Best TWAS P=3.82e-09 · Best GWAS P=4.23e-10 conditioned to 0.0687
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | PRICKLE4 | 0.10 | 0.09 | lasso | 8 | 0.08 | 9.2e-07 | 4.4 | -5.8 | 8.8e-09 | 0.03 | 0.97 | 0.01 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PRICKLE4 | 0.04 | 0.05 | blup | 43 | 0.06 | 2.2e-07 | -4.4 | -5.1 | 2.7e-07 | 0.03 | 0.01 | 0.90 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FOXP4 | 0.04 | 0.02 | blup | 71 | 0.02 | 4.2e-03 | -6.2 | 5.9 | 3.8e-09 | -0.86 | 0.01 | 0.90 | TRUE |