[Hub]/) : Traits : Chronotype (morning person) :

chr22:41,498,627-43,226,599

Best TWAS P=1.01e-08 · Best GWAS P=1.04e-09 conditioned to 2.25e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CYP2D6 0.26 0.10 enet 34 0.20 1.2e-16 -4.5 -5.3 1.3e-07 -0.10 0.74 0.26 FALSE
2 GTEx Adrenal Gland CYP2D6 0.37 0.14 lasso 12 0.16 2.3e-06 -4.6 -5.3 1.4e-07 -0.07 0.55 0.43 FALSE
3 GTEx Artery Coronary CYP2D6 0.24 0.18 lasso 7 0.17 1.8e-06 -5.0 -5.2 1.6e-07 -0.10 0.67 0.27 FALSE
4 GTEx Brain Cerebellum SLC25A5P1 0.24 0.11 enet 16 0.14 7.3e-05 -5.0 5.7 1.0e-08 0.18 0.32 0.12 TRUE
5 GTEx Breast Mammary Tissue CYP2D6 0.14 0.00 enet 28 0.02 3.4e-02 -4.6 -5.2 1.6e-07 -0.35 0.09 0.32 FALSE
6 GTEx Muscle Skeletal CYP2D6 0.10 0.06 enet 17 0.08 3.4e-08 -4.5 -5.5 3.6e-08 -0.15 0.87 0.13 FALSE
7 GTEx Spleen CCDC134 0.23 0.00 enet 14 0.09 2.7e-03 -3.9 5.1 2.7e-07 0.12 0.06 0.14 FALSE