Best TWAS P=9.94e-15 · Best GWAS P=1.99e-25 conditioned to 1.48e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | SUCLG2 | 0.23 | 0.03 | enet | 47 | 0.08 | 9.9e-07 | -5.0 | 7.0 | 2.6e-12 | -0.46 | 0.02 | 0.97 | FALSE |
2 | GTEx | Artery Aorta | SUCLG2 | 0.23 | 0.02 | enet | 33 | 0.14 | 5.4e-08 | 1.9 | 5.3 | 9.3e-08 | -0.01 | 0.38 | 0.11 | FALSE |
3 | GTEx | Esophagus Mucosa | SUCLG2 | 0.29 | 0.14 | enet | 41 | 0.16 | 6.5e-11 | 3.8 | 5.2 | 1.9e-07 | -0.33 | 0.82 | 0.18 | FALSE |
4 | GTEx | Skin Not Sun Exposed Suprapubic | SUCLG2 | 0.28 | 0.15 | enet | 26 | 0.18 | 2.2e-10 | 3.8 | 6.7 | 2.8e-11 | -0.25 | 0.67 | 0.29 | TRUE |
5 | GTEx | Skin Sun Exposed Lower leg | SUCLG2 | 0.17 | 0.06 | enet | 13 | 0.13 | 4.2e-11 | 3.8 | 6.0 | 1.9e-09 | -0.27 | 0.65 | 0.35 | FALSE |
6 | GTEx | Spleen | SUCLG2 | 0.37 | -0.01 | enet | 35 | 0.01 | 1.8e-01 | 3.4 | 5.6 | 1.9e-08 | -0.17 | 0.06 | 0.14 | FALSE |
7 | ROSMAP | Brain Pre-frontal Cortex | SUCLG2 | 0.24 | 0.09 | enet | 37 | 0.19 | 2.4e-23 | 2.6 | 7.7 | 9.9e-15 | -0.47 | 0.15 | 0.85 | TRUE |
8 | The Cancer Genome Atlas | Thyroid Carcinoma | SUCLG2 | 0.15 | 0.00 | blup | 190 | 0.05 | 2.3e-05 | -3.4 | 6.2 | 6.2e-10 | -0.30 | 0.08 | 0.46 | FALSE |