Best TWAS P=1.47e-07 · Best GWAS P=2.12e-07 conditioned to 0.411
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | CTD-2619J13.17 | 0.13 | 0.11 | enet | 10 | 0.08 | 8.8e-05 | 5.2 | 5.1 | 2.8e-07 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Lung | CTD-2619J13.17 | 0.09 | 0.13 | lasso | 2 | 0.12 | 1.5e-09 | -5.2 | 5.2 | 2.0e-07 | -1.00 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Nerve Tibial | CTD-2619J13.17 | 0.07 | 0.03 | lasso | 5 | 0.05 | 2.1e-04 | 5.2 | 5.1 | 2.9e-07 | -0.98 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZNF584 | 0.03 | 0.02 | enet | 5 | 0.03 | 1.5e-03 | -5.0 | 5.3 | 1.5e-07 | -0.93 | 0.01 | 0.89 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF132 | 0.03 | 0.01 | lasso | 1 | 0.00 | 1.9e-01 | 5.2 | 5.2 | 2.1e-07 | -0.98 | 0.01 | 0.76 | FALSE |
| 6 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ZNF132 | 0.07 | 0.07 | blup | 54 | 0.06 | 6.3e-04 | -5.2 | 5.1 | 2.8e-07 | -0.92 | 0.02 | 0.94 | FALSE |