Best TWAS P=1.13e-09 · Best GWAS P=2.9e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | STON1 | 0.40 | 0.23 | enet | 11 | 0.21 | 2.1e-06 | -5.3 | -5.4 | 5.2e-08 | 0.22 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | STON1 | 0.46 | 0.14 | lasso | 5 | 0.14 | 3.8e-04 | -5.6 | -5.5 | 3.7e-08 | 0.17 | 0.04 | 0.70 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | LHCGR | 0.06 | 0.04 | lasso | 4 | 0.02 | 4.3e-03 | -5.9 | -6.1 | 1.1e-09 | 0.97 | 0.00 | 0.98 | TRUE |