[Hub]/) : Traits : Height :

chr16:13,697,975-16,353,166

Best TWAS P=1.55e-40 · Best GWAS P=2.41e-50 conditioned to 2.02e-34

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PDXDC1 0.17 0.07 enet 17 0.10 1.3e-11 -4.5 -5.8 6.3e-09 0.04 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex RRN3 0.11 0.08 enet 12 0.12 3.3e-14 6.4 5.5 4.9e-08 -0.13 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -9.5 10.1 4.6e-24 -0.12 0.01 0.97 FALSE
4 GTEx Adipose Visceral Omentum PKD1P6 0.26 0.15 lasso 4 0.14 1.6e-07 6.3 5.7 9.3e-09 -0.08 0.96 0.00 FALSE
5 GTEx Artery Aorta RP11-958N24.1 0.09 0.00 enet 5 0.02 1.7e-02 1.8 5.7 1.1e-08 -0.14 0.09 0.04 FALSE
6 GTEx Artery Coronary NPIPA5 0.30 0.03 enet 13 0.07 3.1e-03 -6.6 6.8 1.2e-11 -0.02 0.02 0.79 FALSE
7 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 8.2 8.0 1.6e-15 -0.14 0.94 0.03 FALSE
8 GTEx Artery Tibial NPIPA1 0.15 0.05 lasso 3 0.04 2.0e-04 6.4 5.8 5.6e-09 -0.08 0.20 0.03 FALSE
9 GTEx Artery Tibial PKD1P6 0.11 0.05 lasso 5 0.03 2.4e-03 6.3 6.2 4.4e-10 -0.09 0.18 0.03 FALSE
10 GTEx Brain Caudate basal ganglia NPIPA2 0.23 0.08 lasso 7 0.13 1.3e-04 1.3 5.3 1.2e-07 -0.07 0.04 0.12 FALSE
11 GTEx Brain Hippocampus NPIPA3 0.26 0.00 lasso 12 0.01 1.5e-01 3.0 5.6 2.0e-08 0.12 0.04 0.06 FALSE
12 GTEx Breast Mammary Tissue RP11-958N24.1 0.08 0.04 enet 18 0.04 5.1e-03 6.4 5.9 3.2e-09 -0.08 0.04 0.11 FALSE
13 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 8.2 8.8 1.5e-18 -0.14 0.20 0.76 FALSE
14 GTEx Cells EBV-transformed lymphocytes PDXDC1 0.25 0.03 enet 20 0.05 1.1e-02 -8.5 5.9 3.5e-09 0.00 0.02 0.74 FALSE
15 GTEx Cells EBV-transformed lymphocytes NPIPA1 0.26 0.07 lasso 3 0.10 3.7e-04 6.2 6.8 8.1e-12 -0.10 0.06 0.16 FALSE
16 GTEx Cells EBV-transformed lymphocytes RP11-958N24.1 0.22 0.02 lasso 5 0.06 4.8e-03 -3.7 7.7 1.3e-14 -0.14 0.02 0.34 FALSE
17 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 8.2 8.3 9.9e-17 -0.15 0.72 0.28 FALSE
18 GTEx Colon Transverse RRN3 0.13 0.00 lasso 5 0.00 1.9e-01 8.0 -6.1 1.1e-09 0.11 0.02 0.32 FALSE
19 GTEx Esophagus Gastroesophageal Junction NPIPA1 0.19 0.15 lasso 2 0.10 1.4e-04 6.3 6.4 1.9e-10 -0.09 0.41 0.03 FALSE
20 GTEx Esophagus Mucosa RRN3 0.13 0.13 lasso 4 0.13 3.2e-09 8.0 7.3 2.6e-13 -0.14 0.92 0.08 FALSE
21 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 8.0 8.1 4.4e-16 -0.15 0.30 0.03 FALSE
22 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 8.0 8.0 1.3e-15 -0.14 0.04 0.46 FALSE
23 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 8.0 -7.7 1.4e-14 0.11 0.56 0.35 FALSE
24 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 8.2 8.5 2.3e-17 -0.14 0.02 0.71 FALSE
25 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 2.2 -6.8 1.5e-11 0.09 0.18 0.68 FALSE
26 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 8.0 7.0 2.4e-12 -0.13 0.96 0.03 FALSE
27 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 8.2 5.7 1.6e-08 -0.05 0.02 0.20 FALSE
28 GTEx Nerve Tibial RP11-958N24.1 0.11 0.06 lasso 1 0.04 7.6e-04 6.4 6.4 2.0e-10 -0.09 0.46 0.04 FALSE
29 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 8.2 8.2 1.8e-16 -0.14 0.93 0.06 FALSE
