[Hub]/) : Traits : Neuroticism : ← →

chr5:86,867,897-88,677,293

Best TWAS P=2.92e-12 · Best GWAS P=9.1e-11 conditioned to 0.734

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC645323	0.05	0.01	blup	72	0.01	2.8e-02	-4.5	7.0	2.9e-12	0.47	0.02	0.17	TRUE
3	ROSMAP	Brain Pre-frontal Cortex	LINC00461	0.10	0.07	lasso	2	0.05	4.5e-07	6.1	6.1	1.3e-09	0.89	0.01	0.98	TRUE
6	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM161B	0.03	0.01	blup	48	0.01	4.6e-02	4.3	5.8	6.6e-09	0.18	0.00	0.12	TRUE
4	ROSMAP	Brain Pre-frontal Cortex	TMEM161B-AS1	0.05	0.02	lasso	6	0.04	2.1e-05	3.8	5.5	5.0e-08	0.24	0.89	0.03	FALSE
2	GTEx	Brain Hippocampus	TMEM161B-AS1	0.17	0.10	enet	13	0.08	5.4e-03	5.1	5.4	5.7e-08	0.21	0.12	0.07	FALSE
1	GTEx	Brain Cortex	TMEM161B-AS1	0.35	0.15	lasso	15	0.30	6.5e-09	4.2	5.4	7.9e-08	0.30	0.77	0.04	FALSE