEx	Cells Transformed fibroblasts	RP11-166B2.1	0.57	0.52	enet	17	0.55	1.0e-48	-5.3	-5.2	2.0e-07	-0.72	0.01	0.99	FALSE
18	GTEx	Colon Sigmoid	RP11-166B2.1	0.31	0.33	lasso	1	0.32	8.0e-12	-5.3	-5.3	1.2e-07	-0.70	0.01	0.99	FALSE
19	GTEx	Colon Transverse	RP11-166B2.1	0.24	0.22	lasso	2	0.22	9.4e-11	-5.3	-5.3	1.2e-07	-0.70	0.01	0.99	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	RP11-166B2.1	0.67	0.42	lasso	13	0.39	2.2e-15	-5.3	-5.2	2.6e-07	-0.75	0.01	0.99	FALSE
21	GTEx	Esophagus Muscularis	RP11-166B2.1	0.52	0.40	lasso	7	0.38	5.5e-24	-5.3	-5.2	2.2e-07	-0.70	0.01	0.99	FALSE
22	GTEx	Heart Atrial Appendage	RP11-166B2.1	0.36	0.38	lasso	3	0.37	1.5e-17	-5.3	-5.4	8.1e-08	-0.73	0.01	0.99	FALSE
23	GTEx	Heart Left Ventricle	RP11-166B2.1	0.34	0.21	lasso	4	0.22	3.5e-12	-5.3	-5.5	3.8e-08	-0.79	0.01	0.99	FALSE
24	GTEx	Muscle Skeletal	RP11-166B2.1	0.18	0.18	lasso	3	0.17	3.9e-16	-5.3	-5.5	4.3e-08	-0.75	0.01	0.99	FALSE
25	GTEx	Nerve Tibial	CPPED1	0.24	0.10	lasso	5	0.07	2.1e-05	-5.6	-6.2	6.3e-10	-0.05	0.00	1.00	TRUE
26	GTEx	Nerve Tibial	RP11-166B2.1	0.50	0.48	lasso	3	0.47	5.2e-37	-5.3	-5.4	7.4e-08	-0.74	0.01	0.99	FALSE
27	GTEx	Ovary	RP11-166B2.1	0.45	0.23	enet	26	0.33	7.6e-09	-5.3	-5.7	1.5e-08	-0.73	0.01	0.97	FALSE
28	GTEx	Pancreas	RP11-166B2.1	0.46	0.37	lasso	4	0.35	1.2e-15	-5.3	-5.4	8.0e-08	-0.71	0.01	0.99	FALSE
29	GTEx	Pituitary	RP11-166B2.1	0.41	0.24	lasso	3	0.18	2.3e-05	-5.3	-5.5	3.0e-08	-0.77	0.01	0.98	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	RP11-166B2.1	0.27	0.30	lasso	2	0.29	1.6e-16	-5.3	-5.3	1.2e-07	-0.70	0.01	0.99	FALSE
31	GTEx	Skin Sun Exposed Lower leg	RP11-166B2.1	0.43	0.36	lasso	2	0.35	2.4e-30	-5.3	-5.4	7.9e-08	-0.73	0.01	0.99	FALSE
32	GTEx	Thyroid	RP11-166B2.1	0.37	0.32	lasso	5	0.31	3.1e-24	-5.3	-5.4	6.9e-08	-0.73	0.01	0.99	FALSE
33	GTEx	Whole Blood	RP11-166B2.1	0.21	0.14	lasso	3	0.13	3.2e-12	-5.3	-5.3	9.6e-08	-0.72	0.01	0.99	FALSE
34	METSIM	Adipose	RP11-166B2.1	0.37	0.42	lasso	1	0.42	8.2e-69	-5.3	-5.3	1.2e-07	-0.70	0.02	0.98	FALSE
35	ROSMAP	Brain Pre-frontal Cortex	RP11-166B2.1	0.17	0.16	bslmm	462	0.16	5.5e-20	-5.3	-5.2	2.2e-07	-0.66	0.02	0.98	FALSE