30 GTEx Skin Sun Exposed Lower leg PKD1P6 0.11 0.07 lasso 3 0.06 6.4e-06 6.4 6.7 2.8e-11 -0.09 0.75 0.01 FALSE
31 GTEx Small Intestine Terminal Ileum RP11-680G24.4 0.27 0.05 lasso 5 0.05 2.9e-02 -7.3 7.0 1.8e-12 -0.03 0.02 0.27 FALSE
32 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 8.2 8.2 1.8e-16 -0.14 0.11 0.14 FALSE
33 GTEx Testis RP11-958N24.1 0.09 0.10 lasso 2 0.07 6.1e-04 6.2 6.3 2.5e-10 -0.08 0.10 0.08 FALSE
34 GTEx Thyroid RP11-65J21.3 0.35 0.32 lasso 2 0.31 2.6e-24 -13.3 -13.3 1.6e-40 -0.54 1.00 0.00 TRUE
35 METSIM Adipose NOMO1 0.10 0.07 lasso 4 0.06 3.0e-09 6.4 6.4 1.8e-10 -0.09 1.00 0.00 FALSE
36 METSIM Adipose NTAN1 0.07 0.06 enet 12 0.06 1.7e-09 8.2 7.9 2.7e-15 -0.12 1.00 0.00 FALSE
37 METSIM Adipose PDXDC1 0.14 0.04 bslmm 148 0.06 3.0e-09 6.4 -5.5 3.0e-08 0.12 0.79 0.04 FALSE
38 METSIM Adipose RP11-1186N24.5 0.18 0.10 enet 24 0.13 4.6e-19 6.3 5.3 1.3e-07 -0.07 1.00 0.00 FALSE
39 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 8.2 8.2 2.5e-16 -0.09 0.02 0.03 FALSE
40 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -9.6 11.2 6.8e-29 -0.14 0.01 0.99 TRUE
41 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 8.0 8.8 2.0e-18 -0.14 1.00 0.00 FALSE
42 ROSMAP Brain Pre-frontal Cortex RP11-958N24.1 0.07 0.01 enet 7 0.02 1.9e-03 8.0 6.5 7.1e-11 -0.12 0.44 0.08 FALSE
43 ROSMAP Brain Pre-frontal Cortex NPIPP1 0.27 0.11 enet 15 0.14 2.2e-17 6.3 5.8 6.3e-09 -0.09 1.00 0.00 FALSE
44 ROSMAP Brain Pre-frontal Cortex PKD1P6 0.04 0.01 enet 10 0.01 4.3e-02 -4.5 -6.0 1.6e-09 0.07 0.03 0.10 FALSE
45 ROSMAP Brain Pre-frontal Cortex NPIPA2 0.48 0.26 bslmm 145 0.47 2.1e-68 6.4 -8.8 1.9e-18 0.06 1.00 0.00 FALSE
46 The Cancer Genome Atlas Bladder Urothelial Carcinoma RRN3 0.09 0.07 lasso 2 0.05 3.3e-05 6.4 7.3 2.4e-13 -0.12 0.80 0.03 FALSE
47 The Cancer Genome Atlas Colon Adenocarcinoma RRN3 0.07 0.00 blup 31 0.02 4.0e-02 6.4 5.2 1.6e-07 -0.13 0.01 0.04 FALSE
48 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RRN3 0.13 0.05 enet 17 0.10 3.5e-11 8.0 7.3 2.7e-13 -0.12 1.00 0.00 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma PDXDC1 0.03 0.00 enet 17 0.02 1.1e-03 -9.5 -5.2 1.7e-07 0.05 0.01 0.70 FALSE
50 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RRN3 0.17 0.07 lasso 2 0.07 4.9e-04 6.3 -5.8 5.2e-09 0.08 0.07 0.08 FALSE
51 The Cancer Genome Atlas Lung Adenocarcinoma RRN3 0.06 0.04 blup 31 0.05 3.1e-06 8.2 6.5 8.2e-11 -0.12 0.89 0.01 FALSE
52 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RRN3 0.03 0.00 blup 31 0.02 4.3e-03 6.4 7.5 7.3e-14 -0.13 0.04 0.11 FALSE
53 The Cancer Genome Atlas Prostate Adenocarcinoma ABCC6 0.16 0.04 enet 16 0.16 1.8e-16 3.0 5.4 7.1e-08 -0.07 0.02 0.09 TRUE
54 The Cancer Genome Atlas Thyroid Carcinoma ABCC1 0.07 0.07 lasso 5 0.06 1.5e-06 4.6 5.5 3.4e-08 -0.01 0.03 0.94 TRUE
55 The Cancer Genome Atlas Thyroid Carcinoma PDXDC1 0.25 0.12 enet 12 0.14 1.3e-13 -9.5 -6.1 9.3e-10 0.01 0.02 0.98 FALSE
56 The Cancer Genome Atlas Thyroid Carcinoma RRN3 0.09 0.06 lasso 2 0.07 1.6e-07 8.0 8.0 1.2e-15 -0.14 0.96 0.02 FALSE
57 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma ABCC1 0.32 -0.01 blup 228 0.01 1.4e-01 -1.2 6.2 7.2e-10 -0.06 0.02 0.09 TRUE