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chr2:88,239,332-89,130,009

Best TWAS P=1.99e-68 · Best GWAS P=3.95e-69 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ANKRD36BP2	0.05	0.05	lasso	6	0.05	1.4e-06	-9.6	7.1	1.2e-12	0.45	0.95	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EIF2AK3	0.08	0.05	lasso	7	0.07	3.7e-09	15.1	12.9	6.4e-38	0.83	0.01	0.99	FALSE
3	GTEx	Artery Tibial	AC062029.1	0.14	0.10	enet	11	0.12	1.3e-09	16.5	17.5	2.0e-68	0.94	0.00	1.00	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	RPIA	0.27	0.01	enet	13	0.03	2.7e-02	-3.4	5.2	2.4e-07	0.08	0.16	0.04	TRUE
5	GTEx	Cells Transformed fibroblasts	RPIA	0.10	0.02	lasso	4	0.04	7.3e-04	-3.4	9.6	9.6e-22	0.51	0.12	0.57	FALSE
6	GTEx	Cells Transformed fibroblasts	AC062029.1	0.07	0.08	lasso	3	0.07	3.0e-06	17.6	17.2	2.5e-66	0.98	0.00	1.00	FALSE
7	GTEx	Esophagus Muscularis	EIF2AK3	0.08	0.02	lasso	3	0.03	5.9e-03	-4.6	5.8	7.3e-09	0.39	0.27	0.13	FALSE
8	GTEx	Lung	RPIA	0.16	0.00	enet	31	0.05	8.5e-05	-3.4	7.7	1.0e-14	0.37	0.09	0.06	TRUE
9	GTEx	Lung	AC062029.1	0.08	0.00	lasso	5	0.01	2.5e-02	-7.6	10.5	9.3e-26	0.57	0.06	0.22	FALSE
10	GTEx	Nerve Tibial	RPIA	0.10	0.03	lasso	10	0.04	1.3e-03	16.5	15.8	6.7e-56	0.80	0.06	0.33	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RPIA	0.09	0.03	enet	14	0.06	1.3e-05	-3.4	6.6	3.6e-11	0.16	0.31	0.03	TRUE
12	GTEx	Spleen	RPIA	0.36	0.03	enet	21	0.11	8.4e-04	-3.4	5.3	1.1e-07	0.25	0.15	0.10	FALSE
13	GTEx	Testis	RPIA	0.18	0.18	enet	9	0.18	2.0e-08	-6.2	6.4	1.6e-10	0.38	0.89	0.02	FALSE
14	GTEx	Thyroid	RPIA	0.07	0.00	lasso	6	0.02	1.8e-02	-3.4	6.8	1.2e-11	0.33	0.28	0.21	FALSE
15	NTR	Blood	RPIA	0.02	0.00	blup	197	0.01	4.1e-03	-8.7	-5.7	1.5e-08	-0.30	0.04	0.05	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	RPIA	0.05	0.05	blup	194	0.04	4.3e-06	15.1	12.3	5.0e-35	0.69	0.01	0.99	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	EIF2AK3	0.11	0.09	lasso	5	0.09	2.0e-11	17.6	16.7	1.4e-62	0.97	0.00	1.00	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	ANKRD36BP2	0.02	0.02	lasso	4	0.02	1.8e-03	-9.6	7.8	9.2e-15	0.47	0.17	0.05	FALSE
19	YFS	Blood	RPIA	0.05	0.04	lasso	12	0.05	1.1e-14	-9.1	-8.1	4.7e-16	-0.42	1.00	0.00	TRUE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPIA	0.05	0.02	lasso	3	0.02	2.6e-04	-6.2	10.9	1.4e-27	0.66	0.01	0.90	TRUE
21	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPIA	0.07	0.06	blup	34	0.06	7.3e-04	-3.2	6.4	1.4e-10	0.29	0.09	0.16	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPIA	0.05	0.02	blup	34	0.03	1.2e-04	-3.4	7.0	2.8e-12	0.33	0.45	0.10	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	EIF2AK3	0.13	0.01	enet	17	0.02	4.0e-03	17.6	9.8	1.6e-22	0.71	0.00	0.94	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPIA	0.07	0.00	blup	34	0.01	1.8e-02	15.1	10.4	2.1e-25	0.51	0.00	0.85	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPIA	0.05	0.01	blup	34	0.02	4.0e-03	15.1	10.6	5.0e-26	0.51	0.00	0.71	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	EIF2AK3	0.03	0.01	blup	54	0.02	1.1e-02	-7.6	9.3	8.8e-21	0.54	0.03	0.19	TRUE
27	The Cancer Genome Atlas	Thyroid Carcinoma	RPIA	0.20	0.03	enet	11	0.14	1.5e-13	-3.4	12.3	7.6e-35	0.64	0.02	0.98	TRUE