Best TWAS P=5.7e-09 · Best GWAS P=1.71e-11 conditioned to 0.000312
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | PREPL | 0.18 | 0.08 | lasso | 7 | 0.06 | 1.0e-03 | -5.7 | 5.5 | 3.6e-08 | -0.90 | 0.11 | 0.75 | FALSE |
| 2 | GTEx | Pancreas | PREPL | 0.12 | 0.03 | lasso | 4 | 0.02 | 6.7e-02 | -5.7 | 5.5 | 3.9e-08 | -0.92 | 0.11 | 0.78 | FALSE |
| 3 | GTEx | Uterus | PREPL | 0.22 | 0.22 | lasso | 5 | 0.19 | 1.2e-04 | -6.1 | 5.8 | 5.7e-09 | -0.94 | 0.05 | 0.60 | TRUE |
| 4 | METSIM | Adipose | PREPL | 0.04 | 0.05 | lasso | 3 | 0.04 | 1.7e-06 | -5.8 | 5.5 | 3.6e-08 | -0.92 | 0.42 | 0.58 | FALSE |