Best TWAS P=6.06e-08 · Best GWAS P=5.36e-11 conditioned to 0.000102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | FIGNL1 | 0.30 | 0.07 | enet | 10 | 0.19 | 4.2e-07 | -3.9 | 5.1 | 3.0e-07 | 0.67 | 0.15 | 0.81 | FALSE |
| 2 | GTEx | Prostate | FIGNL1 | 0.52 | 0.29 | enet | 13 | 0.40 | 2.6e-11 | 5.4 | 5.4 | 6.1e-08 | 0.70 | 0.30 | 0.69 | TRUE |
| 3 | GTEx | Small Intestine Terminal Ileum | FIGNL1 | 0.21 | 0.23 | lasso | 4 | 0.22 | 1.3e-05 | 5.4 | 5.3 | 1.4e-07 | 0.61 | 0.17 | 0.39 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | DDC | 0.08 | 0.05 | blup | 137 | 0.03 | 4.5e-03 | -5.2 | -5.4 | 7.1e-08 | -0.57 | 0.12 | 0.13 | FALSE |