Best TWAS P=1.72e-09 · Best GWAS P=5.05e-10 conditioned to 0.783
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | EPC2 | 0.18 | -0.01 | enet | 19 | 0.02 | 5.1e-02 | -4.7 | 6.0 | 1.7e-09 | 0.18 | 0.04 | 0.14 | TRUE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ORC4L | 0.07 | 0.04 | blup | 37 | 0.03 | 6.1e-04 | 6.1 | -5.4 | 8.1e-08 | -0.94 | 0.00 | 0.92 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ORC4L | 0.04 | 0.03 | enet | 7 | 0.03 | 5.4e-07 | -3.7 | -5.1 | 3.0e-07 | -0.59 | 0.29 | 0.62 | FALSE |