[Hub]/) : Traits : Height :

chr2:84,884,961-87,510,868

Best TWAS P=2.42e-20 · Best GWAS P=4.56e-24 conditioned to 1.86e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RNF181 0.07 0.02 bslmm 476 0.03 3.4e-04 9.1 8.0 1.2e-15 0.59 0.02 0.92 FALSE
2 GTEx Adipose Subcutaneous GGCX 0.16 0.09 lasso 5 0.08 3.1e-07 8.0 7.8 6.8e-15 0.71 0.99 0.00 FALSE
3 GTEx Adipose Visceral Omentum GGCX 0.13 0.03 lasso 7 0.03 1.1e-02 7.9 7.1 1.1e-12 0.68 0.32 0.27 FALSE
4 GTEx Artery Aorta GGCX 0.23 0.22 lasso 6 0.23 5.5e-13 7.9 8.8 1.8e-18 0.74 0.97 0.03 FALSE
5 GTEx Artery Tibial GGCX 0.29 0.22 enet 14 0.24 6.3e-19 7.8 8.3 8.8e-17 0.69 1.00 0.00 FALSE
6 GTEx Brain Cerebellar Hemisphere GGCX 0.46 0.41 enet 16 0.48 5.3e-14 6.3 8.1 4.6e-16 0.72 0.98 0.02 FALSE
7 GTEx Brain Cerebellum GGCX 0.54 0.30 lasso 10 0.34 6.0e-11 8.0 8.3 7.1e-17 0.75 0.96 0.04 FALSE
8 GTEx Brain Cortex GGCX 0.38 0.17 enet 30 0.02 1.1e-01 6.3 7.5 9.5e-14 0.60 0.48 0.18 FALSE
9 GTEx Brain Nucleus accumbens basal ganglia GGCX 0.28 0.09 enet 7 0.02 7.6e-02 6.3 7.9 3.0e-15 0.67 0.10 0.25 FALSE
10 GTEx Breast Mammary Tissue GGCX 0.14 0.01 lasso 3 0.01 1.0e-01 8.0 8.0 9.3e-16 0.69 0.13 0.11 FALSE
11 GTEx Breast Mammary Tissue (Male) GGCX 0.10 0.00 enet 4 0.00 3.3e-01 6.1 7.4 1.3e-13 0.69 0.06 0.09 FALSE
12 GTEx Cells EBV-transformed lymphocytes GGCX 0.36 0.31 enet 18 0.29 4.5e-10 6.2 7.8 4.2e-15 0.71 0.99 0.01 FALSE
13 GTEx Colon Transverse GGCX 0.26 0.28 lasso 3 0.28 1.4e-13 8.0 8.3 7.5e-17 0.73 0.98 0.02 FALSE
14 GTEx Esophagus Gastroesophageal Junction GGCX 0.24 0.16 lasso 6 0.12 4.3e-05 8.1 8.8 1.6e-18 0.74 0.38 0.38 FALSE
15 GTEx Esophagus Mucosa GGCX 0.29 0.21 enet 30 0.27 5.8e-18 7.8 7.6 2.8e-14 0.62 1.00 0.00 FALSE
16 GTEx Esophagus Mucosa VAMP8 0.41 0.31 lasso 6 0.36 6.6e-25 8.1 -6.9 3.9e-12 -0.66 1.00 0.00 FALSE
17 GTEx Esophagus Mucosa TMEM150A 0.10 0.05 enet 5 0.05 3.2e-04 8.0 -8.6 6.2e-18 -0.80 0.06 0.88 FALSE
18 GTEx Esophagus Muscularis GGCX 0.14 0.12 lasso 9 0.12 1.1e-07 7.9 8.2 3.6e-16 0.75 0.65 0.35 FALSE
19 GTEx Esophagus Muscularis AC015971.2 0.09 0.03 lasso 6 0.05 9.1e-04 -5.6 5.5 4.5e-08 0.02 0.04 0.86 TRUE
20 GTEx Lung GGCX 0.17 0.17 lasso 2 0.18 2.3e-13 8.1 8.1 6.9e-16 0.72 1.00 0.00 FALSE
21 GTEx Muscle Skeletal GGCX 0.10 0.04 enet 11 0.02 2.7e-03 7.9 9.2 2.4e-20 0.78 0.09 0.90 TRUE
22 GTEx Muscle Skeletal USP39 0.18 0.10 lasso 3 0.10 1.1e-09 7.6 -6.9 5.2e-12 -0.63 0.93 0.07 FALSE
