[Hub]/) : Traits : Height :

chr21:46,705,345-48,090,629

Best TWAS P=2.37e-13 · Best GWAS P=2.65e-30 conditioned to 2.83e-19

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex COL6A2 0.13 0.11 lasso 7 0.11 7.7e-14 7.2 6.4 1.3e-10 0.34 1.00 0.00 FALSE
2 GTEx Artery Coronary LSS 0.18 0.10 enet 9 0.07 1.9e-03 -2.9 -5.4 8.8e-08 -0.05 0.16 0.05 FALSE
3 GTEx Brain Frontal Cortex BA9 COL6A1 0.28 0.01 enet 43 0.01 1.9e-01 3.3 5.2 1.6e-07 0.09 0.09 0.05 TRUE
4 GTEx Esophagus Mucosa MCM3AP-AS1 0.18 0.07 enet 24 0.10 2.3e-07 2.2 6.0 2.3e-09 0.13 0.99 0.00 TRUE
5 GTEx Nerve Tibial MCM3AP 0.20 0.12 lasso 9 0.18 5.9e-13 -3.5 5.2 1.7e-07 0.07 1.00 0.00 FALSE
6 GTEx Pancreas DIP2A 0.13 0.12 enet 12 0.15 5.3e-07 -3.4 5.9 4.3e-09 0.11 0.62 0.02 FALSE
7 METSIM Adipose LSS 0.11 0.01 bslmm 485 0.06 6.4e-10 2.3 -6.1 1.1e-09 -0.11 0.98 0.00 TRUE
8 The Cancer Genome Atlas Lung Adenocarcinoma FTCD 0.04 0.03 blup 66 0.03 2.6e-04 -3.8 5.1 2.6e-07 0.16 0.16 0.03 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma COL6A2 0.05 0.00 blup 75 0.01 1.9e-02 8.7 7.3 2.4e-13 0.17 0.02 0.04 TRUE