Best TWAS P=7.22e-12 · Best GWAS P=1.75e-11 conditioned to 0.00549
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NEK10 | 0.04 | 0.03 | blup | 450 | 0.03 | 9.5e-05 | 4.6 | -6.8 | 7.2e-12 | -0.69 | 0.16 | 0.78 | TRUE |
| 2 | GTEx | Artery Aorta | SLC4A7 | 0.10 | 0.08 | enet | 15 | 0.08 | 5.4e-05 | -5.5 | -6.4 | 1.9e-10 | -0.48 | 0.30 | 0.45 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NEK10 | 0.02 | 0.02 | lasso | 4 | 0.02 | 1.3e-05 | -5.0 | 5.2 | 2.5e-07 | 0.41 | 0.74 | 0.20 | FALSE |