Best TWAS P=5.57e-11 · Best GWAS P=3.07e-10 conditioned to 0.15
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ASXL3 | 0.04 | 0.01 | blup | 83 | 0.02 | 0.0076 | -5.1 | -5.4 | 5.8e-08 | -0.64 | 0.04 | 0.69 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ASXL3 | 0.12 | 0.04 | lasso | 3 | 0.02 | 0.0384 | -6.1 | -6.6 | 5.6e-11 | -0.84 | 0.02 | 0.93 | TRUE |