Best TWAS P=2.06e-10 · Best GWAS P=1.84e-15 conditioned to 2.63e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RPL15 | 0.04 | 0.02 | blup | 44 | 0.02 | 2.1e-04 | -5.2 | -5.4 | 5.6e-08 | 0.38 | 0.01 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | NR1D2 | 0.03 | 0.02 | enet | 4 | 0.04 | 5.5e-05 | -7.3 | -6.4 | 2.1e-10 | 0.49 | 0.05 | 0.66 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | NR1D2 | 0.08 | 0.01 | enet | 6 | 0.02 | 1.2e-02 | -6.1 | -5.7 | 1.2e-08 | 0.46 | 0.03 | 0.69 | FALSE |