23 GTEx Muscle Skeletal VAMP5 0.09 0.05 enet 23 0.05 5.7e-06 9.1 -6.7 1.7e-11 -0.66 0.05 0.95 FALSE
24 GTEx Nerve Tibial GGCX 0.38 0.30 lasso 7 0.33 6.5e-24 7.8 8.4 5.5e-17 0.72 1.00 0.00 FALSE
25 GTEx Pancreas VAMP5 0.29 0.09 enet 4 0.05 3.2e-03 6.5 -7.7 1.3e-14 -0.66 0.02 0.76 FALSE
26 GTEx Prostate GGCX 0.31 0.16 lasso 4 0.20 1.0e-05 6.3 5.7 9.3e-09 0.60 0.07 0.67 FALSE
27 GTEx Skin Not Sun Exposed Suprapubic GGCX 0.13 0.04 enet 11 0.06 3.9e-04 8.0 9.1 6.3e-20 0.64 0.34 0.15 FALSE
28 GTEx Skin Sun Exposed Lower leg GGCX 0.15 0.11 lasso 3 0.18 7.9e-15 8.0 8.4 4.1e-17 0.69 1.00 0.00 FALSE
29 GTEx Skin Sun Exposed Lower leg VAMP8 0.14 0.13 enet 19 0.13 5.4e-11 4.0 -5.7 1.1e-08 -0.49 1.00 0.00 FALSE
30 GTEx Testis GGCX 0.38 0.36 enet 25 0.40 8.6e-19 8.1 9.0 3.1e-19 0.72 0.83 0.17 FALSE
31 GTEx Thyroid ELMOD3 0.10 0.01 enet 10 0.02 7.7e-03 -4.7 6.2 7.5e-10 0.28 0.22 0.30 FALSE
32 GTEx Thyroid GGCX 0.30 0.17 enet 10 0.23 1.4e-17 8.0 8.9 6.9e-19 0.74 0.99 0.01 FALSE
33 GTEx Whole Blood CAPG 0.12 0.03 lasso 3 0.04 5.3e-05 4.8 -5.8 7.1e-09 -0.02 0.35 0.04 FALSE
34 GTEx Whole Blood GGCX 0.15 0.14 lasso 4 0.15 1.7e-13 8.0 8.4 3.5e-17 0.73 1.00 0.00 FALSE
35 METSIM Adipose GGCX 0.07 0.09 lasso 8 0.09 9.6e-14 6.1 7.2 5.7e-13 0.70 0.98 0.02 FALSE
36 METSIM Adipose VAMP5 0.05 0.03 lasso 8 0.01 2.9e-03 6.9 -7.8 5.7e-15 -0.71 0.29 0.70 FALSE
37 NTR Blood CAPG 0.11 0.05 bslmm 463 0.10 3.7e-29 -4.7 -5.5 2.9e-08 -0.14 1.00 0.00 FALSE
38 NTR Blood VAMP8 0.05 0.04 lasso 8 0.04 2.0e-12 7.4 -7.6 2.5e-14 -0.74 1.00 0.00 FALSE
39 ROSMAP Brain Pre-frontal Cortex GGCX 0.12 0.10 lasso 4 0.12 5.4e-15 6.8 6.3 3.5e-10 0.60 1.00 0.00 FALSE
40 ROSMAP Brain Pre-frontal Cortex USP39 0.34 0.31 enet 9 0.33 4.0e-43 6.7 -5.2 1.5e-07 -0.50 1.00 0.00 FALSE
41 ROSMAP Brain Pre-frontal Cortex VAMP5 0.09 0.01 enet 15 0.02 6.2e-04 1.3 -6.5 7.4e-11 -0.35 0.12 0.40 FALSE
42 YFS Blood CAPG 0.40 0.20 enet 65 0.37 1.2e-128 -4.7 -5.3 1.1e-07 -0.02 1.00 0.00 TRUE
43 YFS Blood VAMP8 0.15 0.15 enet 37 0.18 2.2e-55 7.8 -7.7 1.7e-14 -0.75 1.00 0.00 FALSE
44 The Cancer Genome Atlas Bladder Urothelial Carcinoma USP39 0.04 0.00 blup 68 0.01 1.8e-02 7.0 -8.0 8.8e-16 -0.78 0.01 0.78 FALSE
45 The Cancer Genome Atlas Breast Invasive Carcinoma SFTPB 0.03 0.02 blup 44 0.02 3.8e-05 7.6 -5.8 5.7e-09 -0.55 0.29 0.55 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma USP39 0.02 0.00 blup 67 0.01 1.7e-03 10.1 -8.1 7.4e-16 -0.78 0.01 0.92 FALSE
