Best TWAS P=5.77e-16 · Best GWAS P=1.25e-16 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ADSL | 0.04 | 0.03 | enet | 6 | 0.03 | 0.00016 | -3.9 | -5.2 | 2.5e-07 | -0.69 | 0.04 | 0.44 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ADSL | 0.08 | 0.02 | enet | 5 | 0.02 | 0.00232 | -5.9 | -5.3 | 1.2e-07 | -0.65 | 0.05 | 0.33 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SGSM3 | 0.06 | 0.01 | lasso | 4 | 0.01 | 0.07420 | 8.3 | -8.1 | 5.8e-16 | -0.95 | 0.00 | 0.94 | TRUE |