Best TWAS P=3.65e-15 · Best GWAS P=2.83e-15 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | RP11-849F2.8 | 0.22 | 0.09 | enet | 30 | 0.13 | 3.3e-09 | -2.0 | 5.4 | 5.4e-08 | 0.32 | 0.85 | 0.13 | FALSE |
| 2 | YFS | Blood | TMEM107 | 0.17 | 0.17 | lasso | 5 | 0.19 | 2.0e-61 | 7.9 | 7.9 | 3.6e-15 | 0.97 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C17orf68 | 0.05 | 0.00 | blup | 59 | 0.03 | 3.3e-04 | 7.7 | 5.5 | 3.5e-08 | 0.81 | 0.00 | 0.96 | FALSE |