Best TWAS P=6.03e-08 · Best GWAS P=4.97e-08 conditioned to 0.361
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PSMF1 | 0.41 | 0.25 | lasso | 9 | 0.35 | 1.4e-29 | 5.1 | 5.4 | 6.4e-08 | 0.04 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | PSMF1 | 0.21 | 0.13 | lasso | 5 | 0.23 | 3.9e-12 | 5.1 | 5.3 | 1.3e-07 | 0.04 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | PSMF1 | 0.29 | 0.17 | lasso | 4 | 0.21 | 6.5e-07 | 5.1 | 5.4 | 7.8e-08 | 0.03 | 0.02 | 0.97 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | PSMF1 | 0.56 | 0.41 | lasso | 4 | 0.53 | 1.1e-46 | 5.1 | 5.3 | 1.0e-07 | 0.03 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Nerve Tibial | PSMF1 | 0.42 | 0.18 | lasso | 9 | 0.24 | 4.0e-17 | 5.1 | 5.3 | 1.3e-07 | 0.04 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Ovary | PSMF1 | 0.40 | 0.13 | lasso | 10 | 0.13 | 3.7e-04 | 5.1 | 5.4 | 6.0e-08 | 0.05 | 0.02 | 0.86 | TRUE |
| 7 | METSIM | Adipose | RBCK1 | 0.14 | 0.15 | lasso | 4 | 0.15 | 2.9e-21 | 5.5 | 5.3 | 1.1e-07 | 0.99 | 0.00 | 1.00 | FALSE |
| 8 | YFS | Blood | RBCK1 | 0.26 | 0.21 | bslmm | 485 | 0.23 | 6.6e-74 | 5.5 | 5.3 | 9.5e-08 | 0.90 | 0.00 | 1.00 | TRUE |