47 The Cancer Genome Atlas Colon Adenocarcinoma C2orf68 0.06 0.06 lasso 2 0.05 1.1e-03 9.1 -9.2 5.9e-20 -0.88 0.02 0.68 FALSE
48 The Cancer Genome Atlas Brain Lower Grade Glioma GGCX 0.05 0.05 lasso 1 0.04 1.2e-05 8.1 8.1 5.1e-16 0.72 0.77 0.06 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma USP39 0.07 0.05 lasso 5 0.05 5.2e-06 7.0 -5.3 1.3e-07 -0.51 0.90 0.04 FALSE
50 The Cancer Genome Atlas Brain Lower Grade Glioma VAMP5 0.06 0.04 lasso 2 0.04 3.2e-05 6.2 -5.8 6.2e-09 -0.63 0.15 0.71 FALSE
51 The Cancer Genome Atlas Brain Lower Grade Glioma VPS24 0.05 0.02 enet 12 0.03 2.9e-04 -5.5 5.4 7.9e-08 0.04 0.02 0.91 FALSE
52 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RNF103 0.06 0.02 blup 42 0.02 2.4e-02 4.9 -5.4 8.0e-08 -0.03 0.01 0.61 FALSE
53 The Cancer Genome Atlas Liver Hepatocellular Carcinoma USP39 0.10 0.07 blup 62 0.04 7.1e-03 6.9 -7.3 2.4e-13 -0.60 0.04 0.31 FALSE
54 The Cancer Genome Atlas Lung Adenocarcinoma RNF181 0.03 0.00 blup 39 0.01 1.5e-02 7.6 -6.7 2.8e-11 -0.67 0.01 0.52 FALSE
55 The Cancer Genome Atlas Lung Adenocarcinoma USP39 0.04 0.02 blup 67 0.03 2.0e-04 8.1 -8.4 6.1e-17 -0.76 0.07 0.83 FALSE
56 The Cancer Genome Atlas Lung Squamous Cell Carcinoma VAMP5 0.07 0.04 blup 44 0.05 2.1e-06 6.5 -5.9 3.1e-09 -0.49 0.33 0.40 FALSE
57 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RETSAT 0.12 0.01 blup 56 0.03 4.9e-03 -4.6 5.3 1.2e-07 0.05 0.01 0.25 FALSE
58 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma VAMP8 0.06 0.01 enet 15 0.02 2.1e-02 6.3 6.0 1.7e-09 0.45 0.05 0.09 FALSE
59 The Cancer Genome Atlas Prostate Adenocarcinoma GGCX 0.04 0.02 blup 44 0.02 2.7e-03 6.4 8.4 6.4e-17 0.72 0.18 0.53 FALSE
60 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM150A 0.06 0.05 lasso 3 0.04 3.9e-05 7.6 -7.6 2.6e-14 -0.70 0.47 0.35 FALSE
61 The Cancer Genome Atlas Prostate Adenocarcinoma USP39 0.09 0.12 lasso 2 0.11 1.5e-11 6.7 -6.7 2.5e-11 -0.64 1.00 0.00 FALSE
62 The Cancer Genome Atlas Soft Tissue Sarcoma GGCX 0.04 0.03 lasso 2 0.03 1.1e-02 7.8 7.8 6.9e-15 0.70 0.06 0.05 FALSE
63 The Cancer Genome Atlas Thyroid Carcinoma GGCX 0.03 0.03 enet 5 0.02 8.7e-03 7.2 7.9 3.9e-15 0.82 0.05 0.56 FALSE
64 The Cancer Genome Atlas Thyroid Carcinoma VAMP8 0.04 0.05 lasso 3 0.05 1.2e-05 7.8 -8.5 1.3e-17 -0.77 0.36 0.47 FALSE