Best TWAS P=9.94e-08 · Best GWAS P=5.67e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | LIN52 | 0.08 | 0.07 | lasso | 4 | 0.07 | 4.6e-06 | 5.0 | 5.1 | 2.8e-07 | 0.97 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Liver | COQ6 | 0.26 | -0.01 | enet | 14 | 0.02 | 7.5e-02 | 4.9 | 5.2 | 2.3e-07 | 0.81 | 0.03 | 0.82 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | LIN52 | 0.23 | 0.20 | enet | 10 | 0.20 | 9.4e-10 | 5.0 | 5.3 | 1.2e-07 | 0.89 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | LIN52 | 0.06 | 0.05 | lasso | 4 | 0.04 | 5.7e-04 | 5.0 | 5.3 | 9.9e-08 | 0.96 | 0.02 | 0.94 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LIN52 | 0.10 | 0.08 | lasso | 2 | 0.10 | 1.7e-07 | 5.0 | 5.3 | 1.3e-07 | 0.96 | 0.01 | 0.98 | FALSE |